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| 1 | Low-grade gliomas:do changes in rCBV measurements at longitudinal perfusion-weighted MR imaging predict malignant transformation?显示文摘Radiology. 2008 Apr;247(1):170-8.PURPOSE: To prospectively perform longitudinal magnetic resonance (MR) perfusion imaging of conservatively treated low-gradegliomas to determine whether relative cerebral blood volume (rCBV) changes precede malignant transformation as defined | Danchaivijitr N Waldman AD Tozer DJ Benton CE Brasil Caseiras G Tofts PS Rees JH J?ger HR | 2008 | 中国神经肿瘤杂志2008，6，2： | 7 |
| 2 | Refining pathological evaluation of neoadjuvant therapy for adenocarcinoma of the esophagus显示文摘AIM:To assess tumour regression grade(TRG)and lymph node downstaging to help define patients who benefit from neoadjuvant chemotherapy.METHODS:Two hundred and eighteen consecutive patients with adenocarcinoma of the esophagus or gastro-esophageal junction treated with surgery alone or neoadjuvant chemotherapy and surgery between 2005and 2011 at a single institution were reviewed.Triplet neoadjuvant chemotherapy consisting of platinum,fluoropyrimidine and anthracycline was considered for operable patients(World Health Organization performance status≤2)with clinical stage T2-4 N0-1.Response to neoadjuvant chemotherapy(NAC)was assessed using TRG,as described by Mandard et al.In addition lymph node downstaging was also assessed.Lymph node downstaging was defined by cN1 at diagnosis:assessed radiologically(computed tomography,positron emission tomography,endoscopic ultrasonography),then pathologically recorded as N0 after surgery;ypN0 if NAC given prior to surgery,or pN0if surgery alone.Patients were followed up for 5 years post surgery.Recurrence was defined radiologically,with or without pathological confirmation.An association was examined between t TRG and lymph node downstaging with disease free survival(DFS)and a comprehensive range of clinicopathological characteristics.RESULTS:Two hundred and eighteen patients underwent esophageal resection during the study interval with a mean follow up of 3 years(median follow up:2.552,95%CI:2.022-3.081).There was a 1.8%(n=4)inpatient mortality rate.One hundred and thirty-six(62.4%)patients received NAC,with 74.3%(n=101)of patients demonstrating some signs of pathological tumour regression(TRG 1-4)and 5.9%(n=8)having a complete pathological response.Forty four point one percent(n=60)had downstaging of their nodal disease(cN1 to ypN0),compared to only 15.9%(n=13)that underwent surgery alone(pre-operatively overstaged:cN1 to pN0),(P<0.0001).Response to NAC was associated with significantly increased DFS(mean DFS;TRG 1-2:5.1years,95%CI:4.6-5.6 vs TRG 3-5:2.8 years,95%CI:2.2-3.3,P<0.0001).Nodal down-staging conferred a significant DFS advantage for those patients with a poor primary tumour response to NAC(median DFS;TRG 3-5 and nodal down-staging:5.533 years,95%CI:3.558-7.531 vs TRG 3-5 and no nodal down-staging:1.114 years,95%CI:0.961-1.267,P<0.0001).CONCLUSION:Response to NAC in the primary tumour and in the lymph nodes are both independently associated with improved DFS. | Fergus Noble Luke Nolan Adrian C Bateman James P Byrne Jamie J Kelly Ian S Bailey Donna M Sharland Charlotte N Rees Timothy J Iveson Tim J Underwood Andrew R Bateman | 2013 | World Journal of Gastroenterology2013，19，48： | 4 |
| 3 | Analysis and design for a class of complex control systems, Part Ⅱ: fuzzy controller design显示文摘 | CAO S G REES N W FENG G | 1997 | Automatica1997，33，： | 1 |
| 4 | Development of gfp yectors for expression in Listeria monocytogenes and other low G + C gram positive bacteria 显示文摘 | QAXI S N A REES C E D MELLITS K H | 2001 | Microbiology Ecology2001，41，4： | 1 |
| 5 | Further results about quadratic stability of continuous-time fuzzy control systems显示文摘 | Cao S G Rees N W Feng G | 1997 | System Science1997，28，4： | 1 |
| 6 | Temporal variability of denitrification in estuarine sediments显示文摘 | LAW C S REES A P OWENS N J P | 1991 | Estuarine Coastal and Shelf Science1991，33，1： | 1 |
| 7 | Nonlinear gas turbine modeling using NARMAX Structures显示文摘 | N Chiras C Evans D Rees | 2001 | IEEE Transactions On Instrumentation And Measurement2001，，： | 1 |
| 8 | Nitrous oxide: Estuarine sources and atmospheric flux 显示文摘 | LAW C S REES A P OWENS N J P | 1992 | Estuarine Coastal and Shelf Science1992，35，3： | 1 |
| 9 | A survey of standing column well installations in North America 显示文摘 | ORIO C D JOHNSON C N REES S J | 2005 | ASHRAE Transactions2005，111，2： | 1 |
| 10 | Management of tendinopathy显示文摘 | Rees JD Maffulli N Cook J | 2009 | Am J Sports Med2009，37，9： | 1 |
| 11 | Acupuncture of chronic headache disorders in primary care: randomised controlled trial and economic analysis 显示文摘 | Vickers A J Rees RW Zollman CE McCarney R Smith CM Ellis N | 2004 | Health Technol Assess2004，8，48： | 1 |
| 12 | Analysis and design for a complex control system, part I: fuzzy modeling and identification显示文摘 | Cao S G Rees N W Feng G | 1997 | Automatica1997，6，： | 1 |
| 13 | Electrochemical CO2 se- questration in ionic liquids: a perspective 显示文摘 | REES N V COMPTON R G | 2011 | Energy Environmental Science2011，4，2： | 1 |
| 14 | Scheduling control of a deaerator ptant显示文摘 | Lu C X Bell R D Rees N W | 1998 | Control Engineering Practice1998，6，12： | 1 |
| 15 | Analysis and design for a class of complex control systems显示文摘 | CAO G S REES N W FENG G | 1997 | Automatica1997，33，6： | 1 |
| 16 | Analysis and Design for a Class of Complex Control Systems ,Part I: Fuzzy Modeling and Identification显示文摘 | CAO S G REES N W FENG G | 1997 | Automatica1997，33，6： | 1 |
| 17 | Formation of native prions from minimal components in vitro 显示文摘 | Deleault N R Harris B T Rees J R | 2007 | Proc Natl Acad Sci USA2007，104，： | 1 |
| 18 | New threshold and confidence estimates for terminal restriction fragment length polymorphism analysis of complex bacterial communities 显示文摘 | OSBRONE C A REES G N JANSSEN P H | 2006 | Applied and Environmental Microbiology2006，72，2： | 1 |
| 19 | p57kip2 immunohistochemical staining of gestational trophoblastic tumours does not identify the type of the causative pregnancy显示文摘 | Sebire N J Rees H C Peston D | 2004 | Histopathology2004，45，2： | 1 |
| 20 | Resolution of inverse agonist-induced up-regulation from constitutive activity of mutants of the α1B-adrenoceptor显示文摘 | Stevens PA Bevan N Rees S etal | 2000 | MolPharmacol2000，58，2： | 1 |
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