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| 1 | Genomic and genetic alterations influence the progression of gastric cancer显示文摘Gastric cancer is one of the leading causes of cancerrelated deaths worldwide, although the incidence has gradually decreased in many Western countries. Two main gastric cancer histotypes, intestinal and diffuse, are recognised. Although most of the described genetic alterations have been observed in both types, different genetic pathways have been hypothesized. Genetic and epigenetic events, including 1q loss of heterozygosity (LOH), microsatellite instability and hypermethylation, have mostly been reported in intestinal-type gastric carcinoma and its precursor lesions, whereas 17p LOH, mutation or loss of E-cadherin are more often implicated in the development of diffuse-type gastric cancer.In this review, we summarize the sometimes contradictory findings regarding those markers which influence the progression of gastric adenocarcinoma. | Stefania Nobili Lorenzo Bruno Ida Landini Cristina Napoli Paolo Bechi Francesco Tonelli Carlos A Rubio Enrico Mini Gabriella Nesi | 2011 | World Journal of Gastroenterology2011，17，3： | 17 |
| 2 | 血管紧张素转换酶抑制剂和血管紧张素受体拮抗剂的使用与2019冠状病毒疾病检测阳性之间的关系显示文摘血管紧张素转换酶抑制剂(angiotensin-converting enzyme inhibitor,ACEI)和血管紧张素受体拮抗剂(angiotensin receptor blocker,ARB)在2019新型冠状病毒疾病(coronavirus disease 2019,COVID-19)全球大流行背景下的作用备受争议。此类药物是治疗一些慢性病的必须药物,有建议停止使用这些药物. | Mehta N KalraA Nowacki AS Anjewierden S Han Z Bhat p Rubio AEC Jacob M Procop GW Harrington S Milinovich A Svensson LG Jehi L Young JB Chung MK 周卫(译) 叶鹏(校) | 2020 | 中华高血压杂志2020，28，5： | 9 |
| 3 | Serrated adenoma of the stomach:Case report and literature review显示文摘Gastric serrated adenomas are histologically characterized by protruding glands with lateral saw tooth-like indentations lined with stratified dysplastic cells containing abundant eosinophilic cytoplasm.Since the first case of gastric serrated adenoma found in 2001,18 additional cases have been reported.Gastric serrated adenomas have a particular proclivity to progress to invasive carcinoma;75% or 15 of the 20 cases now in record-including the present one-exhibited invasive carcinoma.The 20 th case of gastric serrated adenoma reported here differs from the preceding ones in as much as it evolved in a patient with Lynch syndrome,implying that this adenoma phenotype may develop not only sporadically but also in patients with hereditary traits. | Carlos A Rubio Jan Bjrk | 2013 | World Journal of Gastrointestinal Endoscopy2013，5，5： | 4 |
| 4 | Germanene: a novel two-dimensional germanium allotrope akin to graphene and silicene显示文摘 | M E Dávila L Xian S Cahangirov A Rubio G Le Lay | 2014 | New Journal of Physics2014，，： | 3 |
| 5 | Low cost adsorbents for low temperature cleaning of flue gases显示文摘 | Bego?a Rubio María Teresa Izquierdo | 1998 | Fuel1998，，6： | 2 |
| 6 | Android fat ditribution as predictor of severity in acute pancreatitis 显示文摘 | Mery CM Rubio V Duarte - Rojo A | 2002 | Pancreatology2002，2，6： | 1 |
| 7 | Improved charge transfer at carbon nanotube electrodes显示文摘 | Britto P J Santhanam KSV Rubio A | 1999 | Adv Mater1999，，11： | 1 |
| 8 | Use of a certified reference material for extractable trace metals to assess source of uncertain in the BCR three-stage sequential extraction procedure显示文摘 | Sahuquillo A López-Sánchez J F Rubio R | 1999 | Anal Chim Acta1999，382，3： | 1 |
| 9 | Delineation of thyroid hormone-responsive sequences within a critical enhancer in the rat uncoupling protein gene显示文摘 | RABELO R SCHIFMAN A RUBIO A | 1995 | Endocrinology1995，136，3： | 1 |
| 10 | Hemimicelles of alkyl carboxylates chemisorbed onto magnetic nanoparticles: study and application to the extraction of carcinogenic polycyclic aromatic hydrocarbons in environmental water samples 显示文摘 | Ballesteros - Gomez A Rubio S | 2009 | Anal Chem2009，81，： | 1 |
| 11 | Hemangioblastoma of the optic nerve 显示文摘 | Rubio A Meyers SP Power JM | 1994 | Hum Pathol1994，25，11： | 1 |
| 12 | Cramer-Rao bound analysis of positioning approaches in the GNSS receivers显示文摘 | Closas P Fernandez-Prades C Fernandez'Rubio J A | 2009 | IEEE Transactions on Signal Pro- cessing2009，57，10： | 1 |
| 13 | Characterization and environmental application of a Chilean natural zeolite 显示文摘 | ENGLERT A H RUBIO J | 2005 | International Journal of Mineral Processing2005，75，12： | 1 |
| 14 | Radiation characteristics of thin-wire ternary fractal trees 显示文摘 | Werner D H Rubio B A Long B R | 1996 | Electronics Letters1996，35，8： | 1 |
| 15 | Effects of mammillary body lesions on spatial reference and working memory tasks显示文摘 | Santin LJ Rubio S Begega A | 1999 | Behav Brain Res1999，102，12： | 1 |
| 16 | In vitro reconstitution of an abscisic acid signalling pathway显示文摘 | FUJII H CHINNUSAMY V RODRIGUES A RUBIO S AATONI R PARK S Y CUTLER S R SHEEN J ROTRIGUES P L ZHU J K | 2009 | Nature2009，462，： | 1 |
| 17 | Antioxidant compounds in green and red peppers as affected by irrigation frequency,salinity and nutrient solution composition显示文摘 | Marín A Rubio J S Martínez V | 2009 | Journal of the Science of Food and Agriculture2009，89，： | 1 |
| 18 | Molecular characterization of the inactive allele of the gene GIu-A1 and the development of a set of AS-PCR markers for HMW glutenin of wheat显示文摘 | Bustos A De Rubio P Jouve N | 2000 | Theor Appl Genet2000，100，： | 1 |
| 19 | New basis for selective flocculation of mineral slimes 显示文摘 | RUBIO J MARABINI A M | 1977 | Trans Inst Min Metall1977，86，： | 1 |
| 20 | Nitric oxide, an iceberg in cardiovascular physiology : far beyond vessel tone control 显示文摘 | RUBIO A R MORALES SEGUM M A | 2004 | Arch Med Res2004，35，1： | 1 |
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