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| 1 | Retrograde-viewing device improves adenoma detection rate in colonoscopies for surveillance and diagnostic workup显示文摘AIM:To determine which patients might benefit most from retrograde viewing during colonoscopy through subset analysis of randomized,controlled trial data.METHODS:The Third Eye Retroscope Randomized Clinical Evaluation(TERRACE) was a randomized,controlled,multicenter trial designed to evaluate the efficacy of a retrograde-viewing auxiliary imaging device that is used during colonoscopy to provide a second video image which allows viewing of areas on the proximal aspect of haustral folds and flexures that are difficult to see with the colonoscope's forward view.We performed a post-hoc analysis of the TERRACE data to determine whether certain subsets of the patient population would gain more benefit than others from use of the device.Subjects were patients scheduled for colonoscopy for screening,surveillance or diagnostic workup,and each underwent same-day tandem examinations with standard colonoscopy(SC) and Third Eye colonoscopy(TEC),randomized to SC followed by TEC or vice versa.RESULTS:Indication for colonoscopy was screening in 176/345 subjects(51.0%),surveillance after previous polypectomy in 87(25.2%) and diagnostic workup in 82(23.8%).In 4 subjects no indication was specified.Previously reported overall results had shown a net additional adenoma detection rate(ADR) with TEC of 23.2% compared to SC.Relative risk(RR) of missing adenomas with SC vs TEC as the initial procedure was 1.92(P = 0.029).Post-hoc subset analysis shows additional ADRs for TEC compared to SC were 4.4% for screening,35.7% for surveillance,55.4% for diagnostic and 40.7% for surveillance and diagnostic combined.The RR of missing adenomas with SC vs TEC was 1.11(P = 0.815) for screening,3.15(P = 0.014) for surveillance,8.64(P = 0.039) for diagnostic and 3.34(P = 0.003) for surveillance and diagnostic combined.Although a multivariate Poisson regression suggested gender as a possibly significant factor,subset analysis showed that the difference between genders was not statistically significant.Age,bowel prep quality and withdrawal time did not significantly affect the RR of missing adenomas with SC vs TEC.Mean sizes of adenomas detected with TEC and SC were similar at 0.59 cm and 0.56 cm,respectively(P = NS).CONCLUSION:TEC allows detection of significantly more adenomas compared to SC in patients undergoing surveillance or diagnostic workup,but not in screening patients(ClinicalTrials.gov Identifier:NCT01044732). | Peter D Siersema Amit Rastogi Anke M Leufkens Paul A Akerman Kassem Azzouzi Richard I Rothstein Frank P Vleggaar Alessandro Repici Giacomo Rando Patrick I Okolo Olivier Dewit Ana Ignjatovic Elizabeth Odstrcil James East Pierre H Deprez Brian P Saunders Anthony N Kalloo Bradley Creel Vikas Singh Anne Marie Lennon Daniel C DeMarco | 2012 | World Journal of Gastroenterology2012，18，26： | 6 |
| 2 | Wallflex colonic stent placement for management of malignant colonic obstruction:a prospective study at two centers显示文摘 | Repici A De CG Luigiano C | 2008 | Gastrointest Endosc2008，67，： | 1 |
| 3 | WallFlex colonic stent placement for management of malignant colonic obstruction:a prospective study at two centers显示文摘 | Repici A De Caro G Luigiano C | 2008 | Gastrointest Endosc2008，67，1： | 1 |
| 4 | Covered metal stents for management of inoperable malignant colorectal strictres 显示文摘 | REPICI A REGGIO D DE ANGELIS C | 2000 | Gastrointest Endosc2000，52，： | 1 |
| 5 | WallFlex colonic stent placement for management of malignant colonic obstruction:a prospective study at two centers显示文摘 | Repici A De Caro G Luigiano C | 2008 | Gastrointest Endosc2008，67，1： | 1 |
| 6 | Endoscopic sub-mucosal dissection of gastric neo-plastic lesion in patients with liver eirrho- sis : a systematic review显示文摘 | Repici A Pagaw N Massan C | 2012 | J Gastrointestinal Liver Dis2012，21，3： | 1 |
| 7 | Colonic polyps : are we ready to resect and discard? 显示文摘 | Hassan C Repici A Zullo A | 2013 | Gastrointest Endosc Clin N Am2013，23，3： | 1 |
