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| 1 | Can endoscopic submucosal dissection be safely performed in a smaller specialized clinic?显示文摘AIM:To investigate whether endoscopic submucosal dissection(ESD) can be safely performed at small clinics,such as the Shirakawa Clinic.METHODS:One thousand forty-seven ESDs to treat gastrointestinal tumors were performed at the Shirakawa Clinic from April 2006 to March 2011.The efficacy,technical feasibility and associated complications of the procedures were assessed.The ESD procedures were performed by five endoscopists.Sedation was induced with propofol for esophagogastorduodenal ESD.RESULTS:One thousand forty-seven ESDs were performed to treat 64 patients with esophageal cancer(E),850 patients with gastric tumors(G:764 patients with cancer,82 patients with adenomas and four others),four patients with duodenal cancer(D) and 129 patients with colorectal tumors(C:94 patients with cancer,21 patients with adenomas and 14 others).The en bloc resection rate was 94.3%(E:96.9%,G:95.8%,D:100%,C:79.8%).The median operation time was 46 min(range:4-360 min) and the mean size of the resected specimens was 18 mm(range:2-150 mm).No mortal complications were observed in association with the ESD procedures.Perforation occurred in 12 cases(1.1%,E:1 case,G:9 cases,D:1 case,C:1 case) and postoperative bleeding occurred in 53 cases(5.1%,G:51 cases,D:1 case,C:1 case);however,no case required either emergency surgery or blood transfusion.All of the perforations and postperative bleedings were resolved by endoscopic clipping or hemostasis.The other problematic complication observed was pneumonia,which was treated with conservative therapy.CONCLUSION:ESD can be safely performed in a clinic with established therapeutic methods and medical services to address potential complications. | Naondo Sohara Satoshi Hagiwara Riki Arai Haruhisa Iizuka Yasuhiro Onozato Satoru Kakizaki | 2013 | World Journal of Gastroenterology2013，19，4： | 15 |
| 2 | Hemorrhagic shock due to submucosal esophageal hematoma along with mallory-weiss syndrome:A case report显示文摘BACKGROUND Esophageal submucosal hematoma is a rare condition.Although the exact etiology remains uncertain,vessel fragility with external factors is believed to have led to submucosal bleeding and hematoma formation;the vessel was ruptured by a sudden increase in pressure due to nausea,and the hematoma was enlarged by antiplatelet or anticoagulant therapy.Serious conditions are rare,with a better prognosis.We present the first known case of submucosal esophageal hematoma-subsequent hemorrhagic shock due to Mallory-Weiss syndrome.CASE SUMMARY A 73-year-old female underwent endovascular treatment for an unruptured cerebral aneurysm.The patient received aspirin and clopidogrel before surgery and heparin during surgery,and was well during the surgery.Several hours after returning to the ICU,she complained of chest discomfort,vomited 500 m L of fresh blood,and entered hemorrhagic shock.Esophageal submucosal hematoma with Mallory-Weiss syndrome was diagnosed through an endoscopic examination and computed tomography.In addition to a massive fluid and erythrocyte transfusion,we performed a temporary compression for hemostasis with a Sengstaken-Blakemore(S-B)tube.Afterwards,she became hemodynamically stable.On postoperative day 1,we performed an upper gastrointestinal endoscopy and confirmed no expansion of the hematoma nor any recurring bleeding;therefore,we removed the S-B tube and clipped the gastric mucosal laceration at the esophagogastric junction.We started oral intake on postoperative day 10.The patient made steady progress,and was discharged on postoperative day 33.CONCLUSION We present the first known case of submucosal esophageal hematoma subsequent hemorrhagic shock due to Mallory-Weiss syndrome. | Jiro Oba Daisuke Usuda Shiho Tsuge Riki Sakurai Kenji Kawai Shun Matsubara Risa Tanaka Makoto Suzuki Hayabusa Takano Shintaro Shimozawa Yuta Hotchi Kenki Usami Shungo Tokunaga Ippei Osugi Risa Katou Sakurako Ito Kentaro Mishima Akihiko Kondo Keiko Mizuno Hiroki Takami Takayuki Komatsu Tomohisa Nomura Manabu Sugita | 2022 | World Journal of Clinical Cases2022，10，27： | 3 |
