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| 1 | Concordance of non-invasive mechanical and serum tests for liver fibrosis evaluation in chronic hepatitis C显示文摘AIM To determine the sensitivity and specificity of liver stiffness measurement(LSM) and serum markers(SM) for liver fibrosis evaluation in chronic hepatitis C.METHODS Between 2012 and 2014,81 consecutive hepatitis C virus(HCV) patients had METAVIR score from liver biopsy compared with concurrent results from LSM [transient elastography(TE) [FibroS can~/ARFI technology(Virtual Touch~)] and SM [FIB-4/aspartate aminotransferase-toplatelet ratio index(APRI)].The diagnostic performance of these tests was assessed using receiver operating characteristic curves.The optimal cut-off levels of each test were chosen to define fibrosis stages F ≥ 2,F ≥ 3 and F = 4.The Kappa index set the concordance analysis.RESULTS Fifty point six percent were female and the median age was 51 years(30-78).Fifty-six patients(70%) weretreatment-na?ve.The optimal cut-off values for predicting F ≥ 2 stage fibrosis assessed by TE were 6.6 kP a,for acoustic radiation force impulse(ARFI) 1.22 m/s,for APRI 0.75 and for FIB-4 1.47.For F ≥ 3 TE was 8.9 kP a,ARFI was 1.48 m/s,APRI was 0.75,and FIB-4 was 2.For F = 4,TE was 12.2 kP a,ARFI was 1.77 m/s,APRI was 1.46,and FIB-4 was 3.91.The APRI could not distinguish between F2 and F3,P = 0.92.The negative predictive value for F = 4 for TE and ARFI was 100%.Kappa index values for F ≥ 3 METAVIR score for TE,ARFI and FIB-4 were 0.687,0.606 and 0.654,respectively.This demonstrates strong concordance between all three screening methods,and moderate to strong concordance between them and APRI(Kappa index = 0.507).CONCLUSION Given the costs and accessibility of LSM methods,and the similarity with the outcomes of SM,we suggest that FIB-4 as well as TE and ARFI may be useful indicators of the degree of liver fibrosis.This is of particular importance to developing countries. | Denise C Paranaguá-Vezozzo Adriana Andrade Daniel F C Mazo Vinicius Nunes Ana L Guedes Taisa G Ragazzo Renata Moutinho Lucas S Nacif Suzane K Ono Venancio A F Alves Flair J Carrilho | 2017 | World Journal of Hepatology2017，9，8： | 7 |
| 2 | Optimization of room-and-pillar dimensions using automated numerical models显示文摘This paper presents an optimization methodology for the geometric configuration of a room–and–pillar mining project,considering safety and operational restrictions while maximizing ore recovery.An underground manganese mine was chosen as a case study to investigate the capabilities of the presented methodology.A software package(OPTIMINE)was implemented to address the computational demand in an automated manner.Three–dimensional finite difference analyses were performed in FLAC3D and used as implicit functions to consider safety in terms of the factor of safety and room convergence.The obtained results showed that recovery could be increased from 44%to more than 80%in a safe manner. | Gian Franco Napa-García Tais Renata Camara Vidal Félix Navarro Torres | 2019 | International Journal of Mining Science and Technology2019，29，5： | 2 |
| 3 | Carotid Artery Stenosis:Intraindividual Correlations of 3D Time-of flight MR Angiography, Contrast-enhanced MR Angiography, Conventional DSA, and Rotational Angiography for Detection and Grading显示文摘 | Anzalone N Scomazzoni F Renata C | 2005 | Radiology2005，236，1： | 1 |
| 4 | Empirical modeling of butyl acrylate/vinyl acetate/acrylic acid emulsion-based pressure-sensitive adhesives显示文摘 | JOVANOVIC RENATA MCKENNA TIMOTHY F DUBE MARC A | 2004 | Macromolecular Materials and Engineering2004，289，5： | 1 |
| 5 | Oral cancer after prolonged immunosuppression for multiorgan chronic graft- versus-host disease显示文摘 | Renata L Karine F Vaneuza M et a | 2014 | Reista Bransileira de Hematologia e Hemoterapia2014，36，1： | 1 |
| 6 | Encapsulationefficiency and oxidative stability of flaxseed oil microencapsulatedby spray drying using different combinations of wall materials显示文摘 | Helena C F Carneiro Renata V Tonon | 2013 | Journal of Food Engineering2013，115，4： | 1 |
| 7 | Influence of emulsion composition and inlet air temperature on the microencapsulation of flaxseed oil by spray drying显示文摘 | Renata V Tonon Carlos R F Grosso Miriam D Hubinger | | 0，，01： | 1 |
