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| 1 | Validation of Predictive Value of Patterns of Nonadherence to Antiplatelet Regimen in Stented Patients Thrombotic Risk Score in Chinese Population Undergoing Percutaneous Coronary Intervention:A Prospective Observational Study显示文摘Background:The patterns of nonadherence to antiplatelet regimen in stented patients (PARIS)thrombotic risk score are a novel score for predicting the risk of coronary thrombotic events (CTEs)after percutaneous coronary intervention (PCI)with drug-eluting stents. However,the prognostic value of this score has not been fully evaluated in non-Euro-American PCI populations. Methods:We performed a prospective,observational study of 10,724 patients who underwent PCI in Fuwai hospital,China and evaluated the PARIS thrombotic risk score's predictive value of CTEs in the PCI population.The area under the receiver operating characteristic curve (AUROC)was used to assess the predictive value of the PARIS score for CTE. Results:Among 9782 patients without in-hospital events,a total of 95 CTEs occurred during the 2-year follow-up.The PARIS score was significantly higher in patients with CTEs (3.384-2.04)compared with patients without events (2.53±1.70,P <0.001). According to the risk stratification of the PARIS thrombotic score,the risk of CTEs in the high-risk group was 3.14 times higher than that in the low-risk group (hazard ratio [HR],3.14;95% confidence interval [CI],1.92-5.13;P <0.001).However,the risk of CTEs in the intermediate-risk and low-risk groups was not significant (HR,1.39;95% CI,[0.86-2.24];P =0.184).The PARIS score showed prognostic value in evaluating CTEs in the overall population (AUROC,0.621;95% CI,0.561-0.681),the acute coronary syndrome (ACS)population (AUROC,0.617;95% CI,0.534-0.700;P =0.003),and the non-ACS population (AUROC,0.647;95% CI,0.558-0.736;P =0.001). Conclusions:In a real-world Chinese population,the PARIS thrombotic risk score shows a modest prognostic value for CTEs in patients after PCI.This score also has a predictive value for CTEs in the ACS and non-ACS subgroup populations. | Xue-Yan Zhao Jian-Xin Li Xiao-Fang Tang Jing-Jing Xu Ying Song Lin Jiang Jue Chen Lei Song Li-Jian Gao Zhan Gao Shu-Bin Qiao Yue-Jin Yang Run-Lin Gao Ro Xu Jin-Qing Yuan | 2018 | Chinese Medical Journal2018，，22： | 4 |
| 2 | Differential expression of nuclear retinoid receptors in normal, premalignant, and malignant head and neck tissues显示文摘 | Xiao-chun XU Jae Y Ro Jin S Lee | 1994 | Cancer Research1994，54，： | 1 |
| 3 | Seroprev alence of know n and putative hepatitis markers in United States blood donors with ALT levels at least 120 IU per L 显示文摘 | T ro uer n JJ Wolf JS Xu YL | 2001 | Transfusion2001，41，6： | 1 |
| 4 | Differential expression of nuclear retinoic acid receptors in normal,premalignant,and malignant head and neck tissues显示文摘 | Xu XC Ro JY Lee JS | | 0，，： | 1 |
| 5 | Effect of a herbal extract on the bone density strength and morkersaf bene turnoner of matune overiectomized rats显示文摘 | XU M Dick Iana M Ro Day | 2003 | Am J Chin2003，31，1： | 1 |
| 6 | GPR56 and TG2:possible roles in suppression of tumor growth by the microenvironment显示文摘 | Xu L Hynes RO | 2007 | Cell Cycle2007，6，2： | 1 |
| 7 | A distinct lineage of influenza A virus from bats 显示文摘 | Tong S Li Y Rivailler P Conrardy C Castillo DA Chen LM Recuenco S Ellison JA Davis CT York IA Turmelle AS Moran D Rogers S Shi M Tao Y Weil MR Tang K Rowe LA Sammons S Xu X France M Lindblade KA Cox NJ Anderson LJ Rupprecht CE Donis RO | 2012 | Proc Natl Acad Sci USA2012，109，11： | 1 |
| 8 | Effect of tea and chlorophyllin on the mutagcnicity of N–hydroxy–IQ:Studies of enzyme inhibition molecular complex for mation and degradation/scavenging of the active metabolities显示文摘 | Judith H Xu M R Ro derrick D | 1997 | Environ Mol Mutagen1997，30，46： | 1 |
| 9 | GPR56 and TG2: possible roles in suppression of tumor growth by the microenvironment显示文摘 | Xu L Hynes RO | 2007 | Cell Cycle2007，6，2： | 1 |
| 10 | Effect of Tea and Chlomphyllin on the Mutagcnicity of N-bydroxy-IQ:Studies of Enzyme Inhibition Molecular Complex for Mation and Degradation/Scavenging of the Active Metabolities显示文摘 | Judith H Xu M R Ro derrick D | 1997 | Environ Mol Mutagen1997，30，： | 1 |
| 11 | GPR56 and TG2 Possible Roles in Suppression of Tumor Growth by the Microenviron- ment显示文摘 | Xu L Hynes RO | 2007 | Cell Cycle2007，6，2： | 1 |
| 12 | Differential expression of nuclear retinoid receptors in normal, premalignant, and malignant head and neck tissues 显示文摘 | Xu Xiao-chun Ro JY Lee JS | 1994 | Cancer Res1994，54，13： | 1 |
