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| 1 | Radioembolization for the treatment of unresectable hepatocellular carcinoma:A clinical review显示文摘Hepatocellular carcinoma(HCC)is the sixth most common cancer in the world.The majority of patients with HCC present with unresectable disease.These patients have historically had limited treatment options secondary to HCC demonstrating chemoresistance to the currently available systemic therapies.Additionally, normal liver parenchyma has shown intolerance to tumoricidal radiation doses,limiting the use of external beam radiation.Because of these limitations,novel percutaneous liver-directed therapies have emerged. The targeted infusion of radioactive microspheres (radioembolization)represents one such therapy. Radioembolization is a minimally invasive transcatheter therapy through which radioactive microspheres are infused into the hepatic arteries that supply tumor. Once infused,these microspheres traverse the hepatic vascular plexus and selectively implant within the tumor arterioles.Embedded within the arterioles, the 90Y impregnated microspheres emit high energy and low penetrating radiation doses selectively to the tumor.Radioembolization has recently shown promise for the treatment of patients with unresectable HCC. The objective of this review article is to highlight twocurrently available radioembolic devices(90Y,188Rh)and provide the reader with a recent review of the literature. | Saad M Ibrahim Robert J Lewandowski Kent T Sato Vanessa L Gates Laura Kulik Mary F Mulcahy Robert K Ryu Reed A Omary Riad Salem | 2008 | World Journal of Gastroenterology2008，14，11： | 14 |
| 2 | Diffusion-weighted magnetic resonance imaging to predict response of hepatocellular carcinoma to chemoembolization显示文摘AIM: To investigate whether intra-procedural diffusion- weighted magnetic resonance imaging can predict response of hepatocellular carcinoma (HCC) during trans- catheter arterial chemoembolization (TACE). METHODS: Sixteen patients (15 male), aged 59 ±11 years (range: 42-81 years) underwent a total of 21 separate treatments for unresectable HCC in a hybrid magnetic resonance/interventional radiology suite. Ana- tomical imaging and diffusion-weighted imaging (b = 0, 500 s/mm2) were performed on a 1.5-T unit. Tumor enhancement and apparent diffusion coefficient (ADC, mm2/s) values were assessed immediately before and at 1 and 3 mo after TACE. We calculated the percent change (PC) in ADC values at all time points. We compared follow-up ADC values to baseline values using a paired t test (α = 0.05). RESULTS: The intra-procedural sensitivity, specificity, and positive and negative predictive values (%) for detecting a complete or partial 1-mo tumor response using ADC PC thresholds of ±5%, ±10%, and ±15% were 77, 67, 91, and 40; 54, 67, 88, and 25; and 46, 100, 100, and 30, respectively. There was no clear predictive value for the 3-mo follow-up. Compared to baseline, the immediate post-procedure and 1-mo mean ADC values both increased; the latter obtaining statistical significance (1.48 ± 0.29 mm2/s vs 1.65 ± 0.35 × 10-3 mm2/s, P < 0.014). CONCLUSION: Intra-procedural ADC changes of > 15% predicted 1-mo anatomical HCC response with the greatest accuracy, and can provide valuable feedback at the time of TACE. | Johnathan C Chung Neel K Naik Robert J Lewandowski Mary F Mulcahy Laura M Kulik Kent T Sato Robert K Ryu Riad Salem Andrew C Larson Reed A Omary | 2010 | World Journal of Gastroenterology2010，16，25： | 13 |
| 3 | Study and performaned evaluation of two iterative frequency-domain deconvolution techniques显示文摘 | B Parruck S M Riad | 1994 | IEEE Trans1994，43，2： | 2 |
| 4 | Finite Element Model of Smart Beams with Distributed'Piezoelectric Actuators显示文摘 | Bendary I M Elshafei M A Riad A M | 2010 | Journal of Intelligent Material Systems and Structures2010，，3： | 1 |
| 5 | Aggressive fibromatosis of the head and neck显示文摘 | Abdelkader M Riad M Williams A | 2001 | J Laryngol Otol2001，115，10： | 1 |
| 6 | Toll -like receptor-4 modu- lates survival by induction of left ventricular remodeling after myo- cardial infarction in mice 显示文摘 | Riad A Jager S Sobirey M | 2008 | J Immunol2008，180，10： | 1 |
| 7 | Detection of chlorides in concrete using low radio frequencies显示文摘 | Al-Qadi I L Haddad R H Riad S M | 1997 | Journal of Materials in Civil Engineering1997，9，1： | 1 |
| 8 | Modeling of the HP-1430A Feedthrough Wide-Band (28-ps) Sampling Head显示文摘 | RIAD S M | 1982 | IEEE Transactions on Instrumentation and Measurement1982，31，2： | 1 |
| 9 | Undertreatment of acute pain in the emergency department: a challenge 显示文摘 | Ruth S Riad M Sigalit K | 2005 | Int J Qual Health Care2005，17，2： | 1 |
| 10 | Numerical modeling of groundwater resource management options in the East Oweinat area, SW Egypt 显示文摘 | EBRAHEEM A M GARAMOON H K RIAD S | 2003 | Environmental Geology2003，4，1： | 1 |
| 11 | An optimization technique for iterative frequency domain deconvolution显示文摘 | BENNIA A RIAD S M | 1990 | IEEE Trans Instrum Meas1990，39，4： | 1 |
| 12 | Concise review of recent studies in vitiligo显示文摘 | Allam M Riad H | 2013 | Qatar Medical Journal2013，2013，2： | 1 |
| 13 | An optimization criterion for iterative deconvolution显示文摘 | Parruck B Riad S M | 1983 | IEEE Transactions on Instrumentation and Measurement1983，32，1： | 1 |
| 14 | Concise review of recent studies in vitiligo显示文摘 | Allam M Riad H | 2013 | Qatar Med J2013，23，2： | 1 |
| 15 | The deconvolution problem: an overview显示文摘 | Riad S M | 1986 | Proceedings of the IEEE1986，74，1： | 1 |
| 16 | New direct torque neuro-fuzzy control based SVM-three level inverter- fed induction motor 显示文摘 | RIAD T HOCINE B SALIMA M | 2010 | Control Automation and Systems2010，8，5： | 1 |
| 17 | Distribution of vesicularglutamate transporters in the human brain 显示文摘 | Vigneault t: Poirel 0 Riad M | 2015 | Front Neuroanat2015，9，： | 1 |
| 18 | Toll like receptor4 modulates survival by induction of left ventricular remodeling after myocardial infarction inmice 显示文摘 | Riad A Jager S Sobirey M | 2008 | Immunol2008，180，10： | 1 |
| 19 | Cavitation corrosion behavior of cast nickel-aluminum bronze inseawater 显示文摘 | AL-HASHEM A CACERES P G RIAD W T SHALABY H M | 1995 | Corrosion1995，51，5： | 1 |
| 20 | The deconvolution problem: an overview显示文摘 | Riad S M | 1986 | Proceedings of IEEE1986，74，1： | 1 |
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