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| 1 | Anti-microbial principles of selected remedial plants from Southern India显示文摘Objective:To examine the anti-bacterial activity of leaf extracts of Morus alba L.(Moraceae)and Piper betel L.(Piperaceae),and seed extracts of Bombax ceiba L.(Borabacaceae).Methods:We have partially purified plant extracts by solvent extraction method,and evaluated the effect of individual fractions on bacterial growth using Escherichia coli(E.coli),Pseudomonas aeruginosa(P.aeruginosa) and Staphylococcus aureus(S.aureus) bacterial strains.Results:Compared with Morus and Bombax fractions,Piper fractions showed significant growth inhibition on all the three types of bacteria studied.The EtOAc-hexane fractions of Piper leaves exhibited significant antibacterial activity with minimum inhibitory concentrations(MIC) of 50 μg/mL culture against both gram-positive and gram-negative bacteria.The EtOAc-fractions Ⅰ,Ⅱ,and Ⅳ inhibited bacterial colony formation on soft agar in addition to growth inhibition.A combination treatment of piper fractions with ampicillin resulted in significant growth inhibition in E.coli and P.aeruginosa,and combination with anticancer drug geldanamycin(2 μg/mL) showed selective growth inhibition against P.aeruginosa and S.aureus.Three major compounds,i.e.,eugenol,3-hexene-ol and stigmasterol,were primarily identified from Piper betel leaf extractions.Among the individual compounds,eugenol treatment showed improved growth inhibition compared with stigmasterol and 3-hexene-ol.Conclusions:We are reporting potential anti-bacterial compounds from Piper betel against both gram-positive and gram-negative bacteria either alone or in combination with drug treatment. | Tirupathi Rao G Suresh Babu K J Ujwal Kumar Sujana P A Veerabhadr Raoa Sreedhar AS | 2011 | Asian Pacific Journal of Tropical Biomedicine2011，1，4： | 5 |
| 2 | Noble metal additive modulation of gas sensitivety of NaSnO3,explained by a work function based model显示文摘 | Gopal Reddy C V Manoramaa S V Raoa V J | 1999 | Thin Solid Films1999，348，： | 1 |
| 3 | Adsorptive Removal of Di-rect Azo Dye from Aqueous Phase onto Coal Based Sorbents : a Ki-netic and Mechanistic Study显示文摘 | Mohana S V Raoa N C Karthikeyan J | 2002 | Hazardous Materials2002，90，： | 1 |
| 4 | Aldol and Knoevenagel condensations catalysed by modified Mg--Al hydrotalcite: a solid base as catalyst useful in synthetic organic chemistry显示文摘 | Lakshmi Kantam M Choudary B M Koteswara Raoa Ch | 1998 | Chem Commun1998，，： | 1 |
| 5 | Morphine-sparing effect of ketoprofen after abdominal surgery 显示文摘 | RaoAS CardosaM InbasegaranK | 2000 | Anaesth Intensive Care2000，28，1： | 1 |
| 6 | A nonlinear adaptive filter for narrowband interference mitigation in spread spectrum systems显示文摘 | RAOA K D SWAMYB M N S | 2005 | IEEE Trans Commun2005，30，5： | 1 |
| 7 | Dose-dependent effects of dietary phytosterol on epithelial cell proliferation of the murine colon显示文摘 | Janezica S A Raoa A V | 1992 | Food Chem Toxicol1992，30，7： | 1 |
| 8 | Synthesis and characterization of mixed ferrite nanoparticles 显示文摘 | Raoa B E Caltunb O Choc W S | 2007 | J Magn Magn Mater2007，310，： | 1 |
| 9 | Grain refinement through arc manipulation techniques in Al-Cu alloy GTA welds显示文摘 | Raoa S R Reddyb G Kamaraja M | 2005 | Mater Sci Eng A2005，404，： | 1 |
| 10 | Analysisoflaboratory- critlcalva-luereportingatalargeacademicmedicalceterl 显示文摘 | DigheAS RaoA CoakleyAB etaL | 2006 | AmJClin Pathol2006，125，5： | 1 |
| 11 | Influence of the fuel used in the microwave synthesis of Cr2O3显示文摘 | Cherian M Raoa M S Manoharan S S | 2002 | Topics in Catalysis2002，18，34： | 1 |
| 12 | Adsorptive Removal of Direct Azo Dye fom Aqueous Phase onto Coal Based Sorbents: a Kinetic and Mechanistic Study显示文摘 | Mohana S V Raoa N C Kaheyan J | 2002 | Hazardous Materials2002，，90： | 1 |
| 13 | Morphine sparing effect of ketoprofen after abdominal surgery显示文摘 | RaoA S Cardosa M Inbasegaran K | 2000 | Anaesth Intensive Care2000，28，1： | 1 |
| 14 | Adsorptive removal of direct azo dye from aqueous phase onto coal based sorbents:a kinetic and mechanistic study 显示文摘 | Mohana S V Raoa N C Karthikeyan J | 2002 | Hazardous Materials2002，90，2： | 1 |
| 15 | Transcription factors of NF2AT family: regulation and function显示文摘 | RaoA LuoC HoganPG | 1997 | Annu Rev Immunol1997，15，： | 1 |
| 16 | Heap bioleaching of chalcopyrite: A review显示文摘 | Pradhan N Nathsarmaa K C Srinivasa Raoa K | 2008 | Minerals Engineering2008，21，5： | 1 |
| 17 | Adsorptive Removal of Direct Azo Dye from Aqueous Phase onto Coal Based Sorbents: a Kinetic and Mechanistic Study 显示文摘 | Mohana S V Raoa N C Karthikeyan J | 2002 | Hazardous Materials2002，90，： | 1 |
| 18 | Thermal characteristics of a class F fly ash显示文摘 | GANGADHARA Raoa M V B B KOLAY P K SINGH D N | 1998 | Cement and Concrete Research1998，28，6： | 1 |
| 19 | Role of microfabric in matrix suction of residual soils显示文摘 | SUDHAKAR M RAOA K REVANASIDDAPPA | 2005 | Engineering Geology2005，80，： | 1 |
| 20 | Quantification of epistemic and aleatory uncertainties in level-1 probabilistic safety assessment studies 显示文摘 | RAOA K D KUSHWAHA H S VERMA A K | 2007 | Reliability Engineering and System Safety2007，92，7： | 1 |
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