| 8 | A randomized prospective comparison of self-expandable plastic stents and partially covered self-expandable metal stents in the palliation of malignant esophageal dysphagia显示文摘 | Conio M Repici A Battaglia G | 2007 | Am J Gastroenterol2007，102，11： | 1 |
| 9 | Early arid late out- come of patients with obstructing colorectal cancer treat- ed by stenting and elective surgery:a comparison with e- mergency surgery and patients operated without obstruc- tive symptoms 显示文摘 | Repici A Conio M Caronna S | 2004 | Gastrointest Endosc2004，59，5： | 1 |
| 10 | Use of a colonoscope for distal duodenal stent placement in patients with malignant obstruction显示文摘 | Jeurnink SM Repici A Luiqiano C | 2009 | Surg Endosc2009，23，： | 1 |
| 11 | WallFlex colonic stent placement for management of malignant colonic ob- struction:a prospective study at two centers显示文摘 | Repici A De Caro G Luigiano C | 2008 | Gastroin- test Endosc2008，67，1： | 1 |
| 12 | Insulated-tip knife endoscopic mucosal resection of large eolorectal polyps un- suitable for standard polypectomy 显示文摘 | Repici A Conio M De Angelis C | 2007 | Am J Gastroenterol2007，102，8： | 1 |
| 13 | Success and safety of endoscopic treatments for concomitant biliary and duodenal malignant stenosis: A review of the literature显示文摘Synchronous biliary and duodenal malignant obstruction is a challenging endoscopic scenario in patients affected with ampullary, peri-ampullary, and pancreatic head neoplasia. Surgical bypass is no longer the gold-standard therapy for these patients, as simultaneous endoscopic biliary and duodenal stenting is currently a feasible and widely used technique, with a high technical success in expert hands. In recent years, endoscopic ultrasonography(EUS) has evolved from a diagnostic to a therapeutic procedure, and is now increasingly used to guide biliary drainage, especially in cases of failed endoscopic retrograde cholangiopancreatography(ERCP). The advent of lumen-apposing metal stents(LAMS) has expanded EUS therapeutic options, and changed the management of synchronous bilioduodenal stenosis. The most recent literature regarding endoscopic treatments for synchronous biliary and duodenal malignant stenosis has been reviewed to determine the best endoscopic approach, also considering the advent of an interventional EUS approach using LAMS. | Benedetto Mangiavillano Mouen A Khashab Ilaria Tarantino Silvia Carrara Rossella Semeraro Francesco Auriemma Mario Bianchetti Leonardo Henry Eusebi Chen Yen-I Luca De Luca Mario Traina Alessandro Repici | 2019 | World Journal of Gastrointestinal Surgery2019，11，2： | 1 |
| 14 | From EMR to ESD:A new challenge from Japanese endoucopists显示文摘 | Repici A | 2007 | Digestive and Liver Disease2007，39，6： | 1 |
| 15 | The natural history of gastroin- testinal subepithelial tumors arising from muscularis propria: an endo- scopic ultrasound survey 显示文摘 | Bruno M Carucci P Repici A | 2009 | J Clin Gastroenterol2009，43，9： | 1 |
| 16 | Endoscopic treatment of malignant gastric and duodenal strictures: a prospective, multi- center study显示文摘 | Tringali A Didden P Repici A eta/ | 2014 | Gastrointest Endose2014，79，1： | 1 |
| 17 | Efficacy and safety of biodegradable stents for refractory benign esophageal strictures: the BEST (Biodegradable Esophageal Stent) study显示文摘 | Repici A Vleggaar FP Hassan C | 2010 | Gastrointest Endosc2010，72，： | 1 |
| 18 | Covered metal stents for management of inoperable malignant calorectal strictures 显示文摘 | REPICI A REGGIO D DE ANGELIS C | 2000 | Gastrointest Endosc2000，52，6： | 1 |
| 19 | New design esopha- geal stents for the palliation of dysphagia from esophageal or gas- tric cardia cancer: a randomized trial显示文摘 | Verschuur E M Repici A Kuipers E J | 2008 | Am J Gastroenterol2008，103，30： | 1 |
| 20 | Insulatedtip knifeen- doscopic mucosal resection of large eolorectal polyps un- suitable for standard polypectomy显示文摘 | Repici A Conio M De Angelis C | 2007 | Am J Gastroenterol2007，102，8： | 1 |
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