| 1 | Diagnosis, treatment, and misdiagnosis analysis of 28 cases of central nervous system echinococcosis显示文摘Background:To explore central nervous system(CNS)involvement in this disease,from the perspectives of diagnosis,treatment,and misdiagnosis Methods:Twenty-eight patients with CNS echinococcosis were included in this retrospective study,including 18 males(64.3%)and 10(35.7%)females.The average age of all the patients were 23.5 years(ranged 4–60 years).Twenty-three(23)patients(82.1%)received the first surgical resection in our hospital.Five(5)patients(17.9%)gave up surgical treatment for multiple-organ hydatidosis and previous surgery history at other hospitals,and albendazole was applied for a long-term(3–6 months)adjunct therapy for the 5 patients.The average follow-up time was 8 years.Results:For the 28 patients,23 cases received surgical treatments,and the diagnosis was confirmed by pathological examinations.The diagnosis of 4 cases of brain echinococcosis and 2 cases of spinal cord echinococcosis could not be confirmed,resulting in a misdiagnosis rate of 21.4%(6/28).For the pathological examination,a total of 17 cases were infected with Echinococcus granulosus(including 2 cases of spinal cord echinococcosis),and 6 cases were infected with Echinococcus alveolaris.Conclusion:The diagnosis should be specifically considered in endemic regions.The clinical features of CNS hydatidosis were intracranial space-occupying lesions.For the treatment,the surgical removal of cysts should be necessary.In addition,the adjuvant therapy with drug and intraoperative prophylaxis is also suggested.The misdiagnosis may have resulted from atypical clinical features and radiographic manifestations,as well as the accuracy of hydatid immunologic test. | Guojia Du Yandong Li Pan Wu Xin Wang Riqing Su Yandong Fan Dangmurenjiafu Geng | 2021 | Chinese Neurosurgical Journal2021，7，4： | 3 |
| 2 | Vinyl chloride accident unleashes a toxic legacy显示文摘A railroad accident on February 3,2023,led to the release and combustion of 115,580 gallons,equivalent to over 437,000 L,of vinyl chloride monomer(VCM)in East Palestine,Ohio[1].This monomer is used in polyvinyl chloride(PVC)production,and its burning produces additional toxins such as hydrochloric acid and lethal phosgene,known as a notorious chemical weapon during World War I[2].Acute exposure to these chemicals causes immediate adverse effects on local ecosystems,including the deaths of wild and farmed animals and pets. | Chengjun Li Peng Gao Riqing Yu Huan Zhong Mengjie Wu Su Shiung Lam Christian Sonne | 2023 | Environmental Science and Ecotechnology2023，，2： | 0 |
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