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| 1 | Association between polymorphisms of APE1 and OGG1 and risk of colorectal cancer in Taiwan显示文摘AIM: To evaluate the effects of OGG1(Ser326Cys, 11657A/G, and Arg154His) and APE1(Asp148Glu, and T-656G) polymorphisms on colorectal cancer(CRC) risk.METHODS: We enrolled 727 cases newly diagnosed with colorectal adenocarcinoma and 736 age- and sex-matched healthy controls from a medical center in Taiwan. Genomic DNA isolated from the buffy coat was used for genotyping through polymerase chain reaction. Unconditional logistic regressions were used for calculating ORs and 95%CIs to determine the association between the genetic polymorphisms and CRC risk. Haplotype frequencies were estimated using PHASE software. Moreover, stratification analyses onthe basis of sex, age at diagnosis, and tumor subsite and stage were performed.RESULTS: The CRC risk was higher in patients with the OGG1 326Ser/Cys + Cys/Cys genotype(OR = 1.38, 95%CI: 1.03-1.85, P = 0.030), particularly high in patients with stage Ⅲ + Ⅳ cancer(OR = 1.48, 95%CI: 1.03-2.13) compared with patients with the Ser/Ser genotype. In addition, OGG1 11657 G allele carriers had a 41% reduced CRC risk among stage 0-Ⅱ patients(OR = 0.59, 95%CI: 0.35-0.98). The CRC risk was significantly higher among females with the APE1 Glu allele(OR = 1.41, 95%CI: 1.02-1.96). The APE1 148Glu/-656 G haplotype was also associated with a significant CRC risk in females(OR = 1.36, 95%CI: 1.03-1.78).CONCLUSION: OGG1 and APE1 polymorphisms are associated with stage- and sex-specific risk of CRC in the Taiwan Residents population. | Ching-Yu Lai Ling-Ling Hsieh Reiping Tang Regina M Santella Chung Rong Chang-Chieh Chih-Ching Yeh | 2016 | World Journal of Gastroenterology2016，22，12： | 7 |
| 2 | Responses of Contrasting Rice (Oryza sativa L.) Genotypes to Salt Stress as Affected by Nutrient Concentrations显示文摘The study was conducted to investigate the effects of applying different concentrations of the macronutrients K+,Ca2+,and Mg2+ on the responses of contrasting rice(Oryza sativa L.) genotypes under salt stress.A solution culture experiment was conducted in a phytotron at the International Rice Research Institute(IRRI),under controlled temperature and humidity and natural sunlight.When subjected to salt stress of 100 mmol L-1 using NaCl,the salt tolerant genotypes FL478 and IR651,accumulated less Na+ and maintained lower ratios of Na+/K+,Na+/Ca2+,and Na+/Mg2+ than the sensitive genotypes IR29 and Azucena.These tolerant genotypes also had higher concentrations of K+ in their shoots and greater root and shoot biomass and green leaf area.Tolerant genotypes also maintained much lower concentration of Na+ and lower and more favorable ratios of Na+/K+,Na+/Ca2+,and Na+/Mg2+ in their active and developing tissues.Salt tolerance and shoot and root growth of both tolerant and sensitive genotypes were enhanced considerably when higher concentrations of Ca2+ and Mg2+ were applied in culture solution.The concentration of Na+ and the ratios of Na+/K+,Na+/Ca2+,and Na+/Mg2+ in shoots also declined significantly.The beneficial effects of higher calcium were greater than that of magnesium and application of higher concentration of K+ seems to have minor effects.Responses to salinity in rice can therefore be considerably enhanced through proper nutrient management,by increasing the concentrations of nutrient elements that have favorable effects such as Ca2+ and Mg2+.Calcium is particularly more effective than both magnesium and potassium,and can be applied at relatively larger quantities in salt affected soils. | ZHANG Zhen-hua LIU Qiang SONG Hai-xing RONG Xiang-min Abdelbagi M Ismail | 2011 | Agricultural Sciences in China2011，10，2： | 3 |
