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| 1 | Gastric cancer in Alaska Native people: A cancer health disparity显示文摘AIM To evaluate recent trends in gastric cancer incidence, response to treatment, and overall survival among Alaska Native(AN) people. METHODS A retrospective analysis of the Alaska Native Medical Center patient database was performed. Patient history, clinical, pathological, response to treatment and patient outcomes were collected from one-hundred and thirty-two AN gastric cancer patients. The Surveillance, Epidemiology and End Result database 18 was used to collect comparison United States non-Hispanic White(NHW) and AN gastric cancer patient data between 2006-2014.RESULTS AN gastric cancer patients have a higher incidence rate, a poorer overall survival, and are diagnosed at a significantly younger age compared to NHW patients. AN patients differ from NHW patients in greater prevalence of non-cardia, diffuse subtype, and signet ring cell carcinomas. AN females were more likely to be diagnosed with later stage cancer, stage IV, compared to AN males. Diminished overall survival was observed among AN patients with increasing stage, O+ blood type, < 15 lymph nodes examined at resection, and no treatment. This study is the first report detailing the clinicopathologic features of gastric cancer in AN people with outcome data.CONCLUSION Our findings confirm the importance of early detection, treatment, and surgical resection for optimizing AN patient outcomes. Further research on early detection markers are warranted. | Holly A Martinson Nancy J Shelby Steven R Alberts Matthew J Olnes | 2018 | World Journal of Gastroenterology2018，24，25： | 6 |
| 2 | A comparison of the relative efficiency of ICSI and extended culture with epididymal sperm versus testicular sperm in patients with obstructive azoospermia显示文摘This is a retrospective cohort study comparing blastocyst transfer outcomes following intracytoplasmic sperm injection utilizing epididymal versus testicular sperm for men with obstructive azoospermia.All cases at a single center between 2012 and 2016 were included.Operative approach was selected at the surgeon’s discretion and included microepididymal sperm aspiration or testicular sperm extraction.Blastocyst culture was exclusively utilized prior to transfer.The primary outcome was live birth rate.Secondary outcomes included fertilization rate,blastulation rate,euploidy rate,and implantation rate.A mixed effects model was performed.Seventy-six microepididymal sperm aspiration cases and 93 testicular sperm extraction cases were analyzed.The live birth rate was equivalent(48.6%vs 50.5%,P=0.77).However,on mixed effects model,epididymal sperm resulted in a greater likelihood of fertilization(adjusted OR:1.37,95%CI:1.05–1.81,P=0.02)and produced a higher blastulation rate(adjusted OR:1.41,95%CI:1.1–1.85,P=0.01).As a result,the epididymal sperm group had more supernumerary blastocysts available(4.3 vs 3,P<0.05).The euploidy rate was no different.Pregnancy rates were no different through the first transfer cycle.However,intracytoplasmic sperm injection following microepididymal sperm aspiration resulted in a greater number of usable blastocysts per patient.Thus,the true benefit of epididymal sperm may only be demonstrated via a comparison of cumulative pregnancy rates after multiple transfers from one cohort. | Scott J Morin Brent M Hanson Caroline R Juneau Shelby A Neal Jessica N Landis Richard T Scott Jr James M Hotaling | 2020 | Asian Journal of Andrology2020，22，2： | 2 |
| 3 | Experimental verification of a negative index of refraction显示文摘 | Shelby R A Smith D R Schuha S | 2001 | Science2001，292，： | 1 |
| 4 | Experimental Verification of a Negative Index of Refraction显示文摘 | SHELBY R A SMITH D R SCHULTZ S | 2001 | Science2001，292，： | 1 |
| 5 | Experimental Verification of a Negative Index of Refraction显示文摘 | SHELBY R A SMITH D R SCHULTZ S | 2001 | Science2001，292，5514： | 1 |
| 6 | Experimental verification of a negative index of refraction显示文摘 | SHELBY R A SMITH D R SCHULTZ S | 2001 | Science2001，292，10： | 1 |
| 7 | Experimental verification of a negative index of refraction显示文摘 | SHELBY R A SMITH D R SCHULTZ S | 2001 | Science2001，292，4： | 1 |
| 8 | Bacillomycin D:an iturin with antifungal activity against Aspergillus flavus显示文摘 | Moyne A L Shelby R Cleveland T E | 2001 | J Appl Microbiol2001，90，： | 1 |
| 9 | Experimental verification of a negative index of refraction显示文摘 | SHELBY R A SMITH D R SCHUTZ S | 2001 | Science2001，292，5514： | 1 |
| 10 | Experimental verification of a negative index of refraction显示文摘 | Smith D R Schultz S | 2001 | Science2001，292，： | 1 |
| 11 | Experimental verification of a negative index of refraction显示文摘 | Shelby R A Smith D R Sebahz S | 2001 | Science2001，292，6： | 1 |
| 12 | Experimental verification of a negative refractive index of refraction 显示文摘 | SHELBY R A SMITH D R SCHULTZ S | 2001 | Science2001，292，6： | 1 |
| 13 | Ergot alkaloids: sources,structures and analytical methods显示文摘 | FLIEGER M WURST M SHELBY R | 1997 | Folia Microbiol1997，42，1： | 1 |
| 14 | Experimental verification of a negative index of refraction显示文摘 | R Shelby D R Smith and S Schultz | 2001 | Science2001，292，： | 1 |
| 15 | Bacillomycin D:an iturin with antifungal activity against Aspergillus flavus显示文摘 | Moyne AL Shelby R Cleveland TE | 2001 | J Appl Microbiol2001，90，4： | 1 |
| 16 | Experimental verification of a negative index of refraction显示文摘 | SHELBY R A SMITH D R SCHULTZ S | 2001 | Science2001，292，6： | 1 |
| 17 | Bacillomycin D:aniturin with antifungal activity against Aspergillus flavus显示文摘 | MOYNE A L SHELBY R CLEVELAND T E | 2001 | Journal of Ap-plied Microbiology2001，90，： | 1 |
| 18 | Microwave transmission through a two-dimensional, isotropic, left-handed metamaterial 显示文摘 | Shelby R A Smith D R Nemat-Nasser S C | 2001 | Appl Phys Lett2001，78，： | 1 |
| 19 | Experimental verification of a negative index of refraction显示文摘 | Shelby R A Smith D R Schultz S | | 0，，5514： | 1 |
| 20 | Experimental verification of a negative index of refraction显示文摘 | SHELBY R A SMITH D R SCHULTZ S | 2001 | Science2001，292，： | 1 |
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