| 8 | Persistence of high CD40 and CD40L expression after restorative proctocolectomy for ulcerative colitis显示文摘AIM: To focus on the role of CD40 and CD40L in their pathogenesis.METHODS: We analyzed by immunohistochemistry the CD40 and CD40L expression in the pouch mucosa of 28 patients who had undergone RPC for UC, in the terminal ileum of 6 patients with UC and 11 healthy subjects. We also examined by flow cytometry the expression of CD40 by B lymphocytes and monocytes in the peripheral blood of 20 pouch patients, 15 UC patients and 11 healthy controls.RESULTS: Ileal pouch mucosa leukocytes presented a significantly higher expression of CD40 and CD40L as compared to controls. This alteration correlated with pouchitis, but was also present in the healthy pouch and in the terminal ileum of UC patients. CD40 expression of peripheral B lymphocytes was significantly higher in patients with UC and pouch, respect to controls. Increased CD40 levels in blood B cells of pouch patients correlatedwith the presence of spondyloarthropathy, but not with pouchitis, or inflammatory indices.CONCLUSION: High CD40 expression in the ileal pouch mucosa could be implied in the pathogenesis of pouchitis following proctocolectomy for UC, whereas its increased levels on peripheral blood B lymphocytes are associated with the presence of extraintestinal manifestations. | Lino Polese Imerio Angriman Giuseppe De Franchis Attilio Cecchetto Giacomo C.Sturniolo Renata D'Incà Marco Scarpa Cesare Ruffolo Lorenzo Norberto Mauro Frego Davide F D'Amico | 2005 | World Journal of Gastroenterology2005，11，34： | 1 |
| 9 | Study of coating distribution onto metallic hollow particles 显示文摘 | Renata Ornakova Andrej Orinak Heinrich F Arlinghaus Sebastian Hellweg Miriam Kupkova Margita Kabatova | 2006 | Applied Surface Science2006，252，： | 1 |
| 10 | Long-term high-fat diet-induced obesity decreases the cardiac leptin receptor without apparent lipotoxicity显示文摘 | André F. Nascimento Renata A.M. Luvizotto André S. Leopoldo Ana P. Lima-Leopoldo Fábio R. Seiva Luís A. Justulin Maeli Dal Pai Silva Katashi Okoshi Xiang-Dong Wang Antonio C. Cicogna | 2011 | Life Sciences2011，，23： | 1 |
| 11 | Influence of emulsion composition and inlet air temperature on the microencapsulation of flaxseed oil by spray drying 显示文摘 | Renata V Tonon Carlos R F Grosso Miriam D Hubinger | 2011 | Food Research International2011，，1： | 1 |
| 12 | Tourism and older residents in a sunbell resort 显示文摘 | RENATA T BILL F | 2000 | Annals of tourism research2000，27，1： | 1 |
| 13 | Osmotic dehydra-tion of tomato in ternary solutions:Influence of process vari-ables on mass transfer kinetics and an evaluation of the re-tention of carotenoids显示文摘 | Renata V T Alessandra F B Miriam D H | 2007 | Journal of Food Engineering2007，，82： | 1 |
| 14 | Colon carcinoma in patients undergoing liver transplantation显示文摘 | Renata Fabia Marlon F Levy Giuliano Testa Samuel Obiekwe Robert M Goldstein Bo S Husberg Thomas A Gonwa Goran B Klintmalm | 1998 | The American Journal of Surgery1998，，3： | 1 |
| 15 | Virulence factors genes of Staphylococcus spp. isolated from caprine subclinical mastitis显示文摘 | Sandra Renata Sampaio Salaberry André Becker Sim?es Saidenberg Eveline Zuniga Priscilla Anne Melville Franklin Ger?nimo Bispo Santos Ednaldo Carvalho Guimar?es Fábio Gregori Nilson Roberti Benites | 2015 | Microbial Pathogenesis2015，，： | 1 |
| 16 | Tourism and older residents in a sunbelt resort 显示文摘 | Renata T Bill F | 2000 | Annals of Tourism Research2000，27，： | 1 |
| 17 | Tourism and Older Residents in a Sunbell Resort 显示文摘 | Renata T Bill F | 2000 | An- nals of Tourism Research2000，27，1： | 1 |
| 18 | Empirical Modeling of Butyl Acrylate/Vinyl Acetate/Acrylic Acid Emulsion-Based Pressure-Sensitive Adhesives 显示文摘 | RENATA J TIMOTHY F M MARC A D | 2004 | Macromolecular materials and engineering2004，289，： | 1 |
| 19 | Fungi that produce my-cotoxins: conditions and occurrence 显示文摘 | Antonio F M Renata R C Myma S | 1998 | Mycopathologia1998，65，7： | 1 |
| 20 | Comparison of three methods of nutritional assessment in liver cirrhosis: subjective global assessment, traditional nutritional parameters, and body composition analysis显示文摘 | Fátima A.F. Figueiredo Renata M. Perez Márcia M. Freitas Mário Kondo | 2006 | Journal of Gastroenterology2006，，5： | 1 |
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