| 3 | Synthesis of silver nanoparticles and their self-organization behavior in epoxy resin 显示文摘 | Rong M Z Zhang M Q | 1999 | Polymer1999，40，： | 2 |
| 4 | Numerical modeling of arc root transfer during contact opening in a low voltage air circuit breaker 显示文摘 | YI W RONG M Z YANG F | 2008 | IEEE Transactions2008，，： | 1 |
| 5 | A comparative study of nanosilica/poly(propylene) composites prepared by reactive compatibilization 显示文摘 | Chen J H Rong M Z Ruan W H Mai Y L Zhang M Q | 2008 | Macromolecular Chemistry and Physics2008，209，： | 1 |
| 6 | Automated variable weighting in K-means type clustering 显示文摘 | HUANG J Z NG M K RONG Hong-qiang | 2005 | IEEE Trans on Pattern Analysis and Machine Intelligence2005，27，5： | 1 |
| 7 | Improvement of tensile properties of nano-SiO2/PP composites in relation to percolation mechanism 显示文摘 | Rong M Z Zhang M Q Zheng Y X | 2001 | Polymer2001，42，7： | 1 |
| 8 | Improvement of tensile properties of nano-SiO2/PP composites in relation to percolation mechanism 显示文摘 | RONG M Z ZHANG M Q ZHENG Y X | 2001 | Polymer2001，42，7： | 1 |
| 9 | Development of a finite element analysis tool for fixture design integrity verification and optimization 显示文摘 | Amaral N Rencis J J Rong Y M | 2005 | The International Journal of Advanced Manufacturing Technology2005，25，5： | 1 |
| 10 | Catalytic oxidation of alcohols by a novel copper Schiff base ligand derived from acetylacetonate and L-leucine in ionic liquids显示文摘 | RONG M Z LIU C HAN J Y | 2008 | Catal Lett2008，125，： | 1 |
| 11 | An Optimisation Approach for Managing Fresh Food Quality throughout the Supply Chain 显示文摘 | Rong A Akkerman R Crunow M | 2011 | International Journal of Production Economics2011，131，1： | 1 |
| 12 | Ligands Dominate Highly Syndioselective Polymerization of Styrene by Using Constrained-geometry-configuration Rare-earth Metal Precursors显示文摘 | Pan Y P Rong W F Cui D M | | 0，，03： | 1 |
| 13 | Application of alkoxyamine in self-healing of epoxy显示文摘 | YUAN C E ZHANG M Q RONG M Z | 2014 | Journal of Materials Chemistry A2014，2，： | 1 |
| 14 | A transient receptor potential channel expressed in taste receptor cells显示文摘 | Perez CA Huang L Rong M | 2002 | Nat Neurosci2002，5，： | 1 |
| 15 | Static and dynamic analysis for contactor with a new type of permanent magnet actuator显示文摘 | Rong M Z Lou J Y Liu Y Y | 2006 | IEICE Transactions on Electronics2006，89，8： | 1 |
| 16 | Calculation of electric and magnetic fields in simplified chambers of low voltage circuit breakers 显示文摘 | WU Y RONG M Z LI J | 2006 | IEEE Transactions2006，，： | 1 |
| 17 | Effects of reactive compatibilization on the performance of nano-silica filled polypropylene composites 显示文摘 | Zhou H J Rong M Z Zhang M Q Friedrich K | 2006 | Journal of Materials Science2006，41，： | 1 |
| 18 | Met expression and sarcoma tumorigenicity显示文摘 | Rong S Jeffers M Resau JH | 1993 | Cancer Res1993，53，22： | 1 |
| 19 | Atomic force microscopy study on structure and properties of irradiation grafted silica particles in polypropylene-based nanocomposites 显示文摘 | ZHANG M Q RONG M Z ZENG H M | 2001 | J Appl Polym Sci2001，80，12： | 1 |
| 20 | Spectrum partition and relay positioning for cellular system enhanced with two-hop fixed relay nodes显示文摘 | LI P RONG M XUE Y | 2007 | IEICE Transactions on Communications2007，90，11： | 1 |
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