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| 1 | 一种房颤风险评分系统的建立(Framingham心脏研究):基于社区的队列研究显示文摘背景房颤导致了发病率和病死率的显著上升。本研究旨在建立一种预测个体罹患房颤绝对风险的风险评分系统,并提供研究人员评价新危险因素的流程。方法作者评估了Framingham心脏研究中于1968年6月至1987年9月间进行了8044次检测的4764例参与者(55%为女性,年龄45~95岁)。此后,参与者被随访至房颤首发,随访期最长达10年。多变量Coxi回归确认出1(1年内罹患房颤的临床危险因素。次级分析纳入了常规超声心动图检测指标(5152例4参与者,7156次检测)对房颤风险进行再分层评估,并评价超声检测指标能否提高风险预测能力。结果4764例参与者中的457例4(10%)罹患房颤。年龄、性别、体重指数、收缩压、降压治疗、PR间期、有临床意义的心脏杂音及心力衰竭与房颤相关,并被纳入了风险评分模型(除体重指数P=0.08外,其余均为P〈0.05),模型的C统计量为0.78(95%CI0.76~0.80)。10年房颤风险随年龄变化:年龄〈65岁的人群中53例(1%)风险高于15%,而〉65岁的人群中为783例(27%)。为提高预测能力而纳入超声检测指标仅使模型C统计量略微增高,由0.78(95%C10.75~0.80)增至0.79(95%CI0.77~0.82:P=0.005)。超声心动图检测指标并不能改善风险再分层评估(P=0.18)。结论基于社区医疗中易得的临床因素建立的风险评分系统,有助于确认社区个体罹患房颤的风险,评估技术或标志物能否改善风险预测,以及针对高危个体采取预防措施。 | Renate B Schnabel Lisa M Sullivan Daniel Levy Michael J Pencina Joseph M Massaro Ralph B D'Agostino Sr Christopher Newton-Cheh Jennifer F Yamamoto Jared W Magnani Thomas M Tadros William B Kannel Thomas J Wang Patrick T Ellinor Philip A Wolf Ramachanclran S Vasan Emelia J Benjamin 黄刚(译) | 2009 | 世界临床医学2009，，9： | 2 |
| 2 | Characterization of commercially available lithium-ion batteries显示文摘 | Bradley A J Ralph E W | 1998 | J Power Sources1998，70，1： | 1 |
| 3 | On the role of revenue-sharing contracts in supply chains显示文摘 | Harish K Ralph A W | 2011 | Operations Research Letters2011，39，1： | 1 |
| 4 | Cytokines, insulin-like growth factor 1, sarcopenia, and mortality in very old community-dwelling men and women: the Framingham Heart Study显示文摘 | Ronenn Roubenoff Helen Parise Hélène A Payette Leslie W Abad Ralph D’Agostino Paul F Jacques Peter W.F Wilson Charles A Dinarello Tamara B Harris | 2003 | The American Journal of Medicine2003，，6： | 1 |
| 5 | Age of drinking onset and unin- tentional injury involvement after drinking 显示文摘 | Ralph W Heeren T Jamamka A | 2000 | JAMA2000，1284，： | 1 |
| 6 | Assessment of pholosynthetic performance of Prochloron in Lissoclinum patella in hosplte by chlorophyll fluorescence measurements显示文摘 | Schreiber U Gademann R Ralph P J Larkum A W D | 1997 | PI Ceil Physiol1997，38，： | 1 |
| 7 | Aniche for cyanobacteria containing chlorophyll d 显示文摘 | Kuhl M Chen M Ralph P J Larkum A W D | 2005 | Nature2005，433，： | 1 |
| 8 | Past and Projected Rural Land Conversion in the US at State, Regional, and National Levels显示文摘 | ERIC M W ANITA T M RALPH J A | 2009 | Landscape and Urban Planning2009，89，1： | 1 |
| 9 | Assessment of Photosynthetic Performance of Prochloron in Lissoclinum patella in hospite by Chlorophyll Fluorescence Measurements显示文摘 | Schreiber U Gademann R Ralph P J Larkum A W D | 1997 | Plant & Cell Physiology1997，38，： | 1 |
| 10 | IMD-0354 targets breast cancer stem cells: a novel approach for an adjuvant to chemotherapy to prevent muhidrug resistance in a murine mod- el显示文摘 | GOMEZ-CABRERO A WOLFGANG W RALPH AR | 2013 | Plas One2013，8，73： | 1 |
| 11 | Selectively increased growth of fetal hemoglobin-expressing adult erythroid progenitors after brief treatment of early progenitors with transforming growth factor beta显示文摘 | Ralph M Bohmer Thomas A Campbell Diana W Bianchi | 2000 | Blood2000，95，9： | 1 |
| 12 | Spatial heterogeneity in active chlorophyll fluorescence and PSII activity of coral tissues 显示文摘 | Ralph P J Gademann R Larkum A W D | 2002 | Marine Biology2002，141，4： | 1 |
| 13 | On the role of revenue-sharing contracts in supply chains显示文摘 | Harish K Ralph A W | 2011 | Operations Research Letters2011，39，1： | 1 |
| 14 | A correction to the algo- rithm in Reiter's theory of diagnosis显示文摘 | Russell G Barbara A S Ralph W W | 1989 | Artificial Intelligent1989，41，1： | 1 |
| 15 | Prediction of coronary heart disease using risk factor categories显示文摘 | Peter WF W Ralph BD A Daniel L | 1998 | Circulation1998，97，18： | 1 |
| 16 | White locoweed toxici':y is facilitated by a fungal endophyte and nitrogen-fixing bacteria 显示文摘 | Valdez Barillas J R Paschkel M W Ralphs M H et a l | 2007 | Ecology2007，5，7： | 1 |
| 17 | Capacity fade mechanisms and side reactions in lithium-ion batteries显示文摘 | Pankaj A Ralph E W Marc D | 1998 | J Electrochem Soc1998，145，10： | 1 |
| 18 | Influence of some design variables on the thermal behavior of a lithium-ion cell显示文摘 | Gerardine G B Bradley A J Ralph E W | 1999 | Journal of the Electrochemical Society1999，146，3： | 1 |
| 19 | Simple Scheme for Efficient Linear Optics Quantum Gates显示文摘 | RALPH T C WHITE A G MUNRO W J | 2001 | Phys Rev A2001，65，01： | 1 |
| 20 | Adescriptive analysis of STD prevalence among urban pregnant African-American teens: data from apilot study 显示文摘 | RALPH J D GINA M W RICHARD A C | 2004 | Journal of Adolescent Health2004，34，： | 1 |
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