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| 1 | 青少年特发性脊柱侧凸患者治疗前后的椎旁表面肌电活动的研究显示文摘目的探讨青少年特发性脊柱侧凸的患者在包括手法在内的综合治疗前后的脊柱旁肌电活动特点。方法选择9例确诊的特发性脊柱侧凸的患者,在乳突下、C1、T1、T3、T6、T9、T12、L3、L5位置记录为期24周的综合治疗前后的椎旁的肌电活动。结果在综合治疗前:7例上位凸起的对侧枕下肌电活动过高;6例下位凸起侧的L5/S1段肌电活动过高;6例从C5到L3单侧肌电活动过高。所有患者过高肌电活动发生在两弯曲中的一个的凹侧。综合治疗后:左右枕下SEMG值对称。上位或下位弯曲的SEMG值要么对称,要么在凸侧肌电活动过高。同侧L5/S1的SEMG值与下位弯曲凸侧一样。对治疗前后的SEMG值进行配对T检验,P<0.001。在前两周,患者过高肌电活动抑制很明显。经过7周的治疗,从凹侧至凸侧的过高肌电活动的交换在所有患者都明显并保持到治疗结束。结论综合治疗可以使凹侧的肌电活动过高转变为双侧平衡或凸侧肌电活动过高时,弯曲发展可以被阻止。一旦平衡建立,弯曲的阻止和活动的交换就会贯穿整个治疗过程。 | Raymond Wiegand D .C . | 2005 | 颈腰痛杂志2005，26，3： | 4 |
| 2 | Efficacy of boceprevir, an NS3 protease inhibitor, in combination with peginterferon alfa-2b and ribavirin in treatment-naive patients with genotype 1 hepatitis C infection (SPRINT-1): an open-label, randomised, multicentre phase 2 trial显示文摘 | Paul Y Kwo Eric J Lawitz Jonathan McCone Eugene R Schiff John M Vierling David Pound Mitchell N Davis Joseph S Galati Stuart C Gordon Natarajan Ravendhran Lorenzo Rossaro Frank H Anderson Ira M Jacobson Raymond Rubin Kenneth Koury Lisa D Pedicone Clifford | 2010 | The Lancet2010，，9742： | 3 |
| 3 | Consortium for the Human Information and Neurocognitive Endophenotype (CHINE) in China's Mainland: An example from neurological soft signs for neuropsychiatric disorders显示文摘Increasing efforts to identify alternate expressions of neuropsychiatric disorders that are broader than the DSM or ICD diagnostic criteria needed to diagnose them reflects a growing consensus that multidimensional expressions of neuropsychiatric disorders may advance the search for underlying etiological or modulatory factors. Endophenotypic research can be considered to be one of the most promising strategies to bridge the gap between genomic complexity and the phenotypic heterogeneity observed in neuropsychiatric disorders. However, the majority of endophenotype studies were limited to our western counterparts, very little has been done and initiated by scholars in China's Mainland. In this paper, we urge the need to establish a potential central consortium for endophenotypes to study neuropsychiatric disorders in China's Mainland. In particular, we illustrate a potential example of neurological soft signs in following the steps for building the consortium. | CHAN Raymond C K | 2011 | Chinese Science Bulletin2011，56，32： | 3 |
| 4 | Hepatocellular carcinoma in Lebanon: Etiology and prognostic factors associated with short-term survival显示文摘瞄准:在黎巴嫩和早死亡预兆的预示的因素学习 HCC 的传染病学。方法:在一个五年的时期上诊断的 HCC 盒子的观察后续队研究被执行。Multivariate 分析被进行与肝意大利的程序(片断) 分数的癌症相比识别预示的因素。包括内在的肝疾病,病人的人口统计的特征,和孩子呸评估的肝疾病的严厉的病原学的多重变量得分被学习。肿瘤参数包括了小瘤,门静脉血栓的存在,和治疗形式的 HCC, alpha-fetoprotein 水平,数字和尺寸的诊断的时间。后续的死亡或损失被看作一个端点事件。结果:92 个病人(平均数 60.5 +/- 22.3 年) 被包括。内在的疾病的病原学分别地是在 67% , 20% ,和 23.5% 的肝炎 B, C,和酒精。在诊断的孩子呸班分别地是在 34.8% , 39.3% 和 25.8% 的 A, B,和 C。全面幸存分别地在 1, 2 和 3 年是 44.8% , 32.8% 和 17.6%( 吝啬的 F/U 40.2 +/- 23.5 瞬间) 。Multivariate 分析识别了早死亡的三个预言者(<
6 瞬间) :胆红素 >
3.2 mg/dL (P <
0.01 ) , HCC 作为肝疾病的第一个演讲(P = 0.035 ) ,并且肌酸酐 >
