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| 1 | Pyogenic liver abscess:An audit of 10 years’experience显示文摘AIM:To describe our own experience with pyogenic liver abscesses over the past 10 years and investigate the risk factors associated with failure of initial percutaneous therapy.METHODS:A retrospective study of records of 63 PLA patients presenting between 1998 and 2008 to Australian tertiary referral centre,were reviewed.Amoebic and hydatid abscesses were excluded.Demographic,clinical,radiological,and microbiological characteristics,as well as surgical/radiological interventions,were recorded.RESULTS:Sixty-three patients(42 males,21 females) aged 65(±14) years[mean±(SD) ]had prodromal symptoms for a median(interquartile range;IQR) of 7(5-14) d.Only 59%of patients were febrile at presentation;however,the serum C-reactive protein was elevated in all 47 in whom it was measured.Liver function tests were non-specifically abnormal.67%of patients had a solitary abscess,while 32%had>3 abscesses with a median(IQR) diameter of 6.3(4-9) cm.Causative organisms were:Streptococcus milleri 25%,Klebsiella pneumoniae 21%,and Escherichia coli 16%.A presumptive cryptogenic cause was most common (34%).Four patients died in this series:one from sepsis,two from advanced cancer,and one from acute myocardial infarction.The initial procedure was radiological aspiration±drainage in 54 and surgery in two patients.17%underwent surgical management during their hospitalization.Serum hypoalbuminaemia[mean (95%CI) :32(29-35) g/L vs 28(25-31) g/L,P=0.045] on presentation was found to be the only factor related to failure of initial percutaneous therapy on univariate analysis.CONCLUSION:PLA is a diagnostic challenge,because the presentation of this condition is non-specific.Intravenous antibiotics and radiological drainage in the first instance allows resolution of most PLAs;However,a small proportion of patients still require surgical drainage. | Tony CY Pang Thomas Fung Jaswinder Samra Thomas J Hugh Ross C Smith | 2011 | World Journal of Gastroenterology2011，17，12： | 46 |
| 2 | Templated self-assembly of block copolymers:Top-down helps bottom-up显示文摘 | Cheng J Ross C Smith H | | 0，，19： | 1 |
| 3 | SCAMP: measuring turbulence in estuaries, lakes, and coastal waters 显示文摘 | STEVENS C SMITH M ROSS A | 1999 | NIWA-Waterand Atmosphere1999，7，2： | 1 |
| 4 | Feed-forward regula- tion of gibberellln deactivation in pea显示文摘 | Elliott R C Ross J J Smith J J | 2001 | J Plant Growth Regul2001，20，： | 1 |
| 5 | The OBO foundry: Coordinated evolution of ontologies to Support biomedical data integration显示文摘 | Smith B Ashburner M Rosse C | 2007 | Nature Bio technology2007，25，： | 1 |
| 6 | Fabrication of patterned media for high density magnetic storage显示文摘 | Ross C A Smith Henry I Savas T | 1999 | J Vac Sci Technol B1999，17，3： | 1 |
| 7 | Fabrication ofpat- terned media for high density magnetic storage显示文摘 | Ross C A Smith H I Savas T | 1999 | J Vac Sei Technol1999，17，6： | 1 |
| 8 | Yield management at American alrlines显示文摘 | Smith C John F Ross M | | 0，，01： | 1 |
| 9 | Yield Management at American Airlines显示文摘 | Barry C Smith F Leimkuhler Ross M Darrow | 1991 | Interface1991，22，1： | 1 |
| 10 | Templated self-assembly of block copolymers: top-down helps bottom-Up显示文摘 | CHENG J Y ROSS C A SMITH H I | 2006 | Adv mater2006，18，： | 1 |
| 11 | Templated self-as- sembly of block copolymers: Top-down helps bottom-up 显示文摘 | Cheng J Y Ross C A Smith H I | 2006 | Adv Mater2006，18，19： | 1 |
| 12 | Baicalein reduces e46k alpha-synuclein aggregation in vitro and protects cells against e46k alpha-synuclein toxicity in cell models of familiar parkinsonism显示文摘 | Jiang M Porat-Shliom Y Pei Z Cheng Y Xiang L Sommers K Li Q Gillardon F Hengerer B Berlinicke C Smith WW Zack DJ Poirier MA Ross CA DuanW | | 0，，： | 1 |
| 13 | Templated self-assembly of block copolymers:top-down helpsbottom-Up显示文摘 | CHENG J Y ROSS C A SMITH H I | | 0，，： | 1 |
| 14 | Templated selfassembly of block copolymers: Top-down helps bottom-up显示文摘 | Cheng J Y Ross C A Smith H I | | Adv Mater0，18，19： | 1 |
| 15 | The OBO foundry:coordinated evolution of ontologies to support biomedical data integration显示文摘 | SMITH B ASHBURNER M ROSSE C | 2007 | Nature Biotechnology2007，25，11： | 1 |
| 16 | Templated self-assembly of block copolymers:Top-down helps bottom-up显示文摘 | Cheng J Y Ross C A Smith H I | 2006 | Advanced Materials2006，18，19： | 1 |
| 17 | Evidence that auxin promotes gibberellin AI biosynthesis in pea显示文摘 | Ross J J O'Neill D P Smith J J Kerckhoffs L H J Elliott R C | 2000 | The Plant Journal2000，21，： | 1 |
| 18 | The OBOFoundry: coordinated evolution of ontologies to supportbiomedical data integration显示文摘 | SMITH B ASHBURNER M ROSSE C | 2007 | Nature Biotechnology2007，25，11： | 1 |
| 19 | Templated self-assembly of block copolymers: Top-down helps bottom-up 显示文摘 | Cheng J Y Ross C A Smith H I | | Adv Mater0，18，19： | 1 |
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