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| 1 | Radioembolization for the treatment of unresectable hepatocellular carcinoma:A clinical review显示文摘Hepatocellular carcinoma(HCC)is the sixth most common cancer in the world.The majority of patients with HCC present with unresectable disease.These patients have historically had limited treatment options secondary to HCC demonstrating chemoresistance to the currently available systemic therapies.Additionally, normal liver parenchyma has shown intolerance to tumoricidal radiation doses,limiting the use of external beam radiation.Because of these limitations,novel percutaneous liver-directed therapies have emerged. The targeted infusion of radioactive microspheres (radioembolization)represents one such therapy. Radioembolization is a minimally invasive transcatheter therapy through which radioactive microspheres are infused into the hepatic arteries that supply tumor. Once infused,these microspheres traverse the hepatic vascular plexus and selectively implant within the tumor arterioles.Embedded within the arterioles, the 90Y impregnated microspheres emit high energy and low penetrating radiation doses selectively to the tumor.Radioembolization has recently shown promise for the treatment of patients with unresectable HCC. The objective of this review article is to highlight twocurrently available radioembolic devices(90Y,188Rh)and provide the reader with a recent review of the literature. | Saad M Ibrahim Robert J Lewandowski Kent T Sato Vanessa L Gates Laura Kulik Mary F Mulcahy Robert K Ryu Reed A Omary Riad Salem | 2008 | World Journal of Gastroenterology2008,14,11: | 14 |
| 2 | Diffusion-weighted magnetic resonance imaging to predict response of hepatocellular carcinoma to chemoembolization显示文摘AIM: To investigate whether intra-procedural diffusion- weighted magnetic resonance imaging can predict response of hepatocellular carcinoma (HCC) during trans- catheter arterial chemoembolization (TACE). METHODS: Sixteen patients (15 male), aged 59 ±11 years (range: 42-81 years) underwent a total of 21 separate treatments for unresectable HCC in a hybrid magnetic resonance/interventional radiology suite. Ana- tomical imaging and diffusion-weighted imaging (b = 0, 500 s/mm2) were performed on a 1.5-T unit. Tumor enhancement and apparent diffusion coefficient (ADC, mm2/s) values were assessed immediately before and at 1 and 3 mo after TACE. We calculated the percent change (PC) in ADC values at all time points. We compared follow-up ADC values to baseline values using a paired t test (α = 0.05). RESULTS: The intra-procedural sensitivity, specificity, and positive and negative predictive values (%) for detecting a complete or partial 1-mo tumor response using ADC PC thresholds of ±5%, ±10%, and ±15% were 77, 67, 91, and 40; 54, 67, 88, and 25; and 46, 100, 100, and 30, respectively. There was no clear predictive value for the 3-mo follow-up. Compared to baseline, the immediate post-procedure and 1-mo mean ADC values both increased; the latter obtaining statistical significance (1.48 ± 0.29 mm2/s vs 1.65 ± 0.35 × 10-3 mm2/s, P < 0.014). CONCLUSION: Intra-procedural ADC changes of > 15% predicted 1-mo anatomical HCC response with the greatest accuracy, and can provide valuable feedback at the time of TACE. | Johnathan C Chung Neel K Naik Robert J Lewandowski Mary F Mulcahy Laura M Kulik Kent T Sato Robert K Ryu Riad Salem Andrew C Larson Reed A Omary | 2010 | World Journal of Gastroenterology2010,16,25: | 13 |
| 3 | Damage identification in beam-type structures: frequency-based method vs mode-shape-based method 显示文摘 | Kim J T Ryu Y S Cho H M | 2003 | Engineering Structures2003,25,1: | 2 |
| 4 | On sinterability of Cu-coated W nanocomposite powder prepared by a hydrogen reduction of a high-energy ball-milled WO3-CuO mixture 显示文摘 | RYU S S PARK H R KIM H T | 2012 | Journal of Materials Science2012,47,20: | 1 |
| 5 | How to quantify tree leaf area index in an open savanna ecosystem: a multi-instrument and multi-model approach显示文摘 | Ryu Y Sonnentag O Nilson T | 2010 | Agricultural and Forest Meteorology2010,150,1: | 1 |
| 6 | Improvement of silicon powder negative electrodes by copper electroless deposition for lithium secondary batteries显示文摘 | KIM J W RYU J H LEE K T OH S M | 2005 | J Power Sources2005,147,: | 1 |
| 7 | A generalized approach to the modification of solid surfaces显示文摘 | Ryu D Y Shin K Drockenmuller K Hawker C J Russell T P | 2005 | Science2005,308,: | 1 |
| 8 | Synthesis, sintering and mechanical properities of nanocrystailline cemented tungste carbide-A review 显示文摘 | FANG Z Z WANG X RYU T HWANG K S SOHN H Y | 2009 | International Journal of Refractory Metals & Hard Materials2009,27,: | 1 |
| 9 | Photocatalytic production of hydrogen from water with visible light using hybrid catalysts of CdS attached to microporous and mesoporous silicas显示文摘 | Ryu S Balcerski W Lee T K | | 0,,49: | 1 |
| 10 | Measurement and analysis of thermal stresses in 3D integrated structures containing through-silicon-vias显示文摘 | JIANG T F RYU S K ZHAO Q | 2013 | Microelectronics Reliability2013,53,1: | 1 |
| 11 | Long-term course of cognitive function in chronically hospitalized patients with schizophrenia transitioning to Community-based living显示文摘 | Nemoto T Niimura H Ryu Y | 2014 | Schizoph Res2014,155,13: | 1 |
| 12 | Fabrication ofSuperhydrophobic Surface from a Supramolecular Or-ganosilane with Quadruple Hydrogen Bonding显示文摘 | HAN J T LEE D H RYU C Y | 2004 | Journal of the American Chemical Society2004,126,: | 1 |
| 13 | Evaluation of funda- mental UHPC properties according to the shape of steel fiber显示文摘 | Ryu G S Kang S T Park J J | 2011 | Key Eng Mater2011,,: | 1 |
| 14 | The Mechanical Properties of Fly Ash-based Geopolymer Concrete with Alkaline Activators显示文摘 | Ryu G S Lee Y B Koh K T | 2013 | Construction and Building Materials2013,47,: | 1 |
| 15 | Fabrication of superhydrophobic surface from a supramolecular organosilane with quadruple hydrogen bonding显示文摘 | Han J T Lee D H Ryu C Y Cho K | 2004 | J Am Chem Soc2004,126,15: | 1 |
| 16 | Individual variation in susceptibility to extracranial carotid atherosclerosis显示文摘 | Rubens J Espeland MA Ryu T | 1988 | Arterioclerosis1988,8,4: | 1 |
| 17 | Digital CMOS IC's in 6H-SiC operating on a 5V power supply显示文摘 | Ryu S H Kornegay K T Cooper J A Jr | 1998 | IEEE Trans Electron Devices1998,45,1: | 1 |
| 18 | Damage identification in beam-type structures:Frequency-based method vs mode- shape-based method 显示文摘 | Kim J T Ryu Y S Cho H M | 2003 | Eng Struct2003,25,1: | 1 |
| 19 | A case of myxoid liposarcoma of the breast显示文摘 | Saito T Ryu M Fukumura Y | 2013 | Int J Clin Exp Pathol2013,6,7: | 1 |
| 20 | Photocatalytic production of hydrogen from water with visible light using hybrid catalysts of CdS attached to microporous and mesoporous silicas 显示文摘 | Ryu S Y Balcerski W Lee T K | 2007 | The Journal of Physical Chemistry C2007,111,18: | 1 |