| 3 | Current systematic reviews and meta-analyses of COVID-19显示文摘BACKGROUND Coronavirus disease 2019(COVID-19)has left a significant impact on the world's health,economic and political systems;as of November 20,2020,more than 57 million people have been infected worldwide,with over 1.3 million deaths.While the global spotlight is currently focused on combating this pandemic through means ranging from finding a treatment among existing therapeutic agents to inventing a vaccine that can aid in halting the further loss of life.AIM To collect all systematic reviews and meta-analyses published related to COVID-19 to better identify available evidence,highlight gaps in knowledge,and elucidate further meta-analyses and umbrella reviews that are yet to be performed.METHODS We explored studies based on systematic reviews and meta-analyses with the keyterms,including severe acute respiratory syndrome(SARS),SARS virus,coronavirus disease,COVID-19,and SARS coronavirus-2.The included studies were extracted from Embase,Medline,and Cochrane databases.The publication timeframe of included studies ranged between January 01,2020,to October 30,2020.Studies that were published in languages other than English were not considered for this systematic review.The finalized full-text articles are freely accessible in the public domain.RESULTS Searching Embase,Medline,and Cochrane databases resulted in 1906,669,and 19 results,respectively,that comprised 2594 studies.515 duplicates were subsequently removed,leaving 2079 studies.The inclusion criteria were systematic reviews or meta-analyses.860 results were excluded for being a review article,scope review,rapid review,panel review,or guideline that produced a total of 1219 studies.After screening articles were categorized,the included articles were put into main groups of clinical presentation,epi-demiology,screening and diagnosis,severity assessment,special populations,and treatment.Subsequently,there was a second subclassification into the following groups:gastrointestinal,cardiovascular,neurological,stroke,thrombosis,anosmia and dysgeusia,ocular manifestations,nephrology,cutaneous manifestations,D-dimer,lymphocyte,anticoagulation,antivirals,convalescent plasma,immunosuppressants,corticosteroids,hydroxychloroquine,renin-angiotensin-aldosterone system,technology,diabetes mellitus,obesity,pregnancy,children,mental health,smoking,cancer,and transplant.CONCLUSION Among the included articles,it is clear that further research is needed regarding treatment options and vaccines.With more studies,data will be less heterogeneous,and statistical analysis can be better applied to provide more robust clinical evidence.This study was not designed to give recommendations regarding the management of COVID-19. | Mahmoud Nassar Nso Nso Mostafa Alfishawy Anastasia Novikov Salim Yaghi Luis Medina Bahtiyar Toz Sofia Lakhdar Zarwa Idrees Yungmin Kim Dawa Ongyal Gurung Raheel S Siddiqui David Zheng Mariam Agladze Vikram Sumbly Jasmine Sandhu Francisco Cuevas Castillo Nadya Chowdhury Ravali Kondaveeti Sakil Bhuiyan Laura Guzman Perez Riki Ranat Carlos Gonzalez Harangad Bhangoo John Williams Alaa Eldin Osman Joyce Kong Jonathan Ariyaratnam Mahmoud Mohamed Ismail Omran Mariely Lopez Akwe Nyabera Ian Landry Saba Iqbal Anoosh Zafar Gondal Sameen Hassan Ahmed Daoud Bahaaeldin Baraka Theo Trandafirescu Vincent Rizzo | 2021 | World Journal of Virology2021，10，4： | 2 |
| 4 | Applications of human hepatitis B virus preS domain in bio-and nanotechnology显示文摘Human hepatitis B virus(HBV) is a member of the family Hepadnaviridae, and causes acute and chronic infections of the liver. The hepatitis B surface antigen(HBs Ag) contains the large(L), middle(M), and small(S) surface proteins. The L protein consists of the S protein, pre S1, and pre S2. In HBs Ag, the pre S domain(pre S1 + pre S2) plays a key role in the infection of hepatocytic cells by HBV and has several immunogenic epitopes. Based on these characteristics of pre S, several pre S-based diagnostic and therapeutic materials and systems have been developed. Pre S1-specific monoclonal antibodies(e.g., MA18/7 and KR127) can be used to inhibit HBV infection. A myristoylated pre S1 peptide(amino acids 2-48) also inhibits the attachment of HBV to Hepa RG cells, primary human hepatocytes, and primary tupaia hepatocytes. Antibodies and antigens related to the components of HBs Ag, pre S(pre S1 + pre S2), or pre S1 can be