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| 1 | Hepatitis B virus mutations potentially conferring adefovir/ tenofovir resistance in treatment-naive patients显示文摘Anti-hepatitis B virus(HBV)therapy leads to the emer- gence of mutant viral strains during the treatment of chronic hepatitis B with nucleos(t)ides analogues. The existence of HBV variants with primary antiviral resistance may be important for treatment choice. We studied two patients with chronic HBV infection by sequencing the HBV polymerase gene.They had adefovir-and tenofovir-related mutations in the viral polymerase,although they had never been treated. These mutations were rtV214A/rtN238T in one patient and rtA194T in the other.Thus,mutations in untreated patients deserve cautious surveillance.These data indicate that mutations that can theoretically confer adefovir or tenofovir resistance may emerge in treatmentnaive patients. | Rebecca Pastor Franois Habersetzer Samira Fafi-Kremer Michel Doffoёl Thomas F Baumert Jean-Pierre Gut Franoise Stoll-Keller Evelyne Schvoerer | 2009 | World Journal of Gastroenterology2009，15，6： | 6 |
| 2 | Dev Cell:科学家阐明人类胚胎原生殖细胞发育的分子机制显示文摘近日,刊登于国际杂志Developmental Cell上的一项研究报道中,来自巴布拉汉研究所(Babraham Insdtute)的研究人员通过研究调查了原生殖细胞发育的早期阶段,同时他们在实验室开发了一种产生类似细胞的策略,这种酷似人类原始生殖细胞的产生对于未来生殖领域的研究,以及分析人类潜在的继代基因调控的遗传机制非常重要。 | Ferdinand von Meyenn Rebecca V. Berrens Simon Andrews Fátima Santos Amanda J. Collier Felix Krueger Rodrigo Osorno Wendy Dean Peter J. Rugg-Gunn Wolf Reik | 2016 | 现代生物医学进展2016，16，35： | 2 |
| 3 | LIGHT, a New Member of the TNF Superfamily, and Lymphotoxin α Are Ligands for Herpesvirus Entry Mediator显示文摘 | Davide N Mauri Reinhard Ebner Rebecca I Montgomery Kristine D Kochel Timothy C Cheung Guo-Liang Yu Steve Ruben Marianne Murphy Roselyn J Eisenberg Gary H Cohen Patricia G Spear Carl F Ware | 1998 | Immunity1998，，： | 1 |
| 4 | Epidemiological and molecular trends of norwalk - like viruses associated with outbreaks of gastroenteritis in the United States 显示文摘 | REBECCA L F STEPHAN S M JACQUELINE S N | 2002 | J Infec Dis2002，186，： | 1 |
| 5 | Breast cancer metastasis suppressor 1 (BRMS1) inhibits osteopontin transcription by abrogating NF-kB activation显示文摘 | RAJEEV S S DAVID W C REBECCA A F | 2007 | Molecular Cancer2007，6，： | 1 |
| 6 | Apoptosis and Bcl-2 expression in normal human endometrlum, endometrlosis and adenomyosis显示文摘 | REBECCA K JONES ROGER F | 1998 | Human Reproduction1998，13，12： | 1 |
| 7 | An Evaluation of Web-based Information显示文摘 | Susie F Peter W | 2004 | Int J Disord2004，35，： | 1 |
| 8 | Xenorhabdus bovienii T228 phase variation and virulence are independent of RecA function显示文摘 | HEW F THOMAR J | 2000 | Microbiology2000，146，： | 1 |
| 9 | Influence of ionic strength, pH, and cation valence on aggregation kinetics of titanium dioxide nanoparticles 显示文摘 | Rebecca A F Astrid R J Bojeong K | 2009 | Environment Science Technology2009，43，： | 1 |
| 10 | P2X receptor antagonists for pain management:examination of binding and physicochenaical properties显示文摘 | Rebecca J Gum Brain Wakefield Michael F Jarvis | 2012 | Purinergic Signal2012，8，1： | 1 |
| 11 | The BBZDR/Wor ratmodel for investigating the complications of type 2 diabetesmellitus显示文摘 | Rebecca S Tirabassi R Joan F | 2004 | ILAR Journa2004，45，3： | 1 |
| 12 | Flipping the classroom to improve student performance and satisfaction显示文摘 | Kathy M Rebecca F Lynn S | 2013 | J Nurs Educ2013，52，10： | 1 |
| 13 | Screening for simian Type-D retrovirus infection in Macaques,using nested polymerase chain reaction 显示文摘 | Nicholas W Rebecca F Mona D | 1997 | Laboratory Animal Science1997，47，3： | 1 |
| 14 | Microfluidic systems with on -line UV detection fabricated in photodefinable epoxy显示文摘 | Rebecca J J Tamara M F Reza G | 2001 | J Micromech Microeng2001，11，： | 1 |
| 15 | Programming infant gut microbiota: influence of dietary and environmental factors显示文摘 | Tatiana Milena Marques Rebecca Wall R Paul Ross Gerald F Fitzgerald C Anthony Ryan Catherine Stanton | 2010 | Current Opinion in Biotechnology2010，，2： | 1 |
| 16 | Comparison of an espB gene fecal polymerase chain reaction assay with bacteriologic isolation for detection of Citrobacter rodentium infection in mice显示文摘 | Rebecca M Nicholas D Patricia L F | 2002 | Comparative Medicine2002，52，5： | 1 |
| 17 | Prevalence of and Risk Factors for Hepatic Steatosis and Nonalcoholic Fatty Liver Disease in People With Type 2 Diabetes: the Edinburgh Type 2 Diabetes Study显示文摘 | Williamson Rachel M Price Jackie F Glancy Stephen Perry Elisa Nee Lisa D Hayes Peter C Frier Brian M Van Look Liesbeth A F Johnston Geoffrey I Reynolds Rebecca M Strachan Mark W J | 2011 | Diabetes Care2011，，5： | 1 |
| 18 | Interaction of flavonoids with bovine serum albumin: A fluorescence quenching study显示文摘 | ATHINA P REBECCA J RICHARD A F | 2005 | J Agric Food Chem2005，53，1： | 1 |
| 19 | Dielectric properties of lignin and glucomannan as determined by spectroscopic ellipsometry and Lifshitz estimates of non-retarded Hamaker constants显示文摘 | Rebecca H Hans A Bertrand F | 2013 | Cellulose2013，，20： | 1 |
| 20 | Chitosan supports the initial attachment and spreading of osteoblasts preferentially over fibroblasts显示文摘 | Ali F Galen BS Rebecca Z | 2004 | Biomaterials2004，25，： | 1 |
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