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| 1 | Age distribution,polyps and rectal cancer in the Egyptian population-based cancer registry显示文摘AIM:To describe the clinical and epidemiologic profiles of the disease and to compare the findings with those generated from the previous hospital-based studies.METHODS:The Gharbiah cancer registry is the only population-based cancer registry in Egypt since 1998.We analyzed the data of all colorectal cancer patients included in the registry for the period of 1999-2007.All medical records of the 1364 patients diagnosed in Gharbiah during the study period were retrieved and the following information abstracted:age,residence,diagnosis date,grade,stage,topology,clinical characteristics,and histology variables.Egyptian census data for 1996 and 2006 were used to provide the general population's statistics on age,sex,residence and other related demographic factors.In addition to age-and sex-specific incidence rate analyses,we analyze the data to explore the incidence distribution by rural-urban differences among the 8 districts of the province.We also compared the incidence rates of Gharbiah to the rates of the Surveillance Epidemiology and End Results(SEER) data of the United States.RESULTS:Over the 9 year-period,1364 colorectal cancer cases were included.The disease incidence under age 40 years was relatively high(1.3/10 5) while the incidence in the age groups 40 and over was very low(12.0/10 5,19.4/10 5 and 21.2/10 5 in the age groups 40-59 years,60-69 years and > 70 years,respectively).The vast majority of tumors(97.2%) had no polyps and 37.2% of the patients presented with primary lesions in the rectum.Colorectal cancer was more common in patients from urban(55%) than rural(45%) areas.Regional differences in colon and rectal cancer incidence in the 8 districts of the study province may reflect different etiologic patterns in this population.The registry data of Egypt shows a slightly higher incidence of colorectal cancer than the United States in subjects under age 40 years.The results also shows significantly lower incidence of colorectal cancer in subjects over age 40 years compared to the same age group in the United States SEER.CONCLUSION:Low rate of polyps,low incidence in older subjects,and high rate of rectal cancer in Egypt.Future studies should explore clinical and molecular disease patterns. | Darlene Veruttipong Amr S Soliman Samuel F Gilbert Taylor S Blachley Ahmed Hablas Mohamed Ramadan Laura S Rozek Ibrahim A Seifeldin | 2012 | World Journal of Gastroenterology2012，18，30： | 12 |
| 2 | Benefits and Costs of Intellectual Property Protection in Developing Countries 显示文摘 | Rapp Rozek | 1990 | Journal of World Trade1990，7577，： | 1 |
| 3 | An approach to membranefouling characterization by confocal scanning laser microscopy显示文摘 | Ferrando M Rozek A Zator M | 2005 | Journal of Membrane Science2005，250，12： | 1 |
| 4 | Daptomycin structure and mechanism of action revealed显示文摘 | Jung D Rozek A Okon M | | 0，，： | 1 |
| 5 | Benefits and Costs of Intellectual Proper- ty Protection in Developing Countries显示文摘 | Rapp R T Rozek R P | 1990 | Journal of World Trade1990，24，5： | 1 |
| 6 | Sequestosome-1/p62 is the key intracellular target of innate defense regulator peptide显示文摘 | Vu HB Kielczewska A Rozek A | 2009 | J Biol Chem2009，284，36： | 1 |
| 7 | Role of membranes in the activities of antimicrobial cationic peptides显示文摘 | Hancock R E Rozek A | 2002 | FEMS Mi- crobiology Letters2002，206，： | 1 |
| 8 | Benefits and costs of intellectual property protection in developing countries显示文摘 | Rapp Richard T Rozek Richard P | 1990 | Journal ot World Trade1990，24，5： | 1 |
| 9 | Adverse effects of Wolff-Parkinson-White syndrome with right septal or posteroseptal accessory pathways on cardiac function 显示文摘 | Tomaske M Janousek J ROzek V' | 2008 | Europace2008，10，18： | 1 |
| 10 | Benefits and costs of intel- lectual property protection in developing countries 显示文摘 | RAPP RICHARD RICHARD P ROZEK | 1990 | Journal of world trade1990，，77： | 1 |
| 11 | Role of membranes in the activities of antimicrobial cationic peptides显示文摘 | Hancock R E Rozek A | 2002 | FEMS Microbiol Lett2002，206，2： | 1 |
| 12 | Interaction and cellular localization of the human host defense peptide LL-37 with lung epithelial cells显示文摘 | Lau Y E Rozek A Scott M G | 2005 | Infect Immun2005，73，： | 1 |
| 13 | Patterns of cellular and HPV 16 methylation as biomarkers for cervical neoplasia显示文摘 | Patel D A Rozek L S Colacino J A | | 0，，1： | 1 |
| 14 | Benefits and costs of intellectual property protection in developing countries显示文摘 | RAPP R T ROZEK R P | 1990 | Journal of World Trade1990，，24： | 1 |
| 15 | Paraoxonase(PON1)phenotype is a better predictor of vascular disease than is PON1(192)or PON1(55)genotype显示文摘 | Jarvik GP Rozek LS Brophy VH | 2000 | Arterioscler Thromb Vasc Biol2000，20，11： | 1 |
| 16 | Structure-Based design of an indolicidin peptide analogue with increased proteasestability显示文摘 | ROZEK A POWERS J S FRIEDRICH C L | 2003 | Biochemistry2003，42，14： | 1 |
| 17 | Benefits and costs of intellectual property protection in developing countries 显示文摘 | Rapp R Rozek R | 1990 | Journal of World Trade1990，，24： | 1 |
| 18 | External fixation in thetreatment of severe tibial fractures complicated by soft tissue injury 显示文摘 | Sluzalek M Gazdzik T S M rozek S | 2004 | Ortop traumatol Rehabil2004，6，1： | 1 |
| 19 | Telepathology and the networking of pathology diagnostic services 显示文摘 | Weinstein RS Bloom K J Rozek LS | 1987 | Arch pathol Lab Med1987，111，7： | 1 |
| 20 | Interaction of cationic antimicrobial peptides with model membranes显示文摘 | Zhang L J Rozek A Robert E W | 2001 | Biol Chem2001，276，35： | 1 |
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