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| 1 | Mitochondrial H2O2 generated from electron transport chain complex I stimulates muscle differentiation显示文摘Mitochondrial 反应的氧种类(mROS ) 被认为有害到房间。然而,他们的生理的角色一直不作为表明调停人是彻底地探索了。这里,我们调查了 mROS 是否从 mitochondrial 电子运输链(mETC ) 产生了复杂我刺激了肌肉区别。我们的结果证明 mROS 的数量被增加并且锰 superoxide dismutase (MnSOD ) 在肌肉区别期间经由 NF-B 激活被导致。指向线粒体的抗氧化剂(MitoQ 和 MitoTEMPOL ) 和指向线粒体的过氧化氢酶减少了没有影响 ATP 的数量的 mROS 数量和压制的肌肉区别。Mitochondrial 改变包括在线粒体的数字和尺寸的 mitochondrial 抄写因素 A 和增加的正式就职,并且功能的激活在肌肉区别期间被观察。特别地,增加了 mETC 建筑群的表示层次我子单元和建筑群的一项更高的活动我比另外的建筑群被观察。毒鱼藤素, mETC 建筑群的一个禁止者我,减少 mitochondrial NADH/NAD+ 比率和 mROS 层次在肌肉区别期间。mROS 铺平的我用小介入 RNA 和毒鱼藤素减少了的建筑群的抑制,压制的肌肉区别,和有伴随物的弄空的 ATP 层次在 glycolysis 增加。从这些结果,我们结束那复杂我导出 | Seonmin Lee Eunyoung Tak Jisun Lee MA Rashid Michael P Murphy Joohun Ha Sung Soo Kim | 2011 | Cell Research2011，21，5： | 4 |
| 2 | Inequalities in care in patients with acute myocardial infarction显示文摘Coronary heart disease is the single largest cause of death in developed countries. Guidelines exist for the management of acute myocardial infarction(AMI),yet despite these,significant inequalities exist in the care of these patients. The elderly,deprived socioeconomic groups,females and non-caucasians are the patient populations where practice tends to deviate more frequently from the evidence base. Elderly patients often had higher mortality rates after having an AMI compared to younger patients. They also tended to present with symptoms that were not entirely consistent with an AMI,thus partially contributing to the inequalities in care that is seen between younger and older patients. Furthermore the lack of guidelines in the elderly age group presenting with AMI can often make decision making challenging and may account for the discrepancies in care that are prevalent between younger and older patients. Other patients such as those from a lower socioeconomic group,i.e.,low income and less than high school education often had poorer health and reduced life expectancy compared to patients from a higher socioeconomic group after an AMI. Lower socioeconomic status was also seen to be contributing to racial and geographical variation is the care in AMI patients. Females with an AMI were treated less aggressively and had poorer outcomes when compared to males. However even when females were treated in the same way they continued to have higher in hospital mortality which suggests that gender may well account for differences in outcomes. The purpose of this review is to identify the inequalities in care for patients who present with an AMI and explore potential reasons for why these occur. Greater attention to the management and a better understanding of the root causes of these inequalities in care may help to reduce morbidity and mortality rates associated with AMI. | Shabnam Rashid Alexander Simms Phillip Batin John Kurian Chris P Gale | 2015 | World Journal of Cardiology2015，7，12： | 4 |
| 3 | Cardiovascular injuries associated with sternal fractures显示文摘 | Rashid MA Ortenwall P Wikstrom T | 2001 | Eur J Surg2001，167，4： | 1 |
| 4 | Blood pressure reduction and secondary prevention of stroke and other vascular events: a systematic review 显示文摘 | Rashid P Leonardi-Bee J Bath P | 2003 | Stroke2003，34，11： | 1 |
| 5 | Analysis and design of forced commutated cycloconverter structures with improved transfer characteristics显示文摘 | Ziogas P D Khan S I Rashid M H | 1986 | IEEE Trans on Industrial Electronics1986，33，3： | 1 |
| 6 | Blood pressure reduction and secondary prevention of stroke and other vascular events:a systemic review 显示文摘 | Rashid P Leonardi-Bee J Bath P | 2003 | Stroke2003，34，： | 1 |
| 7 | Plantlet formation from isolated protoplasts of Solanum melongena L显示文摘 | Saxena P K Gill R Rashid A | 1981 | Protoplasma1981，106，： | 1 |
| 8 | Some improved forced commutated cycloconverter structures显示文摘 | Ziogas P D Khan S I Rashid M H | 1985 | IEEE Trans on IAS1985，21，5： | 1 |
| 9 | Epidemiology of spinal cord injuries in the 2005 Pakistan earthquake 显示文摘 | RATHORE MF RASHID P BUTT AW | 2007 | Spinal Cord2007，45，10： | 1 |
| 10 | Thoraic vascular injuries:a major problem in trauma显示文摘 | Rashid MA Wikstrom T Ortenwall P | 2001 | Scand Cardiovas J2001，35，2： | 1 |
| 11 | Blood pressure reduction and secondary prevention of stroke and other vascular events显示文摘 | Rashid P Leonardi-Bee J Bath P | 2003 | Stroke2003，34，11： | 1 |
| 12 | Behavior of Aramid Fiber Reinforced Polymer Reinforced High Strength Concrete Beams under Bending 显示文摘 | Rashid M A Mansur M A Paramasivam P | 2000 | Journal of Composites for Construction2000，9，2： | 1 |
| 13 | Symptomatic urinary stone disease in pregnancy显示文摘 | Cheriachan D Arianayagam M Rashid P | | 0，，： | 1 |
| 14 | Synthesis,characterizationand biological evaluation of some thiourea derivatives bearingbenzothiazole moiety as potential antimicrobial and anticanceragents显示文摘 | Saeed S Rashid N Jones P G | 2010 | European Journal of Medical Chemistry2010，45，4： | 1 |
| 15 | Blood pressure reduction and secondary prevention of stroke and other vascular events : a systematic review 显示文摘 | Rashid P Leonardi-Bee J Bath P | 2003 | Stroke2003，34，： | 1 |
| 16 | Blood pressure reduction and secondary prevention of stroke and other vascular events:a systematic review显示文摘 | Rashid P Leonardi-Bee J Bath P | 2003 | Stroke2003，34，： | 1 |
| 17 | Bladder cancer current management显示文摘 | Arianayagam R Arianayagam M Rashid P | 2011 | Aust Faro Physician2011，40，： | 1 |
| 18 | Blood pressure reduction and secondary prevention of stroke and other vascular events:a systematic review显示文摘 | Rashid P Leonardi-Bee J Bath P | 2003 | Stroke2003，34，11： | 1 |
| 19 | Does D matter The role of vitamin D in hair disorders and hair follicle cycling显示文摘 | Amor KT Rashid RM Mirmirani P | 2010 | Dermatol Online J2010，16，2： | 1 |
| 20 | Blood pressure reduc- tion and secondary prevention of stroke and other vascu- lar events : a systematic review显示文摘 | Rashid P Leonardi-Bee J Bath P | 2003 | Stroke2003，34，11： | 1 |
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