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| 1 | Retrograde-viewing device improves adenoma detection rate in colonoscopies for surveillance and diagnostic workup显示文摘AIM:To determine which patients might benefit most from retrograde viewing during colonoscopy through subset analysis of randomized,controlled trial data.METHODS:The Third Eye Retroscope Randomized Clinical Evaluation(TERRACE) was a randomized,controlled,multicenter trial designed to evaluate the efficacy of a retrograde-viewing auxiliary imaging device that is used during colonoscopy to provide a second video image which allows viewing of areas on the proximal aspect of haustral folds and flexures that are difficult to see with the colonoscope's forward view.We performed a post-hoc analysis of the TERRACE data to determine whether certain subsets of the patient population would gain more benefit than others from use of the device.Subjects were patients scheduled for colonoscopy for screening,surveillance or diagnostic workup,and each underwent same-day tandem examinations with standard colonoscopy(SC) and Third Eye colonoscopy(TEC),randomized to SC followed by TEC or vice versa.RESULTS:Indication for colonoscopy was screening in 176/345 subjects(51.0%),surveillance after previous polypectomy in 87(25.2%) and diagnostic workup in 82(23.8%).In 4 subjects no indication was specified.Previously reported overall results had shown a net additional adenoma detection rate(ADR) with TEC of 23.2% compared to SC.Relative risk(RR) of missing adenomas with SC vs TEC as the initial procedure was 1.92(P = 0.029).Post-hoc subset analysis shows additional ADRs for TEC compared to SC were 4.4% for screening,35.7% for surveillance,55.4% for diagnostic and 40.7% for surveillance and diagnostic combined.The RR of missing adenomas with SC vs TEC was 1.11(P = 0.815) for screening,3.15(P = 0.014) for surveillance,8.64(P = 0.039) for diagnostic and 3.34(P = 0.003) for surveillance and diagnostic combined.Although a multivariate Poisson regression suggested gender as a possibly significant factor,subset analysis showed that the difference between genders was not statistically significant.Age,bowel prep quality and withdrawal time did not significantly affect the RR of missing adenomas with SC vs TEC.Mean sizes of adenomas detected with TEC and SC were similar at 0.59 cm and 0.56 cm,respectively(P = NS).CONCLUSION:TEC allows detection of significantly more adenomas compared to SC in patients undergoing surveillance or diagnostic workup,but not in screening patients(ClinicalTrials.gov Identifier:NCT01044732). | Peter D Siersema Amit Rastogi Anke M Leufkens Paul A Akerman Kassem Azzouzi Richard I Rothstein Frank P Vleggaar Alessandro Repici Giacomo Rando Patrick I Okolo Olivier Dewit Ana Ignjatovic Elizabeth Odstrcil James East Pierre H Deprez Brian P Saunders Anthony N Kalloo Bradley Creel Vikas Singh Anne Marie Lennon Daniel C DeMarco | 2012 | World Journal of Gastroenterology2012，18，26： | 6 |
| 2 | Preoperative chemotherapy : updates of National Surgical Adjuvant Breast and Bowel Project Protocols B 18 and B 27 显示文摘 | Rastogi P Anderson SJ Bear HD | 2008 | JClin Oncol2008，26，77： | 1 |
| 3 | Somaclonal variation: a new dimension for sugarcane improvement显示文摘 | Rastogi J Siddhant P B Sharma B L | 2015 | GERF Bulletin of B ioscienees2015，6，1： | 1 |
| 4 | Fringe analysis: premise and per- spectives 显示文摘 | Rajshekhar G Rastogi P | 2012 | Optics & Laers in Engineering2012，50，8： | 1 |
| 5 | Evaluation of lapatinib as a component of neoadjuvant therapy for HER -2+ operable breast cancer: nsabp protocol B-41 显示文摘 | Robidoux A Tang G Rastogi P | 2012 | J Clin Oncol302012，30，18： | 1 |
| 6 | Preoperative chemotherapy:updates of National Surgical Adjuvant Breast and Bowel Project Protocols B-18 and B-27显示文摘 | Rastogi P Anderson S Bear HD | 2008 | J Clin Oncol2008，26，5： | 1 |
| 7 | Preoperative chemotherapv:updates of National Surgical Adjuvant Breast and Bowel Project Pro-tocols B-18 and B-27显示文摘 | Rastogi P Anderson SJ Bear HD | | 0，，05： | 1 |
| 8 | Ultra-weak photon emission as a non-invasive tool for the measurement of oxidative stress induced by UVA radiation in Arabidopsis thaliana显示文摘 | RASTOGI A POSPISIL P | 2013 | Journal of Photochemistry and Photobiology B:Biology2013，123，1： | 1 |
| 9 | Pressure dependence of catalysed and inhibited burning rate of composite solid propellants显示文摘 | Rastogi R P Syal V | 1989 | Indian Journal of Chemistry1989，28，： | 1 |
| 10 | Prohibitin inducesthe transcriptional activity of p53 and is exported from thenucleus upon apoptotic signaling 显示文摘 | Fusaro G Dasgupta P Rastogi S | 2003 | J Biol Chem2003，278，47： | 1 |
| 11 | Estimating net aquifer recharge and zonal hydraulic conductivity values for Mahi Right Bank Canal project area, India by genetic algorithm显示文摘 | Lakshmi P K Rastogi A K | 2001 | Journal of Hydrology2001，243，3： | 1 |
| 12 | Efficacy and safety of rapid escalation of cabergoline in comparison to conventional regimen for macroprolactinoma:a prospective randomized trial显示文摘 | Rastogi A Walia R Dutta P | | 0，，2： | 1 |
| 13 | Nicotine induces cell proliferation, invasion and epithelial-mesenchymal transition in a variety of human cancer cell lines 显示文摘 | Dasgupta P Rizwani W Pillai S Kinkade R Kovacs M Rastogi S | 2009 | lnt J Cancer2009，124，1： | 1 |
| 14 | Bevacizumab added to neo- adjuvant chemotherapy for breast cancer 显示文摘 | Bear HD Tang G Rastogi P | 2012 | N Engl J Med2012，366，4： | 1 |
| 15 | Relative humidity sensor with optical Bragg gratings 显示文摘 | KRONENBERG P RASTOGI P K GIACCARI P M | 2002 | Optical Letters2002，127，16： | 1 |
| 16 | Preoperative chemotherapy: updates of national surgical adjuvant breast and bowel project protocols B-18 and B-27 显示文摘 | RASTOGI P ANDERSON S J BEAR H D | 2008 | J Clin On- col2008，26，5： | 1 |
| 17 | Preoperative chemotherapy:updates of National Surgical Adjuvant Breast and Bowel Project Pro-tocols B-18 and B-27显示文摘 | Rastogi P Anderson SJ Bear HD | 2008 | J Clin 0ncol2008，26，5： | 1 |
| 18 | Detection ofaflatoxin M1 contamination in milk and infant milk products from Indian markets by ELISA显示文摘 | Rastogi S Dwivedi P D Khanna S K | 2004 | Food Control2004，15，4： | 1 |
| 19 | Fringe projection techniques: whither we are? 显示文摘 | GORTHI S S RASTOGI P | 2010 | Optics and Lasers in Engineering2010，48，2： | 1 |
| 20 | The architecture of the Dali main-memory storage rnanager显示文摘 | Bohannon P Lieuwen D Rastogi R | 1997 | Journal of Multi-media Tools and Applications1997，4，2： | 1 |
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