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| 1 | Helical tomotherapy and volumetric modulated arc therapy:New therapeutic arms in the breast cancer radiotherapy显示文摘AIM To analyse clinical and dosimetric results of helical tomotherapy(HT) and volumetric modulated arc therapy(VMAT) in complex adjuvant breast and nodes irradiation.METHODS Seventy-three patients were included(31 HT and 42 VMAT). Dose were 63.8 Gy(HT) and 63.2 Gy(VMAT) in the tumour bed, 52.2 Gy in the breast, 50.4 Gy in supraclavicular nodes(SCN) and internal mammary chain(IMC) with HT and 52.2 Gy and 49.3 Gy in IMC and SCN with VMAT in 29 fractions. Margins to particle tracking velocimetry were greater in the VMAT cohort(7 mm vs 5 mm).RESULTS For the HT cohort, the coverage of clinical target volumes was as follows: Tumour bed: 99.4% ± 2.4%; breast: 98.4% ± 4.3%; SCN: 99.5% ± 1.2%; IMC:96.5% ± 13.9%. For the VMAT cohort, the coverage was as follows: Tumour bed: 99.7% ± 0.5%, breast: 99.3% ± 0.7%; SCN: 99.6% ± 1.4%; IMC: 99.3% ± 3%. For ipsilateral lung, Dmean and V20 were 13.6 ± 1.2 Gy, 21.1% ± 5%(HT) and 13.6 ± 1.4 Gy, 20.1% ± 3.2%(VMAT). Dmean and V30 of the heart were 7.4 ± 1.4 Gy, 1% ± 1%(HT) and 10.3 ± 4.2 Gy, 2.5% ± 3.9%(VMAT). For controlateral breast Dmean was 3.6 ± 0.2 Gy(HT) and 4.6 ± 0.9 Gy(VMAT). Acute skin toxicity grade 3 was 5% in the two cohorts.CONCLUSION HT and VMAT in complex adjuvant breast irradiation allow a good coverage of target volumes with an acceptable acute tolerance. A longer follow-up is needed to assess the impact of low doses to healthy tissues. | Olivier Lauche Youlia M Kirova Pascal Fenoglietto Emilie Costa Claire Lemanski Celine Bourgier Olivier Riou David Tiberi Francois Campana Alain Fourquet David Azria | 2016 | World Journal of Radiology2016，8，8： | 7 |
| 2 | 工业科学课程实践环节考核方法与内涵显示文摘工业科学是法国预科学校工程科学与物理(PSI)专业的必修课程,也是法国工程师大学校(Grandes Ecoles)入学考试科目之一,考生需要完成该课程理论和实验两部分的独立考试。在4个小时的实验考试期间,考生需要针对某个工程实际问题,依托实验设备,完成分析、计算、仿真、实验、口头陈述等多项任务;考试成绩则依据考生在考试过程中展示出的理解和分析能力、沟通交流和表达能力以及解决复杂工程问题的综合能力而定。该考评方法也在我院(北京航空航天大学中法工程师学院)工业科学课程的实验课中得到了应用。结果表明,这种注重过程和综合能力评价的考核方式和评价方法,可以较为客观有效地评价学生的综合实验能力,其考核标准可为我国实践教学环节的考核体系改革提供借鉴。 | 徐平 Hervé RIOU | 2019 | 北京航空航天大学学报(社会科学版)2019，32，4： | 2 |
| 3 | Usefulness of procalcitonin as a marker of systemic infection in emergency department patients: a prospective study 显示文摘 | Hausfater P Garric S Ayed SB Rosenheim M Bernard M Riou B | 2002 | Clin Infect Dis2002，34，7： | 1 |
| 4 | C-myc proto oncogene expression and prognosis in early carcinoma of the uterine cervix 显示文摘 | Riou G Barrios M George M | 1987 | Lancet1987，4，1： | 1 |
| 5 | Intravenous morphine titration显示文摘 | AUBRUN F VALADE N RIOU B | 2004 | Ann Fr Anesth Reanim2004，23，： | 1 |
| 6 | The Fourier version of the variational theory of complex rays for medium-frequency acoustics显示文摘 | Kovalevsky L Ladevèze P Riou H | 2012 | Computer Methods in Applied Mechanics and Engineering2012，，： | 1 |
