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| 1 | Implications of apoptotic cell death regulation in cancer therapy 显示文摘 | McDonnel LTJ Meyn RE Robertson LE | 1995 | Semin Cancer Biol1995，6，1： | 1 |
| 2 | Bcl-2 epression in choronic lymphocytic loukemia and its correlation with the induction if apoptosis and clinical outcome显示文摘 | Robertson LE Plunkett W Me Connell K | 1996 | Leukemia1996，10，： | 1 |
| 3 | Alterations in leucocyte teta - receptor affinity with ageing 显示文摘 | Feldman RD Limbird LE Nadeau J Robertson D Wood AJJ | 1984 | N Engl J Med1984，310，： | 1 |
| 4 | Response to suxamethonium during propofol-fentanyl-N2O/O2 anaesthesia in a patient with active myasthenia gravis recieving longterm anticholinesterase therapy显示文摘 | Vanlinthout LE Robertson EN Booi JLH | 1994 | Anaesthesia1994，49，： | 1 |
| 5 | Implications of apoptotic cell death regulation in cancer therapy显示文摘 | McDonnell TJ Meyn RE Robertson LE | 1995 | Semin Cancer Biol1995，6，1： | 1 |
| 6 | Ensuring a knowledgeable and committed gerontological nursing work- force 显示文摘 | Plonczynski D J Jones LE Robertson JF | 2007 | Nurse Education Today2007，27，2： | 1 |
| 7 | Induction of apoptotic cell death in chronic lymphocytic leukemia by 2-chloro-2I -deoxyadenosine and 9-beta-D-arabinosyl- 2 显示文摘 | Robertson LE Chubb S Meyn RE | 1993 | Blood1993，81，1： | 1 |
| 8 | Richter's syndrome:a report on 39 patients显示文摘 | Robertson LE Pugh W O' Brien S | 1993 | J Clin Oncol1993，11，10： | 1 |
| 9 | Bacillus spore inactivation differences after combined mild temperature and gigh pressure processing using two pressurizing fluids显示文摘 | Robertson RE Carroll T Pearee LE | 2008 | J Food Prot2008，71，6： | 1 |
| 10 | Induction of Apoptotic cell Death in chronic lymphocytic leukemia by 2-2'-deoxydenosiue and 9-B-D-Arabinosy 1-2-fluoademine 显示文摘 | By LE Robertson Sherr Chubb Raymond E | 1993 | Blood1993，81，： | 1 |
| 11 | Human ureaplasmas show diverse genome sizes by pulse-field eleetrophoresis 显示文摘 | Robertson J A Pyle LE Stemke G W | 1990 | Nucleic Acids Res1990，18，6： | 1 |
| 12 | Richter's syndrome : a report on 39 patients显示文摘 | Robertson LE Pugh W O'Brien S | 1993 | J Clin Oncol1993，11，： | 1 |
| 13 | Implications of apoptotic cell death regulation in cancer therapy 显示文摘 | Mc Donnell TJ Meyn RE Robertson LE | 1995 | Semin Cancer Biol1995，6，1： | 1 |
| 14 | Survival outcomes and predictors of mortality,re-bleeding and complications for acute severe variceal bleeding requiring balloon tamponade显示文摘BACKGROUND Acute severe variceal bleeding(AVB)refractory to medical and endoscopic therapy is infrequent but associated with high mortality.Historical cohort studies from 1970-1980s no longer represent the current population as balloon tamponade is no longer first-line therapy for variceal bleeding;treatments including vasoactive therapies,intravenous antibiotics,endoscopic variceal band ligation are routinely used,and there is improved access to definitive treatments including transjugular intrahepatic portosystemic shunts.However,only a few studies from the current era exist to describe the practice of balloon tamponade,its outcomes,and predictors with a requirement for further updated information.AIM To describe current management of AVB requiring balloon tamponade and identify the outcomes and predictors of mortality,re-bleeding and complications.METHODS A retrospective multi-centre cohort study of 80 adult patients across two large tertiary health networks from 2008 to 2019 in Australia who underwent balloon tamponade using a Sengstaken-Blakemore tube(SBT)were included for analysis.Patients were identified using coding for balloon tamponade.The primary outcome of this study was all-cause mortality at 6 wk after the index AVB.Secondary outcomes included re-bleeding during hospitalisation and complications of balloon tamponade.Predictors of these outcomes were determined using univariate and multivariate binomial regression.RESULTS The all-cause mortality rates during admission and at 6-,26-and 52 wk were 48.8%,51.2%and 53.8%,respectively.Primary haemostasis was achieved in 91.3%and re-bleeding during hospitalisation occurred in 34.2%.Independent predictors of 6 wk mortality on multivariate analysis included the Model for Endstage Liver disease(MELD)score(OR 1.21,95%CI 1.06-1.41,P=0.006),advanced hepatocellular carcinoma(OR 11.51,95%CI 1.61-82.20,P=0.015)and re-bleeding(OR 13.06,95%CI 3.06-55.71,P<0.001).There were no relevant predictors of re-bleeding but a large proportion in which this occurred did not survive 6 wk(76.0%vs 24%).Although mucosal trauma was the most common documented complication after SBT insertion(89.5%),serious complications from SBT insertion were uncommon(6.3%)and included 1 patient who died from oesophageal perforation.CONCLUSION In refractory AVB,balloon tamponade salvage therapy is associated with high rates of primary haemostasis with low rates of serious complications.Re-bleeding and mortality however,remain high. | Charlotte Y Keung Aparna Morgan Suong T Le Marcus Robertson Paul Urquhart Michael P Swan | 2022 | World Journal of Hepatology2022，14，8： | 0 |
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