1 mg/dL (P = 0.017 ) 。一个分数由考克斯基于这些变量超过了片断分数比例的危险。巨鸟曲线显示了两个模型相等、中等精确。结论:HBV 是在黎巴嫩的 HCC 的领先的原因。早死亡的独立预言者是象疾病的第一表明的提高的胆红素,肌酸酐和 HCC。一个分数的未来的确认基于在预言短期的幸存的这些临床的参数被需要。 | César Yaghi Ala I Sharara Paul Rassam Rami Moucari Khalil Honein Joseph BouJaoude Rita Slim Roger Noun Heitham Abdul-Baki Mohamad Khalifeh Sami Ramia Raymond Sayegh | 2006 | World Journal of Gastroenterology2006，12，22： | 3 |
| 5 | A family study of endophenotypes for psychosis within an early intervention programme in Hong Kong: Rationale and preliminary findings显示文摘The study of endophenotypes may be a viable strategy to tackle the genetic complexity and phenotypic heterogeneity of psychosis, but this research direction is relatively under-developed in China as compared to Western countries. We have recently initiated one of the first family studies of endophenotypes for psychosis in China. Patients entering an established early psychosis intervention service are recruited into this research project for phenotyping, endophenotyping and genotyping. At the endophenotypic level, four domains (neurological soft signs, neurocognition of prospective memory, social cognition of facial emotion recognition, and affective cognition of anticipatory and consummatory pleasure) are studied in the sample of patients with psychosis and their unaffected siblings. This article illustrates the benefit of a research-oriented clinical programme and its findings based on the data collected as of early 2011. | LUI Simon S Y SHAM Pak CHAN Raymond C K CHEUNG Eric F C | 2011 | Chinese Science Bulletin2011，56，32： | 2 |
| 6 | Antitumor activity of oxaliplatin in combination with 5-fluorouracil and thymidylate synthase inhibifor AG337 in human colon,breast and ovarian 显示文摘 | Raymond E Buquet-Fagot C Djellul | 1997 | Anticancer drugs1997，8，： | 2 |
| 7 | 斑皮桉生长性状及木材材性遗传参数估算显示文摘分别以位于澳大利亚新南威尔士州北部沿海地区Urunga、Coffs Harbour、Grafton和Casino的4个斑皮桉无性系试验作为研究对象,测定其林木生长性状和木材材性并进行遗传参数估算。研究表明,林木生长性状和木材材性均受到较高的遗传控制,胸径和树高的广义遗传力(H2)在0.46~0.71之间,Pilodyn值的广义遗传力在0.52~0.77之间,FAKOPP值的广义遗传力在0.64~0.85之间;Pilodyn值与FAKOPP值呈显著的正相关关系,但二者与胸径均无显著相关性;环境因子对生长性状和木材材性的影响显著;遗传与环境交互作用对木材材性影响不显著,但对生长性状如胸径有一定影响。 | 兰俊 吴永富 罗建中 吴兵 Raymond C A | 2011 | 桉树科技2011，28，2： | 2 |
| 8 | Is there an anatomical endophenotype for neurodevelopmental disorders? A review of dual disorder anatomical likelihood estimation (ALE) meta-analyses of grey matter volumes显示文摘The term 'neurodevelopmental disorder' broadly encompasses conditions thought to arise early in development and includes schizophrenia, bipolar disorder and autism among others. These conditions share a number of genetic and environmental risk factors postulated to lead to common difficulties in socio-emotional processing, communication and cognitive function. The alternative position is that, while the same traits are affected across these conditions, the nature or direction in which they are modified may be distinct. MRI studies provide a rapidly expanding and rich database which we