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| 1 | Alpha-fetoprotein expression is a potential prognostic marker in hepatocellular carcinoma显示文摘AIM: To characterize the alpha-fetoprotein (AFP) positive and negative hepatocellular carcinoma (HCC) samples.METHODS: Thirty-seven paraffin-embedded human HCC samples were analyzed by immunohistochemistry for the following antigens: AFP, β-catenin, p53, CD44, MSH-2,MLH-1, and HNF-4. The tumors were divided into two groups based on the AFP expression. The immunophenotypic data and important clinical parameters were studied between the two groups.RESULTS: Twenty-one of the thirty-seven examined HCCs were AFP positive. Seven with nuclear p53 staining were AFP positive, while seven tumors with nuclear β-catenin staining were AFP negative. CD44 staining and high histological tumor grade were more frequent among the AFP-positive HCCs. The other immunophenotypical and dinical parameters did not show statistically significant difference in their distribution between the AFP positive and negative samples.CONCLUSION: AFP expression in HCC correlates with unfavorable prognostic factors, while nuclear β-catenin positivity is more common among the AFP-negative liver tumors. This observation supports the microarray data onin vivo human tumors. | Dénes Grg János Regly-Mérei Sándor Paku László Kopper Péter Nagy | 2005 | World Journal of Gastroenterology2005，11，32： | 6 |
| 2 | Acute gouty synovitis associated with 'urate milk' 显示文摘 | FAM A G REIS M D SZALAI J P | 1997 | J Rheumatol1997，24，12： | 1 |
| 3 | Advances in enhanced biological phosphorus removal:from micro to macro scale显示文摘 | Oehmen A Lemos P C Carvalho G Yuan Z Kelley J Blackall L L Reis M A M | 2007 | Water Research2007，41，11： | 1 |
| 4 | Reducing virulence of the human pathogen Burkholderia by altering the substrate specificity of the quorum-quenching acylase PvdQ显示文摘 | Koch G Nadal-Jimenez P Reis CR | 2014 | National Academy of Sciences2014，111，4： | 1 |
| 5 | Purification and characterization of Aspergillus terreus a-galactosidases and their use for hydrolysis of soymilk oligosaccharides显示文摘 | FERREIRA J G REIS A P GUIMARAES V M | 2011 | Applied Biochemistry and Biotechnology2011，164，7： | 1 |
| 6 | Some aspects of sulfur containing amino acids on the growth and composition of wool显示文摘 | Reis P J Schinckel P G | 1963 | Austr J Biol Sci1963，16，： | 1 |
| 7 | Nitrogen utilization and wool production by sheep显示文摘 | Reis P J Schinekel P G | 1961 | Austr J Agric Res1961，12，： | 1 |
| 8 | Cutting performance of time-modulated chemical vapour deposited diamond coated tool inserts during machining graphite显示文摘 | Cabral G Reis P Polini R | 2006 | Diamond and Related Materials2006，15，10： | 1 |
| 9 | Calculating Growth Parameters of Genidens Barbus ( Siluriformes, Ariidae) Using Length Composition and Age Data显示文摘 | Velasco G Reis E G Vieira J P | 2007 | Journal of Applied Ichthyology2007，23，： | 1 |
| 10 | Some aspects of sulfur containing amino acids on the growth and composition of wool 显示文摘 | Reis P J Schinckel P G | 1963 | Austr J Biolog Sci1963，16，： | 1 |
| 11 | Denitrifying phosphorus removal: Linking the process performancewith the microbial community structure 显示文摘 | Carvalho G Lemos P C Oehmen A Reis M | 2007 | Water Research2007，41，19： | 1 |
| 12 | Impact of surface roughness of diamond coatings on the cutting performance when drymachining of graphite 显示文摘 | CABRAL G REIS P TITUS E MADALENO J C DAVIM J P GRACIO J AHMED W JACKSON M J | 2008 | International Journal of Manufacturing Technology and Management2008，15，： | 1 |
| 13 | Integrated coastal zone management in the Patos Lagoon estuary:perspectives in context of developing country显示文摘 | TAGLIANI P R A LANDAZURI H REIS E G | 2003 | Ocean & Coastal Management2003，46，： | 1 |
| 14 | Influence of cold tem- perature on bulb dormancy break and vernalization of four lily va- rieties 显示文摘 | Abreu R M Barbosa J G Reis F P | 2003 | Revista Geres Universidada Fedural Deviosa Vi- cose Brazi2003，50，288： | 1 |
| 15 | Natural-origin polymers as carriers and scaffolds for biomolecules and cell delivery in tissue engineering applications显示文摘 | Malafaya P B Silva G A Reis R L | | 0，，4： | 1 |
| 16 | Effects of the infusion of amino acids into the abomasums of sheep with emphasis on the relative value of methionine, Cysteine and homo-Cysteine for wool growth 显示文摘 | Reis P J Tunks D A Munro S G | 1990 | J Agric Sci Cambridge1990，114，： | 1 |
| 17 | Adsorption of paraquat from aqueous medium by amberlite XAD-2 and XAD-4 resins using dodecylsulfate ascounter ion显示文摘 | LEITE M P DOS REIS L G T ROBAINA N F | 2013 | Chemical Engineering Journal2013，，： | 1 |
| 18 | Molecular classification of oral cancer by cDNA microarrays identifies overexpressed genes correlated with nodal metastasis显示文摘 | WARNER G C REIS P P JURISICA I | 2004 | Int J Cancer2004，110，： | 1 |
| 19 | Hydroxychloroquine in pediatric idiopathic pulmonary hemosiderosis-a case report 显示文摘 | ALMEIDA M P REIS G GUEDES M | 2006 | Rev Port Pneumol2006，12，1： | 1 |
| 20 | Cutting Perform- ance of Time-modulated Chemical Vapour Deposi- ted Diamond Coated Tool Inserts during Machining Graphite 显示文摘 | Cabral G Reis P Polini R | 2006 | Diamond and Related Materials2006，15，10： | 1 |
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