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| 1 | Identification and characterization of genes that control fat deposition in chickens显示文摘Background: Fat deposits in chickens contribute significantly to meat quality attributes such as juiciness, flavor,taste and other organoleptic properties. The quantity of fat deposited increases faster and earlier in the fastgrowing chickens than in slow-growing chickens. In this study, Affymetrix Genechip? Chicken Genome Arrays 32773transcripts were used to compare gene expression profiles in liver and hypothalamus tissues of fast-growing and slow-growing chicken at 8 wk of age. Real-time RT-PCR was used to validate the differential expression of genes selected from the microarray analysis. The mRNA expression of the genes was further examined in fat tissues. The association of single nucleotide polymorphisms of four lipid-related genes with fat traits was examined in a F2resource population.Results: Four hundred genes in the liver tissues and 220 genes hypothalamus tissues, respectively, were identified to be differentially expressed in fast-growing chickens and slow-growing chickens. Expression levels of genes for lipid metabolism(SULT1B1, ACSBG2, PNPLA3, LPL, AOAH) carbohydrate metabolism(MGAT4B, XYLB, GBE1, PGM1,HKDC1)cholesttrol biosynthesis(FDPS, LSS, HMGCR, NSDHL, DHCR24, IDI1, ME1) HSD17B7 and other reaction or processes(CYP1A4, CYP1A1, AKR1B1, CYP4V2, DDO) were higher in the fast-growing White Recessive Rock chickens than in the slow-growing Xinghua chickens. On the other hand, expression levels of genes associated with multicellular organism development, immune response, DNA integration, melanin biosynthetic process, muscle organ development and oxidation-reduction(FRZB, DMD, FUT8, CYP2C45, DHRSX, and CYP2C18) and with glycol-metabolism(GCNT2, ELOVL 6, and FASN), were higher in the XH chickens than in the fast-growing chickens. RT-PCR validated high expression levels of nine out of 12 genes in fat tissues. The G1257069A and T1247123C of the ACSBG2 gene were significantly associated with abdominal fat weight. The G4928024A of the FASN gene were significantly associated with fat bandwidth, and abdominal fat percentage. The C4930169T of the FASN gene was associated with abdominal fat weight while the A59539099G of the ELOVL 6 was significantly associated with subcutaneous fat. The A8378815G of the DDT was associated with fat band width.Conclusion: The differences in fat deposition were reflected with differential gene expressions in fast and slow growing chickens. | Hirwa Claire D'Andre Wallace Paul Xu Shen Xinzheng Jia Rong Zhang Liang Sun Xiquan Zhang | 2014 | Journal of Animal Science and Biotechnology2014，5，1： | 7 |
| 2 | 中年成人平均动脉压的体位改变与动脉硬度的关系:Framingham心脏研究显示文摘Torjesen A, Cooper LL, Rong J, Larson MG, Hamburg NM, Levy D, Benjamin EJ, Vasan RS, Mitchell GF. Relations of arterial stiffness with postural change in mean arterial pressure in middle-aged adults:the Framingham heart study. Hyperten- sion,2017,69(4) :685-690.站立位血压稳定调节受损可导致不良结果,包括跌倒、晕厥和定向障碍。平均动脉压(meanarterialpressure,MAP)通常在站立位时增加,然而,站立位MAP增加不足或减少可能导致脑灌注减少。已有研究报道,在动脉硬度增加的老年人中存在体位性低血压,年轻至中年人MAP的体位性改变与动脉硬度的相关性尚未阐明。该研究分析了Framingham心脏研究第3代队列中的受试者3205人(女性1693人,占53%)的直立性血压反应和全面血液动力学数据。 | Torjesen A Cooper LL Rong J Larson MG Hamburg NM Levy D Benjamin EJ Vasan RS Mitchell GF 刘莉 叶鹏 | 2017 | 中华高血压杂志2017，25，3： | 5 |
| 3 | Characteriztions of the Benson proper efficiency for nonconvex vector optimization显示文摘 | CHEN G Y RONG W D | 1998 | Journal of Optimization Theory and Applications1998，98，2： | 1 |
| 4 | Ligands Dominate Highly Syndioselective Polymerization of Styrene by Using Constrained-geometry-configuration Rare-earth Metal Precursors显示文摘 | Pan Y P Rong W F Cui D M | | 0，，03： | 1 |
| 5 | Impact of Copula Selection on Geotechnical Reliability under Incomplete Probability Information显示文摘 | TANG X LI D RONG G | 2013 | Computers and Geotechnics2013，49，： | 1 |
| 6 | ε-Weak Minimal Solutions of Vector Optimization Problems with Set-valued Maps显示文摘 | Rong W D Wu Y N | 2000 | Journal of Optimization Theory and Applications2000，106，3： | 1 |
| 7 | Connective tissue growth tactor antibody therapy attenuates hyperoxia-induced lung injury in neonatal rats显示文摘 | Alapati D Rong M Chen S | 2011 | Am J Respir Cell Mol Biol2011，45，6： | 1 |
| 8 | Signalling mechanisms underlying the morphological responses of the root system to nitrogen in Arabidopsis thaliana显示文摘 | Zhang H Rong H Pilbeam D | 2007 | J Exp Bot2007，58，9： | 1 |
