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| 1 | Disagreement between symptom-reflux association analysis parameters in pediatric gastroesophageal reflux disease investigation显示文摘AIM: To assess the agreement within 3 commonly used symptom-reflux association analysis (SAA) parameters investigating gastroesophageal reflux disease (GERD) in infants. METHODS: Twenty three infants with suspected GERD were included in this study. Symptom index (SI), Symptom sensitivity index (SSI) and symptom association probability (SAP) related to cough and irritability were calculated after 24 h combined pH/multiple intraluminal impedance (MII) monitoring. Through defined cutoff values, SI, SSI and SAP values are differentiated in normal and abnormal, whereas abnormal values point towards gastroesophageal reflux (GER) as the origin of symptoms. We analyzed the correlation and the concordance of the diagnostic classification of these 3 SAA parameters.RESULTS: Evaluating the GER-irritability association, SI, SSI and SAP showed non-identical classification of normal and abnormal cases in 39.2% of the infants. When irritability was taken as a symptom, there was only a poor inter-parameter association between SI and SSI, and between SI and SAP (Kendall’s tau b = 0.37, P < 0.05; Kendall’s tau b = 0.36, P < 0.05, respectively). Evaluating the GER-cough association, SI, SSI and SAP showed non-identical classification of normal and abnormal cases in 52.2% of the patients. When cough was taken as a symptom, only SI and SSI showed a poor inter-parameter association (Kendall’s tau b = 0.33, P < 0.05). CONCLUSION: In infants investigated for suspected GERD with pH/MII-monitoring, SI, SSI and SAP showed a poor inter-parameter association and important dis-agreements in diagnostic classification. These limitations must be taken into consideration when interpreting the results of SAA in infants. | Samuel C Lüthold Mascha K Rochat Peter Bhler | 2010 | World Journal of Gastroenterology2010，16，19： | 3 |
| 2 | Sequentially evolved bilateral epidural haematomas显示文摘 | Rochat P Johannesen HH Poulsgrd L | 2002 | Clin Neurol Neurosurg2002，105，1： | 1 |
| 3 | Immune modulation of blood leukocytes in humans by lactic acid bacteria:criteria for strain selection显示文摘 | Schiffrin E J Brassart D Servin A L Rochat F Donnet Hughes A | | 0，，： | 1 |
| 4 | Storage reserve accumulation in Arabidop- sis 显示文摘 | Baud S Dubreucq B Miquel M Rochat C Lepi- niec L | 2008 | Plant Cell2008，34，5： | 1 |
| 5 | The role of impulsivity in actual and problematic me of the mobile phone显示文摘 | Billieux J Martial V D L Rochat L | 2008 | Applied Cognitive Psychology2008，，9： | 1 |
| 6 | The role of impulsivity in actual and problematic use of the mobile phone显示文摘 | Billieux J van Der Linden M Rochat L | 2008 | Appl Cognit Psychol2008，22，9： | 1 |
| 7 | Maternal mortality in the United States: report from the maternal mortality collaborative显示文摘 | Rochat R W Koonin L M Atrash H K | 1988 | Obstet Gynecol1988，72，1： | 1 |
| 8 | Rational choice under unequal constrains: The example of Belgin higher education显示文摘 | Rochat D Demeulemeester J L | 2001 | Economics of Education Review2001，20，1： | 1 |
| 9 | Low-threshold terahertz quantum-cascade lasers显示文摘 | ROCHAT M AJIU L WILLENBERG H | 2002 | Appl Phys Lett2002，81，8： | 1 |
| 10 | Quantitative performance of a quadrupole-orbitrap-MS in targeted LC-MS determinations of small molecules显示文摘 | GRUND B MARVIN L ROCHAT B | 2016 | J Pharm Biomed Anal2016，124，5： | 1 |
| 11 | Apathy and executive dysfunction in Alzheimer disease显示文摘 | Esposito F Rochat L Van der Linden AC | 2010 | Alzheimer Dis Assoc Disord2010，24，： | 1 |
| 12 | The role of urgency and its underlying psychological mechanisms in problematic behaviours 显示文摘 | BILLIEUX J GAY P ROCHAT L | 2010 | Behav Res Ther2010，48，11： | 1 |
| 13 | The role of im- pulsivity in actual and problematic use of the mobile phone 显示文摘 | Billieux J Van Der Linden M Rochat L | 2008 | Applied Cognitive Psychology2008，22，9： | 1 |
| 14 | The role of impulsivity in actual and problematic use of the mobile phone显示文摘 | BILLIEUX J VAN DER LINDEN M ROCHAT L | 2008 | Applied Cognitive Psychology2008，22，9： | 1 |
| 15 | Human CYP2B6: expression, inducibility and catalytic activities显示文摘 | Gervot L Rochat B Gautier JC | 1999 | Phamaacogenetics1999，9，3： | 1 |
| 16 | The Role of Impulsivity in Actual and Problematic Use of the Mo bile Phone 显示文摘 | BILLIEUX J VAN DER LINDEN M ROCHAT L | 2008 | Applied Cognitive Psychology2008，22，9： | 1 |
| 17 | Intragastric administration of a superoxide dismutase-producing recombinant Lactobacillus casei BL23 strain attenuates DSS colitis in mice显示文摘 | WATTERLOT L ROCHAT T SOKOL H | 2010 | Int J Food Microbiol2010，144，1： | 1 |
| 18 | Sequentially evolved bilateral epidural haematomas显示文摘 | Rochat P Johannesen H H Poulsgard L | 2002 | Clin Neurol Neurosurg2002，105，1： | 1 |
| 19 | Sequentially evolved bilateral epidural haematomas显示文摘 | Rochat P Johannesen HH Poulsgard L | 2002 | Clini Neurol Neurosurg2002，105，1： | 1 |
| 20 | The role of impulsivity inac- tual and problematic use of the mobile phone显示文摘 | Billieux J Van der Linden M Rochat L | 2008 | Appl Cognit Psyehol2008，22，9： | 1 |
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