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218篇 您的检索式：作者名="REGIS J"

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	题名	作者	年代	出处	被引量
1	Notch signaling controls chondrocyte hypertrophy via indirect regulation of Sox9显示文摘RBPjk-dependent Notch signaling regulates both the onset of chondrocyte hypertrophy and the progression to terminal chondrocyte maturation during endochondral ossification. It has been suggested that Notch signaling can regulate Sox9 transcription, although how this occurs at the molecular level in chondrocytes and whether this transcriptional regulation mediates Notch control of chondrocyte hypertrophy and cartilage development is unknown or controversial. Here we have provided conclusive genetic evidence linking RBPjk-dependent Notch signaling to the regulation of Sox9 expression and chondrocyte hypertrophy by examining tissuespecific Rbpjk mutant(Prx1Cre;Rbpjkf/f), Rbpjk mutant/Sox9 haploinsufficient(Prx1Cre;Rbpjkf/f;Sox9f/1),and control embryos for alterations in SOX9 expression and chondrocyte hypertrophy during cartilage development. These studies demonstrate that Notch signaling regulates the onset of chondrocyte maturation in a SOX9-dependent manner, while Notch-mediated regulation of terminal chondrocyte maturation likely functions independently of SOX9. Furthermore, our in vitro molecular analyses of the Sox9 promoter and Notch-mediated regulation of Sox9 gene expression in chondrogenic cells identified the ability of Notch to induce Sox9 expression directly in the acute setting, but suppresses Sox9 transcription with prolonged Notch signaling that requires protein synthesis of secondary effectors.	Anat Kohn Timothy P Rutkowski Zhaoyang Liu Anthony J Mirando Michael J Zuscik Regis J O'Keefe Matthew J Hilton	2015	Bone Research2015，3，3：	8
2	Gamma knife surgery for mesial temporal lobe epilepsy显示文摘	Bartolomei F Rey M	1999	Epilepsia1999，40，11：	1
3	Radiosurgery for drug-resistant epilepsies: state of the art, results and perspectives显示文摘	Regis J Arkha Y Yomo S	2008	Neurochirurgie2008，54，3：	1
4	Pineal region tumors: the role of stereotactic radissurgery显示文摘	MABNERA L REGIS J CHINOTO	1996	Stereotact Funct Neurosurg1996，66，1：	1
5	Periprosthetic osteolysis: an immunologist?s update显示文摘	R John Looney Edward M Schwarz Allen Boyd Regis J O?Keefe	2006	Current Opinion in Rheumatology2006，，1：	1
6	Mood disorder as a manifestation of primary hy- poparathyroidism:A case report显示文摘	Regis G Rosa Alcina J S Barros Antonio RB de Lima	2014	Journal of Medical Case Reports2014，8，4：	1
7	valuation of fractionated radiotherapy and gamma knife radiosurgery in cavernous sinus meningiomas: treatment strategy显示文摘	Metellus P Regis J Muraceiole X	2005	Neurosurgery2005，57，5：	1
8	Gamma knife radiosurgery for brainstem arteriovenous malformations显示文摘	Regis J Kondziolka D	2000	J Neurosurg2000，93，1：	1
9	Gamma knife surgery for mesial temporal lobe epilepsy 显示文摘	Regis J Bartolomei F Rey M	2000	J Neurosurg2000，93，3：	1
10	Gamma knife radiosurgery in the management of cavernous sinus meningiomas显示文摘	Roche P H Regis J Dufour H	2000	J Neurosurg2000，93，3：	1
11	Silicon incorporation in hydroxyapatite obtained by controlled crystallization显示文摘	Arcos D Rodriguez Carvajal J Vallet Regi M	2004	Chem Mater2004，16，6：	1
12	In vitro bioactivity of glass and glass-ceramics of the 3CaO·P2O5-CaO·SiO2-CaO·MgO·2SiOm2 system显示文摘	Salinasa AJ Romana J Valet-regia Regi Ma	2000	Biomaterials2000，21，：	1
13	Role of stereotactic radiosurgery in the management of pituitary adenomas 显示文摘	CASTINET'FI F REGIS J DUFOUR H	2010	Nat Rev Endocrinol2010，6，4：	1
14	Pineal region tumors and the role of stereotactic biopsy:review of the mortality,morbidity and diagnostic rates in 370 cases显示文摘	Regis J Bouillot P Rouby-Volot F	1996	Neurosurgery1996，39，：	1
15	Radiosurgery for t rigeminal neuralgia and epilepsy显示文摘	REGIS J BARTOLOMEI F METELLUS P	1999	Neurosurg Clin Nor Am1999，10，2：	1
16	Gamma knife surgery in mesial temporal lobe epilepsy: a prospective multicenter study 显示文摘	Regis J Rey M Bartolomei F	2004	Epilepsia2004，45，5：	1
17	Gamma knife surgery for epilepsy related to hypothalamie hamartoma 显示文摘	Regis J Scavarda D Tamura M	2007	Semin Pediatr Neurol2007，14，2：	1
18	Epilepsy related to hypothalamic hamartomas:surgical mauagement with special reference to gamma knife surgery显示文摘	Regis J Scavarda D Tamura M		0，，：	1
19	Testing for PPP in australia : Evidence from unit root tests against nonlinear trend stationarity alematives 显示文摘	Cuestas J C Regis P J	2008	Economics Bulletin2008，，3：	1
20	Effect of the gamma knife on trigeminal neuralgia 显示文摘	Regis J	1995	Stereotact Furtct Neurosurg1995，64，：	1

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