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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Effects of social isolation on aging-induced orofacial movements in rats显示文摘 | RICARDO V P FRUSSA-FILHO R SILVA R H | 2005 | Physiology&Behavior2005，86，12： | 1 |
| 3 | Hypoxia induces H2O2production and activates antioxidant defence system in grapevine buds through mediation of H2O2and ethylene显示文摘 | Ricardo V Francisca P Sebastián R | 2012 | Experimental Botany2012，63，11： | 1 |
| 4 | Effect of copper on the photochemical efficiency,growth,and chlorophyll a biomass of natural phytoplankton assemblages Environmental显示文摘 | PATRICIA P R PATRICIA E V RICARDO B | 2006 | Toxicology and Chemistry2006，25，1： | 1 |
| 5 | Comparison of Surrogate Models in a Multidisciplinary Optimization Framework for Wing Design显示文摘 | Ricardo M P Andre R D C Curran C | 2010 | AIAA Journal2010，48，5： | 1 |
| 6 | Cadmium stress in sugar cane callus cultures: Effect on antioxidant enzymes显示文摘 | Ricardo F F Renato R F Guilherme J G P | 2002 | Plant Cell Tissue and Organ Culture2002，71，： | 1 |
| 7 | Phase diagrams of a quenched decorated Ising model with competing interactions 显示文摘 | Fittipaldi I P Ricardo de Souza J Vasconcelos dos Santos R J | 1992 | J Magn Magn Mater1992，104，107： | 1 |
| 8 | Two new species of Charinus Simon, 1892 from Brazil with biological notes (Arachnida: Amblypygi: Charinidae) 显示文摘 | Ricardo P R Glauco M Peter W | 2002 | Jour- nal of Natural History2002，36，： | 1 |
| 9 | The application of a treated sugar beet waste residue to soil Modi- ties the responses of mycorrhizal and non mycorrhizal lettuce plants to drought strcss显示文摘 | JUAN MANUEl R L MAR ADEL C P RICARDO A | 2011 | Plant Soil2011，346，12： | 1 |
| 10 | A hardware design of a massive-parallel, modular NN-based vector quantizer for real-time video coding 显示文摘 | AGUSTIN R A RAFAEL G G RICARDO C P | 2007 | Microprocessors and Microsystems2007，32，4： | 1 |
| 11 | Microsatellite analysis of the parental contribution of Piaractus mesopo- tamicus to the production of offspring in the semi-natural system of Reproduction显示文摘 | Jayme A P Ricardo P R Rodolfo N S | 2010 | Braz Arch Biol Technol2010，53，： | 1 |
| 12 | Temperature conditions in the Argentine chub mackerel ( Scomber japonicus ) fishing ground: implications for fishery management显示文摘 | Ricardo G P Maria D V Daniel R H | 2001 | Fisheries Oceanography2001，10，3： | 1 |
| 13 | Twenty - five years of seience parks in Spain towards a new model of development 显示文摘 | RICARDO M C PABLO R P | 2011 | Review of2011，2011，5： | 1 |
| 14 | Assessment of somaclonal variation in asparagus by RAPD fingerprinting and cytogenetic analyses显示文摘 | Juan P R Ricardo W M | 2001 | Sci Hortic2001，90，： | 1 |
| 15 | Updating Rurality Index for Small Areas in Spain显示文摘 | ELISA P L RICARDO C R | 2010 | Social Indicators Research2010，95，2： | 1 |
| 16 | A New One-point Quad- rature Enhanced Assumed Strain ( EAS ) Solid-shell Ele- ment with Multiple Integration Points along Thickness: Part I : Geometrically Linear Applications 显示文摘 | ALVES de SOUSA Ricardo J CARDOSO Rui P R FON- TES VALENTE Robertt A | 2006 | International Journal for Numerical Methods in Engineering2006，67，7： | 1 |
| 17 | Airport airside safety index 显示文摘 | Ricardo R P Elton F Eduardo M D | 2014 | Journal of Air Transport Management2014，18，34： | 1 |
| 18 | Development of intelligent tutoring systems using knowledge structures显示文摘 | Miguel N Ricardo R Isabel P | 2001 | Computers & Education2001，36，1： | 1 |
| 19 | Prognostic significance of p16^INK4a alterations and 9 p21 loss of heterozigosity in locally advanced laryngeal squamous cell carcinoma显示文摘 | Bazan V Zanna I Migliacca M Sannz-casla MT Maestro ML Corsale S Macaluso M Dardanoni G Restivo S Lopez Quintela P Bemaldez Ricardo Salerno S Morello V Tomasino R M Gebbia N Russo A | 2002 | Journal of Cellular Physiology2002，192，3： | 1 |
| 20 | Polymorphism in the GH1-PstI gene associated to corporal characteristics in nile tilapia strains 显示文摘 | Blanck D V Gasparino E R Ricardo P | 2009 | Pesquisa Agropecufria Brasileira2009，44，6： | 1 |
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