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1系统性药物治疗儿童银屑病的安全性显示文摘银屑病是一种常见的慢性炎症性皮肤病。成年人的发病率为2%~3%,其中大约有三分之一的患者在18岁之前发病。在儿童期,该病的发病率呈线性增长。从1970年至2000年,儿童银屑病的发病率增加了一倍多。尽管对许多轻度银屑病患儿而言,局部治疗已足够,但对更多可能影响生活质量的重度或顽固性的银屑病患儿,则往往需要系统性治疗。bronckers imgj seyger mmb west dp lara-corrales i tollefson m tom wl hogeling m belazarian l zachariae c mahé e siegfried e philipp s szalai z vleugels ra holland k murphy r baselga e cordoro k lambert j alexopoulos a mrowietz u kievit w paller as 邓婕(编译) 张锡宝(审校) 2017皮肤性病诊疗学杂志2017,24,5:3
2卒中介入治疗培训指南:国际多学会共识文件显示文摘1背景 缺血性卒中是全球人口死亡和残疾的首要原因。很多急性大血管闭塞(emergent large vesselocclusion,ELVO)患者都会遗留长期残疾。事实上,这些颅内大动脉闭塞经常会导致大面积脑损伤,进而造成患者死亡或严重致残。Lavine SD Cockroft K Hoh B Bambakidis N Khalessi AA Woo H Riina H Siddiqui A Hirsch JA Chong W Rice H Wenderoth J Mitchell P Coulthard A Signh TJ Phatorous C Khangure M Klurfan P ter Brugge K Iancu D Gunnarsson T Pongpech S Rodesch G Soderman M Taylor A Krings T Orbach D Picard L Suh DC Zheng HQ Jansen O Muto M Szikora I Pierot L Brouwer P Gralla J Renowden S Andersson T Fiehler J Turjman F White P Januel AC Spelle L Kulcsar Z Chapot R Biondi A Dima S Taschner C Szajner M Krajina A Sakai N Matsumaru Y Yoshknura S Ezura M Fujinaka T Iihara K Ishii A Higashi T Hirohata M Hyodo A Ito Y Kawanishi M Kiyosue H Kobayashi E Kobayashi S Kuwayama N Matsumoto Y Miyachi S Murayama Y Nagata I Nakahara I Nemoto S Niimi Y Oishi H Satomi J Satow T Sugiu K Tanaka M Terada T Yamagami H Diaz O Lylyk P Jayaraman MV Patsalides A Gandhi CD Lee SK Abruzzo T Albani B Ansari SA Arthur AS Baxter BW Bulsara KR Chen M Almandoz JE Fraser JF Heck DV Hetts SW Hussain MS Klucznik RP Leslie-Mawzi TM Mack WJ McTaggart RA Meyers PM Mocco J Prestigiacomo CA Pride GL Rasmussen PA Starke RM Sunenshine PJ Tarr RW Frei DF Pabo M Nogueira RG Zaidat OO Jovin T Linfante I Yavagal D Liebeskind D Novakovic R Pongpech S 许岩 孙瑞 郭芮兵 2017国际脑血管病杂志2017,25,5:2
3Detection of prostatic specific membrance antigen messager RNA using immunobead reverse transcriptase polymerase chain reaction显示文摘Ghossein RA Osman I Bhattacharya S 1999Diagn Mol Pathol1999,8,2:2
4Inherited susceptibility to lung cancer may be associated with the T790M drug resistance mutation in EGFR显示文摘Bell DW Gore I Okimoto RA 2005Nat Genet2005,37,12:1
5MMP-2 and MMP-9 type Ⅳ collagenases in colorectal cancer显示文摘 Talbot I Smith RA 1996Cancer Res1996,56,1:1
6Canopy temperature depression association with yield of irrigated spring wheat cultivars in a hot climate显示文摘AMANI I FISCHER RA REYNOLDS MP 1996Agricluture Crop Science1996,,:1
7Association between calcium ingested from drinking water and femoral bone density in elderly women : evidence from the EPIDOS cohort 显示文摘Aptel I Cance RA Grandjean H 1999J Bone Miner Res1999,14,5:1
8Detection of prostatic specific membrane antigen messenger RNA using immunobead reverse transcriptase polymerase chain reaction显示文摘Ghossein RA Osman I Bhattacharya S 1999Diagn Mol Pathol1999,8,2:1
9Exlx sion and redifferentiation of chondrocytes from osteoarthritic cartilage: cells for human cartilage tissue engineering显示文摘Hsiel Bona ra ND Wu I Lin JK 2009Tissue FaN Part A2009,15,11:1
10The impact of FADS genetic variants on ω6 polyunsaturated fatty acid metabolism in African Americans显示文摘Mathias RA Sergeant S Ruezinski I 2011BMC Genet2011,5,20:1
11A classification o{ the edentulous jaws显示文摘Cawood J I Howell RA 1988IntemationalJoumal of Oral and Maxillofacial Surgery1988,17,4:1
12Prognosis of breast cancer evidence for interaction between C-erbB-2 overexpression and mumber of involved axillary lymph nodes 显示文摘12,Mittrz I Redkar AA Badwe RA 1995J Surg1995,60,2:1
13Does spinal kyphotic deformity influence the biomechanical characteristics of the adjacent motion segments? an in vivo animal model显示文摘Oda I Cunningham BW Buckley RA 1999Spine1999,24,20:1
14The molecular basis of oculocutaneous albinism type 1 ( OCA1 ) : sorting failure and degradation of mutant tyrosinases results in a lack of pigmentation 显示文摘TOYOFUKU K WADA I SPRITZ RA 2001Biochem J2001,355,2:1
15The future of platelet function testing to guide therapy in clopidogrel low and enhanced responders显示文摘Bernlochner I Byrne RA Kastrati A 2011Expert Rev Cardiovasc Ther2011,9,8:1
16Comparative study of clinical grade human tolerogenic dendritic cells显示文摘Naranjo-Gómez M Ra(i)ch-Regué D O(n)ate C 0,,:1
17GEM-2:A new multifrequency electro- magnetic sensor显示文摘Won I J Keiswetter D A Fields G RA and Sutton L C 1996Journal of Environmental and Engineering Geophysics1996,1,2:1
18Cystic renal cancers: CT characteristics显示文摘Parienty RA Pradel B Parienty I 1985Radiology1985,157,3:1
19Release of periplasmic proteins of Brucella suis upon acidic shock involves the outer membrane protein Omp25显示文摘Boigegrain RA Salhi I Alvarez-Martinez MT 2004Infect Immun2004,72,10:1
20Point prevalence survey of antibiotic use in Scottish hospitals utilising the Glasgow Anti- microbial AuditTool (GAAT)显示文摘Seaton RA Nathwani I) Burton P 2007Int J Antimicrob Agents2007,29,6:1
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