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17篇 您的检索式:作者名="Rogier B"
    题名 作者 年代 出处 被引量
1Characterization of Zireonia Films Deposited by RF Magnetron Sputtering 显示文摘Ben Amor S Rogier B Baud G 1998Materials Science and Engineering: B1998,7,1:1
2The role of cytotoxic drugs in the treatment of central nervous system gliomas 显示文摘Neyns B D'Haeseleer M Rogiers A 2010Acta Neurol Belg2010,110,1:1
3Electrophoretic analysis of genetic variability in a landlock striped bass population显示文摘Rogier C G Ney J J and Turner B J 1985Trans Am Fish Soc1985,114,:1
4Efficient posterior exploration of a high-dimensional groundwater model from two- stage M CMC simulation and polynomial chaos expansion 显示文摘Laloy E Rogiers B Vrugt J A 2013Water Resources Research2013,49,5:1
5Shrinkage of thyroid volume in Sunitinib-treated patientswith renal-cell carcino-ma:a potential marker of irreversible thyroid dysfunction 显示文摘Rogiers A Wolter P Opde B 2010Thyroid2010,20,3:1
6Development and valid- ation of a fast chromatographic method for screening and quantifi- cation of legal and illegal skin whitening agents显示文摘Desmedt B Rogiers V Courselle P 2013Journal of Pharmaceutical and Biomedical Analysis2013,83,:1
7The role of cytotoxic drugs in the treatment of central nervous system gliomas显示文摘Neyns B D'Haeseleer M Rogiers A 2010Acta Neurol Belg2010,110,1:1
8Efficient posterior exploration of a high-dimensional groundwater model from two-stage MCMC simulation and polynomial chaos expansion显示文摘LALOY E ROGIERS B VRUGT J A 2013Water Resources Research2013,49,5:1
9The role of cytotoxic drugs in the treatment of central nervous system gliomas 显示文摘Neyns B Dhaeseleer M Rogiers A 2010Acta Neurol Belg2010,110,1:1
10The role of cytotoxic drugs in the treatment of central nervous system gliomas显示文摘Neyns B D'Haeseleer M Rogiers A 2010Acta Neurol Belg2010,110,1:1
11Comparison of the effectiveness of trauma-focused cognitive behavioral therapy and paroxetine treatment in PTSD patients:Design of a randomized controlled trial显示文摘A Rosaura Polak Anke B Witteveen Rogier Visser 2012BMC Psychiatry2012,2,12:1
12Elerated factor Ⅷ levels and the risk of thrombsis显示文摘PIETER W K IEROEN C J E ROGIER M B 2001Arterioscler THnomb Vasc Biol2001,21,5:1
13Estimation of hydraulic conductivity and its uncertainty from grain- size data using GLUE and artificial neural networks 显示文摘B Rogiers D Mallants O Batelaan 2012Mathematical Geosciences2012,44,6:1
143,4-Diarylthiophenes are selective COX-2 inhibito显示文摘Stephen R B Talley J J Rogier D J 1995Bioorg Med Chem Lett1995,5,23:1
15Characterization of zirconia films deposited by RF magnetron sputtering显示文摘Ben A S Rogier B Baud G 1998Materials Science and Engineering= B1998,57,1:1
16Development and validation of a fast chromatographic method for screening and quantification of legal and illegal skin whitening agents显示文摘Desmedt B Rogiers V Courselle P 2013Journal of Pharmaceutical and Biomedical Analysis2013,83,:1
17MLC1在调节星形胶质细胞-突触相互作用中的新角色显示文摘星形胶质细胞膜蛋白MLC1的功能丧失是伴皮质下囊肿的巨脑性白质脑病(MLC)的主要遗传原因,这一罕见病的特征是脑内离子和水稳态失衡。MLC1蛋白主要分布于大脑中的液体屏障周围,例如在星形胶质细胞接触血管的终足和接触脑膜的突起中。该蛋白是否在其他星形胶质细胞结构域中发挥作用尚不清楚。本研究表明MLC1存在于星形胶质细胞远端突起中,也称为突触周围星形胶质细胞突起(PAP)或星形胶质细胞小叶;在海马CA1区域它们与兴奋性突触密切相互作用。我们发现在Mlc1缺失小鼠中,向兴奋性突触延伸的PAP末端缩短。这一改变会影响谷氨酸能突触传递,导致自发释放事件的速率降低,并在具有挑战性的条件下减慢谷氨酸的再摄取。此外,虽然野生型小鼠中的PAP在恐惧调节过程从突触回缩,但我们发现在Mlc1缺失小鼠中,这种结构可塑性在本已更短的PAP出现障碍。最后,Mlc1缺失小鼠显示情境恐惧记忆减少。总之,本研究揭示了星形胶质细胞蛋白MLC1在调节PAP结构方面的意想不到的作用。MLC1的缺失会改变兴奋性突触传递,阻止恐惧调节诱导的正常PAP重塑,并破坏情境恐惧记忆表达。因此,MLC1是调节星形胶质细胞-突触相互作用的新参与者。Mandy S J Kater Katharina F Baumgart Aina Badia-Soteras Tim S Heistek Karen E Carney A Jacob Timmerman Jan R T vanWeering August B Smit Marjo S van der Knaap Huibert D Mansvelder Mark H G Verheijen Rogier Min 2023神经损伤与功能重建2023,18,5:0
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