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10篇 您的检索式：作者名="Roland Zimmermann"

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		题名	作者	年代	出处	被引量
	1	Increased susceptibility for intrahepatic cholestasis of pregnancy and contraceptive-induced cholestasis in carriers of the 1331T>C polymorphism in the bile salt export pump显示文摘AIM: To study the association of three common ABCB11 and ABCC2 polymorphisms (ABCB11: 1331T>C V444A; ABCC2: 3563T>A V1188E and 4544G>A C1515Y) with intrahepatic cholestasis of pregnancy (ICP) and contraceptive-induced cholestasis (CIC). METHODS: ABCB11 and ABCC2 genotyping data were available from four CIC patients and from 42 and 33 ICP patients, respectively. Allele-frequencies of the studied polymorphisms were compared with those in healthy pregnant controls and Caucasian individuals. Furthermore, serum bile acid levels were correlated with the presence or absence of the 1331 C allele.RESULTS: The ABCB11 1331T>C polymorphism was significantly more frequent in cholestatic patients than in pregnant controls: C allele 76.2% (CI, 58.0-94.4) vs 51.3% (CI 35.8-66.7), respectively (P = 0.0007); and CC allele 57.1% (CI 36.0-78.3) vs 20% (CI 7.6-32.4), respectively (P = 0.0065). All four CIC patients were homozygous carriers of the C allele. In contrast, none of the studied ABCC2 polymorphism was overrepresented in ICP or CIC patients. Higher serum bile acid levels were found in carriers of the 1331CC genotype compared to carriers of the TT genotype.CONCLUSION: Our data support a role for the ABCB11 1331T>C polymorphism as a susceptibility factor for the ←←← development of estrogen-induced cholestasis, whereas no such association was found for ABCC2. Serum bile acid and γ-glutamyl transferase levels might help to distinguish ABCB4- and ABCB11-related forms of ICP and CIC.	Yvonne Meier Tina Zodan Carmen Lang Roland Zimmermann Gerd A Kullak-Ublick Peter J Meier Bruno Stieger Christiane Pauli-Magnus	2008	World Journal of Gastroenterology2008，14，1：	20
	2	Prolonged Salivary Cortisol Recovery in Second-Trimester Pregnant Women and Attenuated Salivary α-Amylase Responses to Psychosocial Stress in Human Pregnancy显示文摘	Ada Nierop Aliki Bratsikas Ariadne Klinkenberg Urs M. Nater Roland Zimmermann Ulrike Ehlert	2006	The Journal of Clinical Endocrinology & Metabolism2006，，4：	1
	3	Monte Carlo growth simulation for AlxGa1-xAs heteroepitaxy 显示文摘	Frank Grosse Roland Zimmermann	2000	Journal of Crystal Growth2000，212，12：	1
	4	Multipotent mesenchymal stem cells from human placenta: critical parameters for isolation and maintenance of stemness after isolation显示文摘	Oleg V. Semenov Sonja Koestenbauer Mariluce Riegel Nikolas Zech Roland Zimmermann Andreas H. Zisch Antoine Malek	2010	American Journal of Obstetrics and Gynecology2010，，2：	1
	5	Stress-buffering effects of psychosocial resources on physiological and psychological stress response in pregnant women显示文摘	Ada Nierop Petra H. Wirtz Aliki Bratsikas Roland Zimmermann Ulrike Ehlert	2008	Biological Psychology2008，，3：	1
	6	Folio acid:a public-health challenge显示文摘	Monika Eichholzer Otmar T?nz Roland Zimmermann	2006	Lancet2006，22，367：	1
	7	Highly efficient and straightforward functionalization of cel-lulose films with thiol-ene click chemistry显示文摘	TINGAUT Philippe HAUERT Roland ZIMMERMANN Tan-ja		0，，40：	1
	8	Correlation between middle cerebral artery peak systolic velocity and fetal hemoglobin after 2 previous intrauterine transfusions显示文摘	Giancarlo Mari Roland Zimmermann Kenneth J. Moise Russell L. Deter	2005	American Journal of Obstetrics and Gynecology2005，，3：	1
	9	Analysing Debris-Flow Impact Models, Based on a Small Scale Modelling Approach 显示文摘	Christian Scheidl Michael Chiari Roland Kaitna Matthias Mtillegger Alexander Krawtschuk Thomas Zimmermann Dirk Proske	2013	Surveys in Geophysics2013，34，：	1
	10	Multipotent mesenchymal stem cells from human placenta: critical parameters for isolation and maintenance of stemness after isolation显示文摘	Oleg V. Semenov Sonja Koestenbauer Mariluce Riegel Nikolas Zech Roland Zimmermann Andreas H. Zisch Antoine Malek	2010	American Journal of Obstetrics and Gynecology2010，，2：	1

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