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1篇 您的检索式：作者名="Ramon Scull"

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		题名	作者	年代	出处	被引量
	1	Antileishmanial assessment of leaf extracts from Pluchea carolinensis,Pluchea odorata and Pluchea rosea显示文摘Objective:To evaluate the antileishmanial activity of different extracts from three Cuban Pluchea species.Methods:In in vitro assays the IC₅₀was calculated in the promastigotes and amastigotes forms as cytotoxicity in murine macrophages.In leishmaniasis cutanea experiment,mortality, weight loss,lesion size and burden parasite were measured.Results:Extracts evaluated showed inhibitive effect on growing of promastigote form;however,active extracts caused a high toxicity. Ethanol and n-hexane extracts demonstrated specific antileishmanial activity.Ethanol and n-hexane extracts from Pluchea carolinensis(P.carolinensis) caused similar inhibition against amastigote form.The intraperitoneal administration of the ethanol extract of P.carolinensis at 100 mg/kg prevented lesion development compared with control groups.Conclusions:The antileishmanial experiment suggests that ethanol extracts from P.carolinensis is the most promising.Further studies are still needed to evaluate the polential of this plant as a source of new antileishmanial agents.	Marley Garcia Wilmer H Perera Ramon Scull Lianet Monzote	2011	Asian Pacific Journal of Tropical Medicine2011，4，10：	0

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