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33篇 您的检索式:作者名="Reno P"
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1银屑病皮损免疫病理表型特征及其体外维持显示文摘目的 研究银屑病皮损免疫表型及其体外维持。方法 检测代表银屑病病理特征的蛋白分子 ,并观察培养后这些分子的变化。结果 银屑病皮损中角蛋白 16、17、转谷酰酶I、ICAM 1、HLA DR、β1整合素及OKM 5增强表达 ,培养48h后和培养前基本相同。结论 上述蛋白分子的共同表达构成了银屑病皮损的免疫表型 ,这种表型在跨膜皮肤器官模型中 48h培养可得到良好的维持。刘玮 赵庆利 张新华 Reno Debets Errol P Prens 2000中国皮肤性病学杂志2000,14,2:4
2白介素-1β诱导正常人皮肤表达银屑病免疫病理表型显示文摘目的对白介素 -1β(IL 1β)在启动银屑病免疫病理表型中的作用进行研究。方法取健康人正常皮肤在跨膜(transwell)皮肤器官培养模型中进行培养 ,观察在IL 1β或白介素 -1受体拮抗剂(IL 1ra)等细胞因子刺激下 ,培养皮肤表达银屑病免疫病理特征标记物的情况。结果在IL 1β 刺激下 ,正常人皮肤表达了一系列银屑病相关的蛋白分子 ,即角蛋白16、17在表皮棘细胞层强阳性 ;Ⅰ型转谷酰胺酶从表皮颗粒层到棘细胞层过度表达 ;ICAM 1、HLA DR以及β1整合素在表皮基底细胞层和棘细胞层诱导表达或增强表达。培养基中加入IL 1ra可使上述标记物的表达受到显著抑制。培养基中加入抗IL 1β抗体可完全阻断IL 1β的上述诱导作用。结论在培养条件下IL 1β可诱导正常人皮肤表达银屑病的免疫病理表型 ,提示IL 1系统参与了银屑病的皮损形成。刘玮 赵庆利 Reno Debets 蔡瑞康 Errol P Prens 1999中华皮肤科杂志1999,32,2:2
3Polypeptides p40, pOM2, and pAngR are required for iron uptake and for virulence of the marine fish pathogen Vibrio anguillarum 显示文摘Singer J T Schmidt K A Reno P W 1991Bacteriology1991,173,3:1
4Postmortem stability of total RNA isolated from rabbit ligament,tendon and cartilage显示文摘MARCHUK L SCIORE P RENO C 1998Biochim Biophys Acta1998,1379,2:1
5Paraffin isomeriza- tion innovations显示文摘Kuchar P J Bricker J C Reno M E 1993Fuel Processing Technology1993,35,:1
6Prevalence and geographic range of Nadelspora canceri (Microspora) in Dungeness crab Cancer magister 显示文摘RICHARD K C RENO P W OLSON R E 1996Disease of Aquatic Organisms1996,,24:1
7Humanspecific loss of regulatory DNA and the evolution of human- specific traits 显示文摘MCLEAN C Y RENO P L POLLEN A A 2011Nature2011,471,:1
8Joint immobilization reduces the expression of sensory neuropeptide receptors and impairs healing after tendon rup ture in a rat model显示文摘Bring DK Reno C Renstrom P 0,,02:1
9Polypeptides p40, pOM2, and pAngR are required for iron uptake and for virolence of the marine fish pathogen V~brio anguillarum 775 显示文摘Singer J T Schmidt K A Reno P W 1991J Baeteriol1991,173,:1
10Postmortem stability of total RNA isolated from rabbit ligament,tendon and cartilage显示文摘Marchuk L Sciore P Reno C 1998Biochim Biophys Acta1998,1379,2:1
11Rapidisolation of total RNA from small samples of hypocellular,dense connective tissues显示文摘Reno C Marchuk L Sciore P 1997Biotechniques1997,22,6:1
12Solitary fibrous tumor of the pleura : suigieal treatment显示文摘Reno O Fillosso P L Papalia E 2001Eur J Cardiotho racSurg2001,19,:1
13Postmortem stability of total RNA isolated from rabbit ligament,tendon and cartilage显示文摘Marchuk L Sciore P Reno C 1998Biochim BiophysActa1998,1379,2:1
14Transcriptome response of the Pacific oyster (Crassostrea gigas ) to infection with Vibrio tubiashii using cDNA AFLP differential display 显示文摘TARISN LANG R P RENO P W 2009Immunogentics Molecular Genetics and Functional Genornics2009,40,5:1
15Characteristics of inhibition of infectious pancreatic necrosis virus(IPNV)by normal rainbow trout Oncorhynchus mykiss serum显示文摘Park K C Reno P W 2005Diseases of Aquatic Organisms2005,63,1:1
16Solitary fibrous tumour of the pleura:suigical treatment显示文摘Reno O Fillosso P L Papalia E 0,,02:1
17Monoclonal antibodies to infectious pancreatic necrosis virus: analysis of viral epitopes and comparison of different isolates显示文摘Caswell Reno P Nicholson B 1986Journal of General Virology1986,67,10:1
18Paraffin isomerization innovations显示文摘Kuchar P J Bricker J C Reno M E 1993Fuel Processing Technology1993,35,:1
19Antigenic analysis of Asian birnavirus isolates using monoclonal antibodies 显示文摘Lipipun V Caswell-Reno P Hsu Y L Wu J L Tung M C Reno P W Wattanavijarn W Nicholson B L 1989Fish Pathol1989,24,:1
20Postmortem stabil- ity of total RNA isolated from rabbit ligament, tendon and cartilage显示文摘Marchuk L Sciore P Reno C 1998Biochim Biophys Acta1998,1379,2:1
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