propose can be used to contribute to this debate. Anatomical likelihood estimation (ALE) is a method of meta-analysis applied to voxel-based MRI studies. We have adapted this method to explore the extent to which schizophrenia and bipolar disorder and schizophrenia and autism share a common brain structural phenotype. We will review this work here and discuss whether there is sufficient other evidence to justify a common framework for further research into the inter-relatedness of such conditions. | MCALONAN Grainne M YU Kevin K CHAN Raymond C K CHUA Siew E CHEUNG Charlton | 2011 | Chinese Science Bulletin2011，56，32： | 2 |
| 9 | Predicting extractives, lignin, and cellulose contents using near infrared spectroscopy on solid wood in Eucalyptus globulus显示文摘 | POKE F S RAYMOND C A J | 2006 | Wood Chem Technol2006，26，2： | 1 |
| 10 | Phase Ⅰ and pharmacokinetic study of etaracizumab (Abegrin) , a humanized monoclonal antibody against alphavbeta3 integrin receptor, in patients with advanced solid tumors显示文摘 | Delbaldo C Raymond E Vera K | 2008 | Invest New Drugs2008，26，1： | 1 |
| 11 | Pharmacotherapeutic options for the treatment of depression in patients with chronic kidney disease显示文摘 | RAYMOND C B WAZNY L D HONCHARIK P L | 2008 | Nephrol Nurs J2008，35，26： | 1 |
| 12 | Time-scale for adjustment of glaciers to change in mass balance显示文摘 | Johannesson T Raymond C Waddington E | 1989 | Journal of Glaciology1989，35，121： | 1 |
| 13 | Temporal carbon dynamics of forests in Washington, US : Implications for ecological theory and carbon management显示文摘 | Raymond C L McKenzie D | 2013 | Forest Ecology and Management2013，310，： | 1 |
| 14 | Effects of thinning in progeny tests on estimates of genetic parameters in Pinus radiata显示文摘 | Matheson A C Raymond C A | 1984 | Silvae Genetica1984，33，： | 1 |
| 15 | Rickettsia-like organism infecting juvenile sea-bass Dicentrarchus labrax 显示文摘 | Raymond J C Plassiart G N | 1996 | Bull Eur Assoc Fish Pathol1996，16，： | 1 |
| 16 | Causes of failure in network organizations 显示文摘 | Raymond E Miles Charles C Snow | 1992 | California Management Review1992，34，4： | 1 |
| 17 | Phosphorylation of amino acid neurotransmitter receptors in synaptic plasticity显示文摘 | RAYMOND L A BLACKSTONE C D HUGANIR R L | 1993 | Trends Neurosci1993，16，： | 1 |
| 18 | Impact of precommercial thinning in balsam fir stands on soil N dynamics, microbial biomass, decomposition, and foliar nutrition 显示文摘 | THIBODEAU L RAYMOND P CAMIRE C | 2000 | Canadian Journal of Forest Research2000，30，： | 1 |
| 19 | Importance of Molar Ratios in Selenium-dependent Protection against Methylmercury Toxicity 显示文摘 | Ralston N C V Blackwell llI J L Raymond L J | 2007 | Biological Trace Element Research2007，119，3： | 1 |
| 20 | Selection of probiotic bacteria for the fermentation of a soy beverage in combination with Streptococcus thermophilus显示文摘 | CHAMPAGNE C P GREEN-JOHNSON J RAYMOND Y | 2009 | Food Res Int2009，42，： | 1 |
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