| 13 | East Asian VLBI Network observations of active galactic nuclei jets:imaging with KaVA+Tianma+Nanshan显示文摘The East Asian Very Long Baseline Interferometry(VLBI) Network(EAVN) is a rapidly evolving international VLBI array that is currently promoted under joint efforts among China,Japan and Korea.EAVN aims at forming a joint VLBI Network by combining a large number of radio telescopes distributed over East Asian regions.After the combination of the Korean VLBI Network(KVN) and the VLBI Exploration of Radio Astrometry(VERA) into Ka VA,further expansion with the joint array in East Asia is actively promoted.Here we report the first imaging results(at 22 and 43 GHz) of bright radio sources obtained with Ka VA connected to Tianma 65-m and Nanshan 26-m Radio Telescopes in China.To test the EAVN imaging performance for different sources,we observed four active galactic nuclei(AGN) having different brightness and morphology.As a result,we confirmed that the Tianma 65-m Radio Telescope(TMRT) significantly enhances the overall array sensitivity,a factor of 4 improvement in baseline sensitivity and 2 in image dynamic range compared to the case of Ka VA only.The addition of the Nanshan 26-m Radio Telescope(NSRT) further doubled the east-west angular resolution.With the resulting high-dynamic-range,high-resolution images with EAVN(Ka VA+TMRT+NSRT),various fine-scale structures in our targets,such as the counter-jet in M87,a kink-like morphology of the 3 C 273 jet and the weak emission in other sources are successfully detected.This demonstrates the powerful capability of EAVN to study AGN jets and to achieve other science goals in general.Ongoing expansion of EAVN will further enhance the angular resolution,detection sensitivity and frequency coverage of the network. | 崔玉竹 Kazuhiro Hada Motoki Kino Bong-Won Sohn Jongho Park Hyun-Wook Ro Satoko Sawada-Satoh Wu Jiang Lang Cui Mareki Honma 沈志强 Fumie Tazaki 安涛 Ilje Cho Guang-Yao Zhao Xiao-Peng Cheng Kotaro Niinuma Kiyoaki Wajima Ying-Kang Zhang Noriyuki Kawaguchi Juan-Carlos Algaba Shoko Koyama Tomoya Hirota Yoshinori Yonekura Nobuyuki Sakai Bo Xia Yong-Bin Jiang Lin-Feng Yu Wei Gou Ju-Yeon Hwang Yong-Chen Jiang Yun-Xia Sun Dong-Kyu Jung Hyo-Ryoung Kim Jeong-Sook Kim Hideyuki Kobayashi Jee-Won Lee Jeong-Ae Lee Hua Zhang Guang-Hui Li Zhi-Qiang Xu Peng Li Jung-Hwan Oh Se-Jin Oh Chung-Sik Oh Tomoaki Oyama Duk-Gyoo Roh Katsunori-M.Shibata 郭文 Rong-Bing Zhao Wei-Ye Zhong Jin-Qing Wang Wen-Jun Yang 闫浩 Jae-Hwan Yeom Bin Li 李笑飞 Jian-Ping Yuan Jian Dong Zhong Chen Kazunori Akiyama Keiichi Asada Do-Young Byun Yoshiaki Hagiwara Jeffrey Hodgson Tae-Hyun Jung Kee-Tae Kim Sang-Sung Lee Kunwoo Yi Qing-Hui Liu Xiang Liu Ru-Sen Lu Masanori Nakamura Sascha Trippe Na Wang Xue-Zheng Wang 张波 | 2021 | Research in Astronomy and Astrophysics2021，21，8： | 0 |
| 14 | Détection de la Mutation du Gène hMLH1 Dans le Cancer Colo-rectal Parélectrophorèse Capilailre Associée a la Fluorescence Laser-Induite显示文摘Résumé: Objectif Lobjectif de ce travail est detablir une méthode danalyse du polymorphisme de la conformation monochaine (PCMC), capable de détecter la mutation ponctuelle du gène hMLH1 dans le cancer colique en utilisant l l ctrophor se capillaire associée a la fluorescence laser-induite (FLI-EC). Méthodes Les exons 12 du gène hMLH1 du sang périphérique de 42 patients de cancer colo-rectal sporadique et 20 sujets sains témoins sont amplifiés par la PCR. Le PCMC des produits du PCR est analysé par FLI-EC. Les échantillons anormaux ont été confirmés par séquen age EC. Les effets de la concentration du milieu (LPA), de la température de séparationet du voltage de séparation sur le comportement de EC ont été aussi etudiés. Résultats Lanalyse de PCMC par la methode FLI-EC a retrouvé une mutation hétérozygote chez 4 des 42 patients. La mutation ponctuelle de T1151A a été objectivée par la séquen age EC de ces échantillons, aucune mutation na été retrouvée chez les 20 sujets sains témoins. La séparation des pics dADN monochainaux a été facilitée par une légère augmentation de la concentration de LPA (4%-6%), une légère baisse de la température de séparation (20℃) et une légère élévation du voltage de séparation (9kV). Conclusion Une concentration adéquate de LPA, une température de séparation appropriée et un voltage de séparation bien approprié améliorent considérablement l’efficacité du FLI-EC. L’application de cette méthode pour détecter la mutation ponctuelle du gène hMLH1 est d’une rapidité, d’une efficacité, et d’uneéreproductivit consid rables. Cette méthode de réalisation facile reste très prometteur pour le dépistage rapide et massive des mutations génétiques. | FENG Bo, ZHENG Min-hua, LU Ai-guo, LI Jian-wen, JIANG Wei-na, WANG Ming-liang, MA Jun-jun, DONG FengService de chirurgie, l’hoital Ruijin, l’université médicale numéro 2 de Shanghai, Institut Chirurgical Digestif de Shanghai, Shanghai 200025, ChineSHI Xian-zhe, XU Guo-wangInstitut physico-chimique de Dalian, Dalian 116011, Chine | 2006 | 上海交通大学学报(医学版)2006，26，4： | 0 |
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