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| 1 | Fecal microbiota transplantation as novel therapy in gastroenterology:A systematic review显示文摘AIM:To study the clinical efficacy and safety of Fecal microbiota transplantation(FMT).We systematically reviewed FMT used as clinical therapy.METHODS:We searched MEDLINE,EMBASE,the Cochrane Library and Conference proceedings from inception to July,2013.Treatment effect of FMT was calculated as the percentage of patients who achieved clinical improvement per patient category,on an intention-to-treat basis.RESULTS:We included 45 studies;34 on Clostridium difficile-infection(CDI),7 on inflammatory bowel disease,1 on metabolic syndrome,1 on constipation,1 on pouchitis and 1 on irritable bowel syndrome(IBS).In CDI 90% resolution of diarrhea in 33 case series(n = 867) was reported,and 94% resolution of diarrhea after repeated FMT in a randomized controlled trial(RCT)(n = 16).In ulcerative colitis(UC) remission rates of 0% to 68% were found(n = 106).In Crohn's disease(CD)(n = 6),no benefit was observed.In IBS,70% improvement of symptoms was found(n = 13).100% Reversal of symptoms was observed in constipation(n = 3).In pouchitis,none of the patients(n = 8) achieved remission.One RCT showed significant improvement of insulin sensitivity in metabolic syndrome(n = 10).Serious adverse events were rare.CONCLUSION:FMT is highly effective in CDI,and holds promise in UC.As for CD,chronic constipation,pouchitis and IBS data are too limited to draw conclusions.FMT increases insulin sensitivity in metabolic syndrome. | Noortje G Rossen John K Mac Donald Elisabeth M de Vries Geert R D'Haens Willem M de Vos Erwin G Zoetendal Cyriel Y Ponsioen | 2015 | World Journal of Gastroenterology2015，21，17： | 41 |
| 2 | 颈淋巴结清扫术对分化型甲状腺癌患者生活质量的影响显示文摘颈部淋巴结转移在分化型甲状腺癌(DTC)中十分常见。DTC患者整体长期生存率高于90%。尽管DTC具有良好的预后,但因淋巴结转移而造成局部复发者增加,将降低患者的生活质量,影响患者的预后。因此,对患者的关注从以整体存活率为重点转变为以最近提出的无复发生存率为重点。为了这一目标,适当的淋巴结清扫是非常重要的。这种手术策略将阻止疾病的复发,但有增加并发症的可能。传统上,对肿瘤患者的评估主要是基于术后生存率,但近来认识到,在癌症的诊断与管理过程中,可以对患者的生活质量的各个方面产生重大影响。癌症的治疗目的,不仅仅是提高生存率,也应该保证患者的生活质量,同时评估这些变化也变得十分重要。 | Rossen S.Dimov 冯铁成 李新营 | 2014 | 中国普通外科杂志2014，23，5： | 5 |
| 3 | Abnormalities of masseter inhibitory reflex in patients with episodic tension-type headache显示文摘调查妈 seter 的目的禁止的反射(米尔) 和它在有阵发性的紧张类型头疼(TTH ) 的病人的最终的变化。方法米尔与阵发性的 TTH 和 30 个健康题目在 21 个病人被学习,与匹配到学习队的年龄和性别。病人的中部的年龄是 17.0 年(变化 16 ∼49 年) ,疾病 12 月(1 ∼5 年) 的中部的持续时间,和头疼 7.5 d 的中部的频率每月。结果米尔的抑制(S2 ) 的第二个时期在 10% 控制和 66.7% 在紧张和持续时间被减少(信心间隔(CI )=45.3%∼85% ;P<0.05 ) 有阵发性的 TTH 的病人(χ2=74.9;P<0.001 ) 。(14.3%) 在 3,有阵发性的 TTH 的病人,, S2 是完全不在的。在疾病和头疼频率的持续时间之间的重要关联都没被发现。我们的结果证实在 S2 的阵发性的 TTH 和减小或缺席之间的连接的结论。有阵发性的 TTH 的十几岁的病人可以与更老的个人相对照在 S2 展出显著病理学的变化。 | Plamen TZVETANOV Rossen Todoroff ROUSSEFF Zdravka RADIONOVA | 2009 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2009，10，1： | 5 |
| 4 | Modeling flow in naturally fractured reservoirs: effect of fracture aperture distribution on dominant sub-network for flow显示文摘Fracture network connectivity and aperture(or conductivity) distribution are two crucial features controlling flow behavior of naturally fractured reservoirs. The effect of connectivity on flow properties is well documented. In this paper, however, we focus here on the influence of fracture aperture distribution. We model a twodimensional fractured reservoir in which the matrix is impermeable and the fractures are well connected. The fractures obey a power-law length distribution, as observed in natural fracture networks. For the aperture distribution,since the information from subsurface fracture networks is limited, we test a number of cases: log-normal distributions(from narrow to broad), power-law distributions(from narrow to broad), and one case where the aperture is proportional to the fracture length. We find that even a wellconnected fracture network can behave like a much sparser network when the aperture distribution is broad enough(ɑ≤ 2 for power-law aperture distributions and σ≥ 0.4for log-normal aperture distributions). Specifically, most fractures can be eliminated leaving the remaining dominant sub-network with 90% of the permeability of the original fracture network. We determine how broad the aperture distribution must be to approach this behavior and the dependence of the dominant sub-network on the parameters of the aperture distribution. We also explore whether one can identify the dominant sub-network without doing flow calculations. | J. Gong W. R. Rossen | 2017 | Petroleum Science2017，14，1： | 5 |