available as diagnostic markers of acute and chronic HBV infections. Hepatocyte-targeting delivery systems for therapeutic molecules(drugs, genes, or proteins) are very important for increasing the clinical efficacy of these molecules and in reducing their adverse effects on other organs. The selective delivery of diagnosticmolecules to target hepatocytic cells can also improve the efficiency of diagnosis. In addition to the full-length HBV vector, pre S(pre S1 + pre S2), pre S1, and pre S1-derived fragments can be useful in hepatocyte-specific targeting. In this review, we discuss the literature concerning the applications of the HBV pre S domain in bio- and nanotechnology. | Riki Toita Takahito Kawano Jeong-Hun Kang Masaharu Murata | 2015 | World Journal of Gastroenterology2015，21，24： | 2 |
| 5 | A Test of the Fishbein- Ajzen Behavioral Intentions Model under Chinese Cultural Settings: Are there any Differences between PRC and Hong Kong Consumers? 显示文摘 | Chan Riky Yee - kwong and Lorett Lau | 1998 | Journal of Marketing Practice: Applied Marketing Science1998，4，3： | 1 |
| 6 | Differences in the elicitation of soluble and ionic bound enzymes in tomato leaves using chitin derivatives显示文摘 | Noah B S Natalya K Riki P | 2002 | Israel J Plant Sci2002，50，4： | 1 |
| 7 | FOXP3 expression of micrometastasis-positive sentinel nodes in breastcancer patients显示文摘 | Kazuo Matsuura Yoshiyuki Yamaguchi Akihiko Osaki Masahiro Ohara Riki Okita Akiko Emi Shigeru Murakami Koji Arihiro | 2009 | Oncology Reports2009，，5： | 1 |
| 8 | Vertical and horizontal development of the root system of carrots follow- ing green manure显示文摘 | Kristlan Thorup-krlstensen Riki van den Boogaard | 1999 | Plant and Soi11999，212，2： | 1 |
| 9 | PERCUTANEOUS NEPHROLITHOTOMY OF A PELVIC KIDNEY: A POSTERIOR APPROACH THROUGH THE GREATER SCIATIC FORAMEN显示文摘 | JAMES D. WATTERSON ANTHONY COOK RIKI SAHAJPAL JOHN BENNETT JOHN D. DENSTEDT | 2001 | The Journal of Urology2001，，1： | 1 |
| 10 | Extraction of carboxylic acids by amine-based extractants:Apparent extractant basicity according to the pH of half-neutralization显示文摘 | Riki Cabari Aharon M Eyal | 2003 | Ind Eng Chem Res2003，42，7： | 1 |
| 11 | Application of a high Resolution Inductively Coupled Plasma Mass Spectrometer to the Measurement of Long -lived Radionuclides 显示文摘 | Chang - Kyu Riki Siki | 1991 | Journal of Analytical Atomic Spectrometry1991，6，： | 1 |
| 12 | Spatial distribution and its seasonality of satellite drived vegetation index (NDVI) and climate in Siberia显示文摘 | Rikie S K Tomoyuki N K Tetsuzo Y | 2001 | International Journal of Climathology2001，21，： | 1 |
| 13 | Anatomy of the nasolabial fold: the keystone of the smiling mechanism显示文摘 | Rubin LR Mish riki Y Lee G | 1989 | Plast Reconstr Surg1989，83，： | 1 |
| 14 | Towards decentralized load balancing in a computational grid environment显示文摘 | Kai Lu Riky Subrata | 2006 | Advances in Grid and Pervasive Computing2006，，3947： | 1 |
| 15 | Vapor-liquid equilib- rium studies for the carbon dioxide- methanol system 显示文摘 | HONG Jane H KOBAYASHI Riki | 1988 | Fluid Phase Equilibria1988，41，3： | 1 |
| 16 | Adsorption equilibria in the methane- propane-silica gel system at high pressures显示文摘 | Haydel J J Kobayshi Riki | 1967 | Industrial Engineering Chemical Fundament1967，6，4： | 1 |
| 17 | The design and optimization of a series of 2-(pyridin-2-yl)-1 H -benzimidazole compounds as allosteric glucokinase activators显示文摘 | Keiji Takahashi Noriaki Hashimoto Chisato Nakama Kenji Kamata Kaori Sasaki Riki Yoshimoto Sumika Ohyama Hideka Hosaka Hiroko Maruki Yasufumi Nagata Jun-ichi Eiki Teruyuki Nishimura | 2009 | Bioorganic & Medicinal Chemistry2009，，19： | 1 |
| 18 | Strategic environmental assessment of development plans in Great Britain显示文摘 | RIKI T | 1998 | Environmental Impact Assessment Review1998，18，1： | 1 |
| 19 | Factors Influencing the Improvement of Gait Ability After Total Hip Arthroplasty显示文摘 | Riki Tanaka Masamori Shigematsu Tsutomu Motooka Masaaki Mawatari Takao Hotokebuchi | 2010 | The Journal of Arthroplasty2010，，6： | 1 |
| 20 | An Empirical Examination of the Mechanisms Mediating between High-Performance Work Systems and the Performance of Japanese Organizations 显示文摘 | Riki Takeuchi | 2007 | Journal of Applied Psychology2007，92，4： | 1 |
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