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| 1 | Radioembolization for the treatment of unresectable hepatocellular carcinoma:A clinical review显示文摘Hepatocellular carcinoma(HCC)is the sixth most common cancer in the world.The majority of patients with HCC present with unresectable disease.These patients have historically had limited treatment options secondary to HCC demonstrating chemoresistance to the currently available systemic therapies.Additionally, normal liver parenchyma has shown intolerance to tumoricidal radiation doses,limiting the use of external beam radiation.Because of these limitations,novel percutaneous liver-directed therapies have emerged. The targeted infusion of radioactive microspheres (radioembolization)represents one such therapy. Radioembolization is a minimally invasive transcatheter therapy through which radioactive microspheres are infused into the hepatic arteries that supply tumor. Once infused,these microspheres traverse the hepatic vascular plexus and selectively implant within the tumor arterioles.Embedded within the arterioles, the 90Y impregnated microspheres emit high energy and low penetrating radiation doses selectively to the tumor.Radioembolization has recently shown promise for the treatment of patients with unresectable HCC. The objective of this review article is to highlight twocurrently available radioembolic devices(90Y,188Rh)and provide the reader with a recent review of the literature. | Saad M Ibrahim Robert J Lewandowski Kent T Sato Vanessa L Gates Laura Kulik Mary F Mulcahy Robert K Ryu Reed A Omary Riad Salem | 2008 | World Journal of Gastroenterology2008,14,11: | 14 |
| 2 | Diffusion-weighted magnetic resonance imaging to predict response of hepatocellular carcinoma to chemoembolization显示文摘AIM: To investigate whether intra-procedural diffusion- weighted magnetic resonance imaging can predict response of hepatocellular carcinoma (HCC) during trans- catheter arterial chemoembolization (TACE). METHODS: Sixteen patients (15 male), aged 59 ±11 years (range: 42-81 years) underwent a total of 21 separate treatments for unresectable HCC in a hybrid magnetic resonance/interventional radiology suite. Ana- tomical imaging and diffusion-weighted imaging (b = 0, 500 s/mm2) were performed on a 1.5-T unit. Tumor enhancement and apparent diffusion coefficient (ADC, mm2/s) values were assessed immediately before and at 1 and 3 mo after TACE. We calculated the percent change (PC) in ADC values at all time points. We compared follow-up ADC values to baseline values using a paired t test (α = 0.05). RESULTS: The intra-procedural sensitivity, specificity, and positive and negative predictive values (%) for detecting a complete or partial 1-mo tumor response using ADC PC thresholds of ±5%, ±10%, and ±15% were 77, 67, 91, and 40; 54, 67, 88, and 25; and 46, 100, 100, and 30, respectively. There was no clear predictive value for the 3-mo follow-up. Compared to baseline, the immediate post-procedure and 1-mo mean ADC values both increased; the latter obtaining statistical significance (1.48 ± 0.29 mm2/s vs 1.65 ± 0.35 × 10-3 mm2/s, P < 0.014). CONCLUSION: Intra-procedural ADC changes of > 15% predicted 1-mo anatomical HCC response with the greatest accuracy, and can provide valuable feedback at the time of TACE. | Johnathan C Chung Neel K Naik Robert J Lewandowski Mary F Mulcahy Laura M Kulik Kent T Sato Robert K Ryu Riad Salem Andrew C Larson Reed A Omary | 2010 | World Journal of Gastroenterology2010,16,25: | 13 |
