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| 1 | LncRNA-encoded peptides: More than translational noise?显示文摘 | Nathalie Rion Markus A R #x000FC egg | 2017 | Cell Research2017，27，5： | 8 |
| 2 | 5~60岁人群伤寒Vi多糖疫苗和A群脑膜炎球菌多糖疫苗大规模接种结果分析显示文摘为考核国产伤寒Vi多糖疫苗在现场试验的效果 ,以A群脑膜炎球菌多糖疫苗为对照 ,对广西壮族自治区河池市城市和农村的 5~ 6 0岁居民进行了一次大规模接种。结果显示 :应接种对象 1180 71人 ,实际接种 92 4 76人 ,接种率为 78 32 % ,其中伤寒Vi多糖疫苗为 76 87% ,A群脑膜炎球菌多糖疫苗为 79 6 9% ;接种率最高的组群接种率为 92 4 8% ,最低为 6 5 2 0 %。按城乡划分 ,城区的接种率为 77 2 9% ,农村的接种率为 80 5 8% ,组群接种率的高低分布无明显的地理性差异。 5~ 9岁接种率最高为 89 6 5 % ,2 0~ 2 9岁接种率最低为 6 9 0 7% ;男女接种率分别为79 0 7%和 82 11%。有 6 6人被观察到或报告出现不良反应 ,不良反应发生率为 71 37/ 10万。表明两种疫苗的安全性好。在大规模疫苗接种中 ,充分发挥当地干部的宣传组织作用 ,并把接种的有关信息提前通知当地居民 ,对于提高接种率十分重要。补漏接种能使接种率低的组群得到显著的提高。在大规模疫苗接种中必须严格遵守安全注射操作程序 ,避免发生不安全注射事故。两种疫苗的平均接种率、年龄别接种率、性别接种率、组群接种率的地理分布均达到了较好均衡性 ,是可比的 。 | 杨进 司国爱 曾竣 张杰 梁贵臣 梁大斌 廖和壮 李翠云 黄焕新 董柏青 杨宏徽 Rion Leon Ochiai Carolina Danovaro Ali Mohammad Camilo J Acosta | 2004 | 中国计划免疫2004，10，4： | 6 |
| 3 | Shear wave elastography in hepatitis C patients before and after antiviral therapy显示文摘AIM To investigate shear wave(SW) propagation velocity in patients with untreated hepatitis C and patients with sustained virological response(SVR). METHODS A total of 136 hepatitis C patients [85 patients who had not received antiviral therapy(na?ve group) and 51 patients who had received antiviral therapy and subsequently achieved SVR of at least 24 wk(SVR group)] and 58 healthy volunteers and outpatients without liver disease(control group) underwent evaluation of liver stiffness by SW elastography(SWE). Various parameters were evaluated in the chronic hepatitis C patients at the time of SWE.RESULTS SW propagation velocity(Vs) was 1.23 ± 0.14 m/s in the control group, 1.56 ± 0.32 m/s in the SVR group, and 1.69 ± 0.31 m/s in the na?ve group. Significant differences were seen between the control group and the SVR group(P = 0.0000) and between the SVR group and the na?ve group(P = 0.01417). All four fibrosis markers were higher in the na?ve group than in the SVR group. In the na?ve group, Vs was positively correlated with alanine aminotransferase(ALT)(r = 0.5372), α feto protein(AFP)(r = 0.4389), type Ⅳ collagen(r = 0.5883), procollagen Ⅲ peptide(P-Ⅲ-P)(r = 0.4140), hyaluronic acid(r = 0.4551), and Mac-2 binding protein glycosylation isomer(M2BPGi)(r = 0.6092) and negatively correlated with albumin(r =-0.4289), platelets(r =-0.5372), and prothrombinactivity(r =-0.5235). On multiple regression analysis, Vs was the most strongly correlated with ALT(standard partial regression std β = 0.4039, P = 0.00000). In the SVR group, Vs was positively correlated with AFP(r = 0.6977), type IV collagen(r = 0.5228), P-Ⅲ-P(r = 0.5812), hyaluronic acid(r = 0.5189), and M2BPGi(r = 0.6251) and negatively correlated with albumin(r =-0.4283), platelets(r =-0.4842), and prothrombin activity(r =-0.4771). On multiple regression analysis, Vs was strongly correlated with AFP(standard partial regression std β = 0.5953, P = 0.00000) and M2BPGi(standard partial regression std β = 0.2969, P = 0.03363).CONCLUSION In hepatitis C patients, liver stiffness is higher in treatment-na?ve patients than in those showing SVR. SWE may be a predictor of hepatocarcinogenesis in SVR patients. | Toshikuni Suda Osamu Okawa Rion Masaoka Yoshinori Gyotoku Naohiko Tokutomi Yasumi Katayama Masaya Tamano | 2017 | World Journal of Hepatology2017，9，1： | 4 |