| 5 | Giant saphenous vein graft pseudoaneurysm to right posterior descending artery presenting with superior vena cava syndrome显示文摘Saphenous vein grafts(SVG) pseudoaneurysms,especially giant ones,are rare and occur as a late complication of coronary artery bypass grafting. This condition affects both genders and typically occurs within the sixth decade of life. The clinical presentation ranges from an asymptomatic incidental finding on imaging studies to new onset angina,dyspnea,myocardial infarction or symptoms related to compression of neighboring structures. An 82-year-old woman presented with acute onset back pain,dyspnea and was noted to have significantly engorged neck veins. In the emergency department,a chest computed tomographic angiogram with intravenous contrast revealed a ruptured giant bilobed SVG pseudoaneurysm to the right posterior descending artery(RPDA). This imaging modality also demonstrated compression of the superior vena cava(SVC) by the SVG pseudoaneurysm. Coronary angiogram with bypass study was performed to establish the patency of this graft. Endovascular coiling and embolization of the SVG to RPDA was initially considered but disfavored after the coronary angiogram revealed preserved flow from the graft to this arterial branch. After reviewing the angiogram films,a surgical strategy was favored over a percutaneous intervention with a Nitinol self-expanding stent since the latter would have not addressed the superior vena cava compression caused by the giant pseudoaneurysm. Intraoperative transesophageal echocardiogram demonstrated SVCcompression by the giant pseudoaneurysm cranial lobe. Our patient underwent surgical ligation and excision of the giant pseudoaneurysm and the RPDA was regrafted successfully. In summary,saphenous vein grafts pseudoaneurysms can be life-threatening and its therapy should be guided based on the presence of mechanical complications,the patency of the affected vein graft and the involved myocardial territory viability. | Andres Vargas-Estrada Dianna Edwards Mohammad Bashir James Rossen Firas Zahr | 2015 | World Journal of Cardiology2015，7，6： | 3 |
| 6 | Reduction of Peritoneal Trauma By Using Nonsurgical Gauze Leads to Less Implantation Metastasis of Spilled Tumor Cells显示文摘 | Petrousjka M. van den Tol Elma E. M. van Rossen Casper H. J. van Eijck Fred Bonthuis Richard L. Marquet Hans Jeekel | 1998 | Annals of Surgery1998，，2： | 2 |
| 7 | Nephrogenic systemic fibrosis: suspected causative role of gadodiamide used for contrast-enhanced magnetic resonance imaging 显示文摘 | Marckmann P Skov L Rossen K | 2006 | J Am Soc Nephrol2006，17，： | 1 |
| 8 | Cellular basis for the negative inotropic effects of tumor necrosis factor-a in the adult mammalian cardiac myocyte 显示文摘 | Vaca RD Rossen W | 1993 | J Clin invest1993，92，： | 1 |
| 9 | Cellar basis for the megative inotropie effects of tumor necrosis factor-α in the adult mammalian heart 显示文摘 | Yokoyama T Vaca L Rossen R D | 1993 | J Clin Invest1993，92，： | 1 |
| 10 | Inhibition of PCRby components of food samples,microbial diagnostic assays and DNA-extraction solutions显示文摘 | ROSSEN L NORSKOV P HOLMSTROM K | 1992 | Int J Food Microbiol1992，17，1： | 1 |
| 11 | Functional Central Limit Theorem approximations and the distribution of the Dickey-Fuller test with strongly heteroskedastic data显示文摘 | Rossen V | 2005 | Economics letters2005，86，： | 1 |
| 12 | Associa- tions between pathogens in the upper respiratory tract of young children:interplay between viruses and bacteria显示文摘 | van den Bergh MR Biesbroek G Rossen JW | 2012 | PLoS One2012，7，47： | 1 |
| 13 | Diagnostic value of real-time polymerase chain reaction to detect viruses in young children admitted to the paediatric intensive care unit with lower respiratory tract infection 显示文摘 | van de Pol AC Wolfs TF Jansen N J van Loon AM Rossen JW | 2006 | Crit Care2006，10，2： | 1 |
| 14 | Nucleocapsid-independent assembly of coronavirus- like particles by co-expression of virus envelope pro- teingenes显示文摘 | VENNEMA H GODEKE G J ROSSEN J W | 1996 | EMBOJ1996，15，8： | 1 |
| 15 | Cement substitution by a combi- nation of metakaolin and limestone显示文摘 | Antoni M Rossen J Martirena F | 2012 | Cement and Concrete Research2012，42，12： | 1 |
| 16 | Synthesis and clectrochemical studies of LiMnO2 prepared at low temperatures 显示文摘 | REIMERS J N FULLER E C ROSSEN E | 1993 | J Electrochem Soe1993，140，： | 1 |
| 17 | Structure and electrochemistry of Lix Fey Ni1 - y02 显示文摘 | J N Reimers E Rossen C D Jones | 1993 | Solid State lonics1993，61，4： | 1 |
| 18 | Media as a teaching tool in psy- chiatric nursing education显示文摘 | Wall B M Rossen E K | 2004 | Nurs Educ2004，29，1： | 1 |
| 19 | Inhibition of PCR by components of food samples,microbial diagnostic assays and DNA-extraction solutions显示文摘 | Rossen L Nrskov P Holmstrm K | 1992 | Int J Food Microbiol1992，17，1： | 1 |
| 20 | MIDAS Regressions: Further Results and New Directions显示文摘 | Eric Ghysels Arthur Sinko Rossen Valkanov | 2007 | Econometric Reviews2007，，1： | 1 |
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