| 3 | All-silicon carrier accumulation modulator based on a lateral metal-oxide-semiconductor capacitor显示文摘In silicon photonics, the carrier depletion scheme has been the most commonly used mechanism for demonstrating high-speed electro-optic modulation. However, in terms of phase modulation efficiency, carrieraccumulation-based devices potentially offer almost an order of magnitude improvement over those based on carrier depletion. Previously reported accumulation modulator designs only considered vertical metal-oxidesemiconductor(MOS) capacitors, which imposes serious restrictions on the design flexibility and integratability with other photonic components. In this work, for the first time to our knowledge, we report experimental demonstration of an all-silicon accumulation phase modulator based on a lateral MOS capacitor. Using a Mach–Zehnder interferometer modulator with a 500-μm-long phase shifter, we demonstrate high-speed modulation up to 25 Gbit∕s with a modulation efficiency(V_πL_π) of 1.53 V·cm. | KAPIL DEBNATH DAVID J.THOMSON WEIWEI ZHANG ALI Z.KHOKHAR CALLUM LITTLEJOHNS JAMES BYERS LORENZO MASTRONARDI MUHAMMAD K.HUSAIN KOUTA IBUKURO FREOERIC Y.GARDES GRAHAM T,REED SHINICHI SAITO | 2018 | Photonics Research2018,6,5: | 6 |
| 4 | The arterioportal fistula syndrome: Clinicopathologic features, diagnosis, and therapy显示文摘 | JN Vauthey RJ Tomczak T Helmberger P Gertsch C Forsmark J Caridi A Reed MR Langham GY Lauwers P Goffette J Lerut | 1997 | Gastroenterology1997,,4: | 2 |
| 5 | Molecular and immunological characterization of Mycobacterium tuberculosis CFP-10, an immunodiagnostic antigen missing in Mycobacterium boris BCG显示文摘 | Dillon DC Alderson MR Day CH Bement T Campos Neto A Skeiky YA Vedvick T Badaro R Reed SG Houghton R | 2000 | J Clin Microbiol2000,38,9: | 1 |
| 6 | Informal logic dialogue games in human-computer dialogue显示文摘 | Yuan T Moore D Reed C | 2009 | Knowledge Engineering Review2009,26,3: | 1 |
| 7 | The effect of apoliporotein Ee4 in the relationships of smoking and drinking to cognitive function显示文摘 | Carmelli D Swan GE Reed T | 1999 | Neuroepidemiology1999,18,: | 1 |
| 8 | Tumor suppressor p53 is a direct transcriptional activator of the human Bax gene 显示文摘 | Miyashita T Reed J C | 1995 | Cell1995,80,2: | 1 |
| 9 | Development of a global land cover characteristics database and IGBP DISCover from 1km AVHRR data 显示文摘 | Loveland T R Reed B C Brown J F | 2000 | International Journal of Remot Sensing2000,21,67: | 1 |
| 10 | Bcl-2 oncoprotein blocks chemotherapy-induced apoptosis in ahuman leukemia cell line显示文摘 | Miyashita T Reed JC | 1993 | Blood1993,81,: | 1 |
| 11 | Tumor suppressor p53 is a direct transcriptional activator of the human bax gene显示文摘 | Miyashita T Reed JC | 1995 | Cell1995,80,12: | 1 |
| 12 | Systolic multipliers for finite fields GF(2m)显示文摘 | YEH C S REED I S TRUONG T K | | 0,,04: | 1 |
| 13 | The FLIP-side of Fas signaling显示文摘 | Hyer ML Samuel T Reed JC | 2006 | Clin Cancer Res2006,12,20: | 1 |
| 14 | Bcl-2 oncoprotein blocks chemotherapy-induced apoptosis in a human leukemia cell line显示文摘 | Miyashita T Reed JC | 1993 | Blood1993,81,1: | 1 |
| 15 | Development of a global land cover characteristics database and IGBP DISCover from 1 km AVHRR data显示文摘 | Loveland T R Reed B C Brown J F | 2000 | International Journal of Remote Sensing( in review)2000,21,7: | 1 |
| 16 | Large Area GaN Substrates显示文摘 | Kryliouk O Reed M Dann T Anderson T Chai B | 1999 | Materials Science and Engineering B1999,59,13: | 1 |
| 17 | Regulation of p26- bcl -2 protein levels in human peripheral blood lymphocytes 显示文摘 | Reed JC Miyashita T Cuddy M | 1992 | Lab Invest1992,67,4: | 1 |
| 18 | Decoding the(73, 37, 13 ) quadratic residue code 显示文摘 | CHEN X REED I S TRUONG T K | 1994 | Proceeding of the IEE1994,141,: | 1 |
| 19 | Enhanced wood fuels via torrefaction显示文摘 | LIPINSKY E S ARCATE J R Reed T B | 2002 | Fuel Chemistry Division Preprints2002,47,1: | 1 |
| 20 | TWACS, A New Viable Two Way Automatic Communication System for Distribution Networks, Part I: Outbound Communication 显示文摘 | Mak Sioe T Reed Don L | 1982 | IEEE Transaction on Power Apparatus and Systems1982,101,8: | 1 |