| 9 | Evaluation of over 100 scanner-years of computed tomography daily quality control data显示文摘 | NUTE J L RONG J STEVENS D M | 2013 | Med Phys2013，40，05： | 1 |
| 10 | Minimally invasive liver resection for huge(≥10cm)tumors:an international multicenter matched cohort study with regression discontinuity analyses显示文摘Background:The application and feasibility of minimally invasive liver resection(MILR)for huge liver tumours(≥10 cm)has not been well documented.Methods:Retrospective analysis of data on 6,617 patients who had MILR for liver tumours were gathered from 21 international centers between 2009-2019.Huge tumors and large tumors were defined as tumors with a size≥10.0 cm and 3.0-9.9 cm based on histology,respectively.1:1 coarsened exact-matching(CEM)and 1:2 Mahalanobis distance-matching(MDM)was performed according to clinically-selected variables.Regression discontinuity analyses were performed as an additional line of sensitivity analysis to estimate local treatment effects at the 10-cm tumor size cutoff.Results:Of 2,890 patients with tumours≥3 cm,there were 205 huge tumors.After 1:1 CEM,174 huge tumors were matched to 174 large tumors;and after 1:2 MDM,190 huge tumours were matched to 380 large tumours.There was significantly and consistently increased intraoperative blood loss,frequency in the application of Pringle maneuver,major morbidity and postoperative stay in the huge tumour group compared to the large tumour group after both 1:1 CEM and 1:2 MDM.These findings were reinforced in RD analyses.Intraoperative blood transfusion rate and open conversion rate were significantly higher in the huge tumor group after only 1:2 MDM but not 1:1 CEM.Conclusions:MILR for huge tumours can be safely performed in expert centers It is an operation with substantial complexity and high technical requirement,with worse perioperative outcomes compared to MILR for large tumors,therefore judicious patient selection is pivotal. | Tan-To Cheung Xiaoying Wang Mikhail Efanov Rong Liu David Fuks Gi-Hong Choi Nicholas LSyn Charing CChong Iswanto Sucandy Adrian KHChiow Marco VMarino Mikel Gastaca Jae Hoon Lee TPeter Kingham Mathieu D’Hondt Sung Hoon Choi Robert PSutcliffe Ho-Seong Han Chung Ngai Tang Johann Pratschke Roberto ITroisi Brian KPGoh International Robotic and Laparoscopic Liver Resection Study Group Collaborators | 2021 | Hepatobiliary Surgery and Nutrition2021，10，5： | 1 |
| 11 | ε-weak minimal solutions of vector optimiaztion problems with set-valued maps显示文摘 | RONG W D WU Y N | 2000 | Journal of Optimization Theory and Applications2000，106，3： | 1 |
| 12 | Impact of Copulas election on geotechnical reliability under incomplete probability information显示文摘 | TANG X S LI D Q RONG G | 2013 | Computers and Geotechnics2013，49，： | 1 |
| 13 | Efficient Margin-Based Rank Leaming Algorithms for Information Retrieval显示文摘 | Rong Yan Alexander Hauptmann D | 2006 | CIVR2006，4071，： | 1 |
| 14 | Size-dependent chemical and - moagnetic mrdering in L10-FePt nanoparticles 显示文摘 | Rong C B Li D Vikas N | 2006 | Adv Mater2006，18，： | 1 |
| 15 | Nonlinear process monitoring based on maximum variance unfolding projections 显示文摘 | Shao J D Rong G | 2009 | Expert Systems with Applications2009，36，11： | 1 |
| 16 | BA Y 439006 exhibits broad spec?trum oral antitumor activity and targets the RAF / MEK/ERK pathway and receptor tyrosine kinases in?volved in tumor progression and angiogenesis显示文摘 | Wilhelm S M Carter C Tang L Wilkie D McNabola A Rong H | 2004 | Cane?er Res2004，64，70： | 1 |
| 17 | Investigation of the effect of type 2 diabetes mellitus on subgingival plaque microbiota by high -throughput 16S rDNA pyrosequeneing 显示文摘 | Zhou M Rong R Munro D | 2013 | PLoS One2013，228，61： | 1 |
| 18 | Synthesis and characterization of a novel nano-scale magnetic solid base catalyst involving a layered double hydroxide supported on a ferrite core显示文摘 | ZHANG Hui QI Rong EVANS D G | 2004 | J Solid State Chem2004，177，： | 1 |
| 19 | Characterizations of super efficicncy in conecomexlike vector optimization with set-valued maps显示文摘 | RONG W D WU Y N | 1998 | Math Meth OperRes1998，，48： | 1 |
| 20 | Fuzzy comprehensive evaluation on the quality of different mixed feeds for fattening lambs by using in vitro method 显示文摘 | SHENG G X RONG D W GUO H J | 2008 | Livestock Science2008，2，3： | 1 |
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