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7篇 您的检索式:作者名="Roberta Mazzucchelli"
    题名 作者 年代 出处 被引量
1α -methylacyl-CoA racemase (P504S)/34 β E12/p63 triple cocktail stain in prostatic adenocarcinoma after hormonal therapy显示文摘Ming-Tse Sung Zhong Jiang Rodolfo Montironi Gregory T. MacLennan Roberta Mazzucchelli Liang Cheng 2007Human Pathology2007,,2:1
2Overexpression of ELAV-like Protein HuR is Associated with Increased COX-2 Expression in Atrophy, High-grade Prostatic Intraepithelial Neoplasia, and Incidental Prostate Cancer in Cystoprostatectomies显示文摘Francesca Barbisan Roberta Mazzucchelli Alfredo Santinelli Antonio Lopez-Beltran Liang Cheng Marina Scarpelli Francesco Montorsi Rodolfo Montironi 2008European Urology2008,,1:1
3Bicalutamide 50 mg monotherapy in patients with isolated high-grade PIN: findings in repeat biopsies at 6 months显示文摘Aldo V Bono Roberta Mazzucchelli 2007J Clin Pathol2007,60,:1
4Pathological issues in biopsy specimens of men with prostate cancer eligible for active surveillance显示文摘Roberta Mazzucchelli Andrea Benedetto Galosi Antonio Lopez -Beltran 2014Associazione Ricerche in Urologia2014,86,4:1
5Identification of BRAF V600E mutation in odontogenic tumors by high-performance MALDI-TOF analysis显示文摘Odontogenic tumors are rare lesions with unknown etiopathogenesis.Most of them are benign,but local aggressiveness,infiltrative potential,and high recurrence rate characterize some entities.The MAP-kinase pathway activation can represent a primary critical event in odontogenic tumorigenesis.Especially,the BRAF V600E mutation has been involved in 80%–90%of ameloblastic lesions,offering a biological rationale for developing new targeted therapies.The study aims to evaluate the BRAF V600E mutation in odontogenic lesions,comparing three different detection methods and focusing on the Sequenom MassARRAY System.81 surgical samples of odontogenic lesions were subjected to immunohistochemical analysis,Sanger Sequencing,and Matrix-Assisted Laser Desorption/Ionization-Time of Flight mass spectrometry(Sequenom).The BRAF V600E mutation was revealed only in ameloblastoma samples.Moreover,the presence of BRAF V600E was significantly associated with the mandibular site(ρ=0.627;P value<0.001)and the unicystic histotype(ρ=0.299,P value<0.001).However,any significant difference of 10-years disease-free survival time was not revealed.Finally,Sequenom showed to be a 100%sensitive and 98.1%specific,suggesting its high-performance diagnostic accuracy.These results suggest the MAP-kinase pathway could contribute to ameloblastic tumorigenesis.Moreover,they could indicate the anatomical specificity of the driving mutations of mandibular ameloblastomas,providing a biological rational for developing new targeted therapies.Finally,the high diagnostic accuracy of Sequenom was confirmed.Lucrezia Togni Antonio Zizzi Roberta Mazzucchelli Andrea Santarelli Corrado Rubini Marco Mascitti 2022International Journal of Oral Science2022,14,2:0
6Contemporary grading of prostate cancer:2017 update for pathologists and clinicians显示文摘The Gleason grading system for prostate cancer(PCa)was.developed in the 1960s by DF Gleason.Due to changes in PCa detection and treatment,the application of the Gleason grading system has changed considerably in pathology routine practice.Two consensus conferences were held in 2005 and in 2014 to update PCa Gleason grading.This review provides a summary of the changes in the grading of PCa from the original Gleason grading system to the prognostic grade grouping,as well as a discussion of the clinical significance of the percentage of Gleason patterns 4 and 5.Silvla Gasparrini Alessia Clmadamore Marina Scarpelli Francesco Massari Andrea Doria Roberta Mazzucchelli Liang Cheng Antonio Lopez-Beltran Rodolfo Montironi 2019Asian Journal of Andrology2019,21,1:0
7Somatostatin receptor subtypes in hormone-refractory (castration-resistant) prostatic carcinoma显示文摘这研究的目的是检验织物表示和 somatostatin 受体(SSTR ) 的本地化在荷尔蒙倔强(HR ) 前列腺癌症(PCa ) 。五 SSTR 与格利森一起在 20 激进的前列腺切除术(RP ) immunohistochemically 被评估分数(GS ) 3+3=6 PCa 在有 GS 4+4=8 和 4+5=9 PCa 的 20 RP,并且有 HR PCa 的前列腺标本的 20 经尿道的切除术。在细胞质的吝啬的价值(所有五 SSTR 被表示),膜(仅仅 SSTR3 和 SSTR4 被表示)并且原子核(仅仅 SSTR4 和 SSTR5 被表示)在 HR 的腺, PCa 是0%比在另外的二个组降低的 20 鈥?,是统计上重要的差别。所有五 SSTR 在光滑的肌肉和 HR PCa 的 endothelial 房间被表示,比在另外的二个组低的吝啬的价值。在结论,这研究与荷尔蒙敏感的 PCa 相比在 HR PCa 在各种各样的织物部件在五 SSTR 的表示和本地化上扩展我们的知识。Roberta Mazzucchelli Doriana Morichetti Marina Scarpelli Aldo V Bono Antonio Lopez-Beltran Liang Cheng Ziya Kirkali Rodolfo Montironi 2011Asian Journal of Andrology2011,13,2:0
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