| 7 | Accuracy of the cerebrospinal fluid results to differentiate bacterial from non bacterial meningitis, in case of negative gram-stained smear显示文摘 | Patrick Ray Ghislaine Badarou-Acossi Alain Viallon David Boutoille Martine Arthaud David Trystram Bruno Riou | 2007 | American Journal of Emergency Medicine2007，，2： | 1 |
| 8 | Cell senescence and telomere shortening induced by a new series of specific G-quadruplex DNA ligands显示文摘 | Guittat L Mailliet P | 2002 | Proc Natl Acad Sci USA2002，99，5： | 1 |
| 9 | Fast adaptive eigenvalue decomposition:a maximum likelihood approach显示文摘 | CHONAVEL T CHAMPAGNE B RIOU C | 2003 | Signal processing2003，83，： | 1 |
| 10 | A breathing hybrid organic-inorganic solid with very large pores and high magnetic characteristics显示文摘 | Barthelet Karin Marrot Jereme Riou Didier Ferey Gorard | 2002 | Angewandte Chemic2002，114，： | 1 |
| 11 | A breathing hybrid organic–inorganic solid with very large pores and high magnetic characteristics显示文摘 | BARTHELET K MARROT J RIOU D | 2002 | Angew Chem Int Ed2002，41，： | 1 |
| 12 | Detection of telomerase inhibitors based on G-quadruplex ligands by a modified telomeric repeat amplification protocol assay显示文摘 | Mergny JL Riou JF | 2002 | Cancer Res2002，62，15： | 1 |
| 13 | Synthesis and evaluation of new 6-amino-substituted benzo phenanthridine derivatives显示文摘 | Janin YL Croisy A Riou JF | 1993 | J Med Chem1993，36，23： | 1 |
| 14 | Organ biodistribution and myocardial uptake, washout, and redistribution kinetics of Tc-99m N-DBODC5 when injected during vasodilator stress in canine models of coronary stenose显示文摘 | Hatada K Ruiz M Riou L M | 2006 | J Nucl Cardiol2006，13，： | 1 |
| 15 | Cellular up-take and efflux of docetaxel (Taxotere) and paclitaxel ( Taxol in P388 cell line显示文摘 | RIOU J F PETITGENET O COMBEAU C | 1994 | Proc Am Assoc Cancer Res1994，35，： | 1 |
| 16 | Isolation and characterization of a cDNA encoding Arabiclopsis thaliana mevalonate kinase by genetic complementation in yeast 显示文摘 | Riou C Tourte Y Lacroute F | 1994 | Gene1994，148，： | 1 |
| 17 | Pulmonarythromboendarterectomy for chronic thromboembolic obstruction ofthe pulmonary artery in piglets显示文摘 | Fadel E Riou JY Mazmanian M | 1999 | J Thorac Cardiovasc Surg1999，117，4： | 1 |
| 18 | Results of a 12-- month qualitycircle prescribing improvement programme for GPs 显示文摘 | Riou F Piette C Durand G | 2007 | Br J GenPract2007，57，540： | 1 |
| 19 | Altered cell cycle distribution, hyperplasia, and inhibited differertiation in Arubidopsis caused by the D-type cyclin CYCD3显示文摘 | WITTE W RIOU KHAMLICHI C SCOFIELD S | 2003 | Plant cell2003，15，1： | 1 |
| 20 | Fast adaptive eigenvaluede composition:A maximum likelihood approach显示文摘 | CHONAVEL T CHAMPAGNE B RIOU C | 2003 | Signal Process2003，51，4： | 1 |
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