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| 1 | Relationship between Th17 immune response and cancer显示文摘Cancer is the second leading cause of death worldwide and epidemiological projections predict growing cancer mortality rates in the next decades.Cancer has a close relationship with the immune system and,although Th17 cells are known to play roles in the immune response against microorganisms and in autoimmunity,studies have emphasized their roles in cancer pathogenesis.The Th17 immune response profile is involved in several types of cancer including urogenital,respiratory,gastrointestinal,and skin cancers.This type of immune response exerts pro and antitumor functions through several mechanisms,depending on the context of each tumor,including the protumor angiogenesis and exhaustion of T cells and the antitumor recruitment of T cells and neutrophils to the tumor microenvironment.Among other factors,the paradoxical behavior of Th17 cells in this setting has been attributed to its plasticity potential,which makes possible their conversion into other types of T cells such as Th17/Treg and Th17/Th1 cells.Interleukin(IL)-17 stands out among Th17-related cytokines since it modulates pathways and interacts with other cell profiles in the tumor microenvironment,which allow Th17 cells to prevail in tumors.Moreover,the IL-17 is able to mediate pro and antitumor processes that influence the development and progression of various cancers,being associated with variable clinical outcomes.The understanding of the relationship between the Th17 immune response and cancer as well as the singularities of carcinogenic processes in each type of tumor is crucial for the identification of new therapeutic targets. | Hanna Santos Marques Breno Bittencourt de Brito Filipe Antônio França da Silva Maria Luísa Cordeiro Santos Júlio César Braga de Souza Thiago Macêdo Lopes Correia Luana Weber Lopes Nayara Silva de Macêdo Neres Rafael Santos Dantas Miranda Dórea Anna Carolina Saúde Dantas Lorena Lôbo Brito Morbeck Iasmin Souza Lima Amanda Alves de Almeida Maiara Raulina de Jesus Dias Fabrício Freire de Melo | 2021 | World Journal of Clinical Oncology2021，12，10： | 5 |
| 2 | Late Cenozoic eolian deposition in the North Pacific: Asian drying, Tibetan uplift, and cooling of the northern hemisphere显示文摘 | Rea D K Snoeckx H Joseph L H | 1998 | Paleoceanography1998，3，： | 3 |
| 3 | Late Cenozoic eolian deposition in the North Pacific: Asian drying, Tibetan uplift and cooling of the Northern Hemisphere 显示文摘 | Rea D K Snoeckx H Joseph L H | 1998 | Paleoceanography1998，13，： | 1 |
| 4 | Late Cenozoic eolian deposition in the North Pacific: Asian drying, Tibetan uplift, and cooling of the northern hemisphere 显示文摘 | Rea D K Snoeckx H Joseph L H | 1998 | Paleoceanography1998，13，3： | 1 |
| 5 | Late Cenozoic eolian deposition in the North Pacific: Asia drying, Tibetan uplift and cooling of the Northern Hemisphere显示文摘 | Rea D K Snoeckx H Joseph L H | 1998 | Paleoceanography1998，13，： | 1 |
| 6 | Timing and sequence of the onset of overweight, dieting, and binge eating in overweight patients with binge eating disorder 显示文摘 | REAS D L GRILO C M | 2007 | Int J Eat Disord2007，40，2： | 1 |
| 7 | Late Cenozoic Eolian Deposition in the North Pacific:Asian Drying,Tibetan Uplift,and Cooling of the Northern Hemisphere显示文摘 | Snoeckx H Joseph L P | 1998 | Paleocepnography1998，15，3： | 1 |
| 8 | Late Cenozoic eolian deposition in the North Pacific:Asian drying,Tibetan uplift,and cooling of the northern hemisphere显示文摘 | Rea D K Snoeckx H Joseph L H 1998 | 1998 | Paleoceanography1998，13，3： | 1 |
| 9 | Late Cenozoic eolian deposition in the North Pacific: Asian drying, Tibetan uplift, and cooling of the northern hemisphere显示文摘 | Rea D K Snoeckx H and Joseph l H | 1998 | Paleoceanography1998，13，： | 1 |
| 10 | Late Cenozoic eolian deposition in the North Pacific: Asian drying, Tibetan uplift,and cooling of the Northern Hemisphere 显示文摘 | Rea D K Snoeckx H Joseph L P | 1998 | Paleocepnography1998，15，3： | 1 |
| 11 | Late Cenozoic Eolian Deposition in the North Pacific:Asian Drying, Tibetan Uplift, and Cooling of the Northern Hemisphere显示文摘 | Rea D K Snoeckx H Joseph L H | 1998 | Paleoceanography1998，13，3： | 1 |
| 12 | Late Cenozoic eolian deposition in the North Pacific:Asian drying,Tibetan uplift & cooling of the Northern Hemisphere显示文摘 | REA D K SNOECKX H JOSEPH L H | 1998 | Paleoceanography1998，13，： | 1 |
| 13 | Late Cenozoic eolian deposition in the northern Pacific:Asian drying,Tibet uplift,and cooling of the northern hemisphere显示文摘 | Rea D K Snoeckx H Joseph L H | 1998 | Palaeoceanography1998，13，： | 1 |
| 14 | Factors impeding dispatcher-assisted telephone cardiopulmonary resuscita- tion显示文摘 | Hauff S R Rea T D Culley L L | 2003 | Ann Emerg Meal2003，42，6： | 1 |
| 15 | Protein-modified porous silicon nanostructures 显示文摘 | STEFANO L D REA I GIARDINA P | 2008 | Adv Mater2008，20，8： | 1 |
| 16 | Late Ceonozoic eolian deposition in the North Pacific: Asia drying, Tibetan uplift and cooling of the Northem Hemisphere 显示文摘 | Rea D K Snoeckx H Joseph L H | 1998 | Paleoceanography1998，13，： | 1 |
| 17 | Late Cenozoic eolian deposition in the North Pacific: Asian drying, Tibetan uplift, and cooling of the northern hemisphere显示文摘 | Rea D K Snoeckx H Joseph L H | 1998 | Paleoceanography1998，13，： | 1 |
| 18 | Late Cenozoic eolian deposition in the North Pacific:Asian drying,Tibetan uplift,and cooling of the Northern Hemisphere显示文摘 | Rea D K Snoeckx H joseph L H | 1998 | Paleoceanography1998，13，： | 1 |
| 19 | Late Cenozoic eolian deposition in the north Pacific:Asian drying, Tibetan uplift, and cooling of the Northern Hemisphere显示文摘 | Rea D K Snoeckx H Joseph L P | 1998 | Paleocepnography1998，15，3： | 1 |
| 20 | Composition and mass flux of sediment en- tering the world*s subduction zones : Implications for global sed- iment budgets, great earthquakes,and volcanism显示文摘 | Rea D K Ruff L J | 1996 | Earth and Planetary Science Letters1996，140，14： | 1 |
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