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| 1 | Difficult biliary cannulation: Historical perspective, practical updates, and guide for the endoscopist显示文摘Despite improvements in endoscopic technologies and accessories, development of advanced endoscopy fellowship programs, and advances in ancillary imaging techniques, biliary cannulation in endoscopic retrograde cholangiopancreatography(ERCP) can still be unsuccessful in up to 20% of patients, even in referral centers. Once cannulation has been deemed to be difficult, the risk of post-ERCP pancreatitis and technical failure inherently increases. A number of factors, including endoscopist experience and patient anatomy, have been associated with difficult biliary cannulation, but predicting a case of difficult cannulation a priori is often not possible. Numerous techniques such as pancreatic guidewire and stenting, early pre-cut, and rendezvous may be employed when standard approaches fail. Data regarding the rate of success and adverse events of these techniques have been variable, though most studies suggest that pancreatic duct stenting generally reduces the rate of post-ERCP pancreatitis in instances of difficult biliary cannulation. Here we provide a review on difficult biliary cannulation and discuss how the choice of which techniques to employ and how to best employ them should be individualized and take into account the skill of the endoscopist, the disorder being treated, the anatomy of the patient, and the available biomedical literature. | Rani Berry James Y Han James H Tabibian | 2019 | World Journal of Gastrointestinal Endoscopy2019，11，1： | 8 |
| 2 | Hemobilia: Etiology, diagnosis, and treatment显示文摘Hemobilia refers to bleeding from and/or into the biliary tract and is an uncommon but important cause of gastrointestinal hemorrhage.Reports of hemobilia date back to the 1600s,but due to its relative rarity and challenges in diagnosis,only in recent decades has hemobilia been more critically studied.The majority of cases of hemobilia are iatrogenic and caused by invasive procedures involving the liver,pancreas,bile ducts and/or the hepatopancreatobiliary vasculature,with trauma and malignancy rep-resenting the two other leading causes.A classic triad of right upper quadrant pain,jaundice,and overt upper gastrointestinal bleeding has been described(i.e.Quincke's triad),but this is present in only 25%e30%of patients with hemobilia.Therefore,prompt diagnosis depends critically on having a high index of suspicion,which may be based on a patient's clinical presentation and having recently undergone(peri-)biliary instrumentation or other predisposing factors.The treatment of hemobilia depends on its severity and suspected source and ranges from supportive care to advanced endoscopic,interventional radiologic,or surgical intervention.Here we provide a clinical overview and update regarding the eti-ology,diagnosis,and treatment of hemobilia geared for specialists and subspecialists alike. | Rani Berry James Han Ani A.Kardashian Nicholas F.LaRusso James H.Tabibian | 2018 | Liver Research2018，2，4： | 5 |
| 3 | Targeting TNF-α alpha:a novel therapeuticapp roach fo r asthma显示文摘 | Brigh tling C Berry M Am rani Y | 2008 | J A llergy Clin Immuno 12008，121，1： | 1 |
| 4 | Targeting TNF- alpha: a novel therapeutic approach for asthma 显示文摘 | Brightling C Berry M Am rani Y | 2008 | J Allergy Clm lm munol2008，121，1： | 1 |
| 5 | Targeting TNF-a alpha: a nov- el therapeutic capp roach for asthma 显示文摘 | Brightling C Berry M Am rani Y | 2008 | J Allergy Clin Im- munol2008，121，1： | 1 |
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