| 4 | 组群随机试验在伤寒疫苗效果观察中的应用研究显示文摘目的 用组群随机试验实现伤寒Vi疫苗效果观察的研究设计和实施应用。方法 采用组群随机试验方法确定试验组和对照组所需样本量 ,并组织实施大规模疫苗接种 ,在试验组接种伤寒Vi疫苗、对照组接种流脑疫苗。结果 根据组群随机试验方法计算共需要观察对象为 96 12 1人 ,分为 10 8个组群。根据组群大小、地理位置 (城乡 )及性质 (学校、机关、厂矿、人口特征 )分层配对 ,确定试验组分为 5 3个组群共 4 4 0 5 4人 ,对照组为 5 4个组群共 4 84 2 2人。对两组间各主要混杂因子 (年龄、性别、居住地点、主要人群的经济收入、受教育程度、主要职业 )等进行分析 ,发现两组之间总体相差不大 ,具有较好的均衡性与可比性。结论 组群随机抽样法应用于大规模疫苗效果观察试验 ,能较好地控制组间混杂因子 ,使干预的实际效果得到科学的评价 ;实施也比较简单 ,被干预对象容易接受 ,可行性高。 | 董柏青 杨进 唐振柱 杨宏徽 曾竣 张杰 王鸣柳 梁贵臣 司国爱 李翠云 梁大斌 廖和壮 Rion Leo nOchiai Ali Mohammad Camilo J Acosta John Clemens | 2005 | 中华流行病学杂志2005，26，2： | 3 |
| 5 | Evolutionary biology of starvation resistance:What we have learned from Drosophila显示文摘 | Rion S Kawecki T J | 2007 | Journal of Evolutionary Biology2007，20，5： | 1 |
| 6 | Reduction of infarct size and postischemic inflammation from ATL-146e,a highly selective adenosine A2A receptor agonist,in reperfusd canine myocardium显示文摘 | Glover DK Rion LM Ruiz M | 2005 | Am J Pbysiol Heart Cite Pbysiol2005，288，4： | 1 |
| 7 | Human T-cell clones against T gondii production of interferon-gamma显示文摘 | Saavedra R Hérion P | 1991 | Parasitol Res1991，77，： | 1 |
| 8 | Operation and control of HVDC-conneeted offshore wind farm 显示文摘 | MUYEEN S M TAKAHASHI Rion TAMURA Junji | 2010 | IEEE Trans on Sustainable Energy2010，1，1： | 1 |
| 9 | Evolutionary biology of starvation resistance: what we have learned from Drosophila 显示文摘 | Rion S Kawichi T J | 2007 | Journal of Evolutionary Biology2007，20，5： | 1 |
| 10 | Anti-atherosclerotic effect of amlodipine,alone and in combination with atorvastatin,in APOE3-Leiden/hCRP transgenic mice显示文摘 | Rion A de Maat M Jukema W | | 0，，01： | 1 |
| 11 | Operation and control of HVDC-Connected offshore wind farm显示文摘 | Muyeen S M Takahashi Rion Tamura Junji | 2010 | IEEE Transactions on Sustainable Energy2010，，1： | 1 |
| 12 | The Use of Silicon Carbide as a Tritium Permeation Barrier 显示文摘 | Rion Causey A | 1995 | Nuclear Materials1995，，： | 1 |
| 13 | Prediction of the adhesivefillet size for skin to honeycomb core bonding in ultra-lightsandwich structures 显示文摘 | Rion J Leterrier Y Manson J E | 2008 | Composites Part A2008，39，9： | 1 |
| 14 | Operation and control of HVDC-connected offshore wind farm显示文摘 | S M Muyeen Rion Takahashi Junji Tamura | 2010 | IEEE Transactions on Sustainable Energy2010，1，1： | 1 |
| 15 | What is effects of adenosine显示文摘 | Rion A CataonK | 2003 | Flow and Metabolism2003，19，3： | 1 |
| 16 | Mdm-2 Proto-oncogene Εxpression and Ρrognosis in Εarly Carcinoma of the Uterine Cervix显示文摘 | Rion G Barrois M Le M G | 1987 | Lancet1987，，1： | 1 |
| 17 | Human papillomaviros(HPV)genotyping by HPV DNA chip in cervical cancer and precancerous lesions显示文摘 | Lee GY Kim SM Rion SY | 2012 | Int J Gynecol Cancer2012，15，1： | 1 |
| 18 | Prediction of the adhesive fillet size for skin to honeycomb core bonding in ultra-light sandwich struc- tures显示文摘 | Rion J Leterrier Y Manson J E | 2008 | Composites Part A2008，，39： | 1 |
| 19 | Bone-marrow-derived stem cells do not reconstitute spermatogenesis in vivo显示文摘 | Lassalle B Monthon M A Rion L | 2008 | Stem Cells2008，26，5： | 1 |
| 20 | A determination method of power rating of energy storage system for smoothing wind generator output 显示文摘 | Rion Takahashi Junji Tamura etal | 2010 | IEEE Transactions on Power Systems2010，34，1： | 1 |
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