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| 1 | Cloning of first abc transporter encoding gene from Trichoderma spp. and its expression during stress and mycoparasitism显示文摘Trichoderma in its natural environment competes for nutrient uptake and is required to protect itself from adverse natural toxic compounds, such as those produced by plants and other microbes in the soil community, or synthetic toxic compounds released human activity. One of the most important metabolic pathways for drug resistance and substrate uptake, both in prokaryotes and eukaryotes, is ATP dependent. The role of ABC transporter proteins in the biology of Trichoderma is still not known. We present the cloning of the first four ABC transporter genes (TABC1, TABC2, TABC3, TABC4 ) in Trichoderma, and in particular T. atroviride P1, and the characterization of TABC2 The complete sequence of this gene is 6535 bp, which includes a promoter of 1624 bp, a terminator of 642 bp and a coding region of 4264 bp. The promoter contains many of the potential transcription factor binding sites found in the 5’ upstream region of the ech42 gene of T. atroviride P1. These included: heat shock factors (HSF), a nitrogen-regulating factor (Nit-2), a stress-response element (STRE), a GCR1 elements, and a Cre BP1 motif. Northern analysis and RT-PCR demonstrated that TABC2 is highly expressed when Trichoderma is subjected to nitrogen starvation, grown in the presence of culture filtrates of Botrytis cinerea, Rhizoctonia solani, and Pythium ultimum, or when N-acetylglucosamine is added to the substrate. TABC2 appears to be co-regulated with some CWDE-encoding genes, suggesting that this is the first ABC transporter encoding gene involved in mycoparasitic events. It’s role in the interaction of Trichoderma with fungal hosts or plants is being investigated by targeted gene disruption and overexpression. | Lanzuise S Ruocco M Scala V Catapano L Woo S Ciliento R Ferraioli S Soriente I Vinale F Scala F Del Sorbo G Lorito M | 2004 | 浙江大学学报(农业与生命科学版)2004，30，4： | 2 |
| 2 | The predictive value of plasma biomarkers in discharged heart failure patients:the role of plasma BNP显示文摘 | Beltrami M Palazzuoli A Ruocco G | 2016 | Minerva Cardioangiol2016，64，： | 1 |
| 3 | Dermoscopy of pigmented skin lesions (part Ⅱ) 显示文摘 | Soyer H P Argenziano G Ruocco V | 2001 | Eur J Dermatol2001，11，5： | 1 |
| 4 | P- atients with cardiorenal syndrome revealed increased neu- rohormonal activity, tubular and myocardial damage com- pared to heart failure patients with preserved renal function 显示文摘 | PALAZZUOLI A RUOCCO G PELLEGRINI M | 2014 | Cardiorenal Med2014，4，34： | 1 |
| 5 | Im- munological and clinical aspects of lymphocytic hypophys- itis显示文摘 | DE BELLIS A RUOCCO G BATTAGLIA M | 2008 | ClinSci (Lond)2008，114，6： | 1 |
| 6 | A case - contr ol study显示文摘 | POSTIGLIONE A MILAN G RUOCCO A Plasma folate vitamin B12 and total homocysteine and homozygosity for the C677T mutation of the 5 102 methylene tetrahydr ofolate reduetase gene in patientswithAlzheimer' s dementia | 2001 | Gerontology2001，47，： | 1 |
| 7 | Comparison of neutrophil gelatinase- associated li pocalin versus B- type natriuretic peptide and cystatin C to predict early acute kidney injury and outcome in patients with acute heart failure 显示文摘 | Palazzuoli A Ruocco G Pellegrini M | 2015 | Am J Cardiol2015，116，1： | 1 |
| 8 | Chronic kidney disease and worsening renal function in acute heart failure:different phenotypes with similar prognostic impact?显示文摘 | Palazzuoli A Lombardi C Ruocco G | 2015 | European Heart Journal Acute Cardiovascular Care2015，，9： | 1 |
| 9 | The super-grating:how to improve the limiting resolution of grating spectrometers显示文摘 | MAZZACURATI V RUOCCO G | 1990 | Optics Communications1990，76，34： | 1 |
| 10 | Pyoderma Pangrenosum : a review 显示文摘 | Ruocco E Sangiuliano S Gravina A G | 2009 | J Eur A cad Dermatol Venereol2009，23，9： | 1 |
| 11 | Analysis of a ther- moelectrical device for active heat transfer control 显示文摘 | MARUYAMA S NINO E RUOCCO G | 2001 | In- ternational Journal of Thermal Sciences2001，40，10： | 1 |
| 12 | 查看详情显示文摘 | Conti C Fratalocchi A Peccianti M Ruocco G Trillo S | | 0，，： | 1 |
| 13 | Pemphigus and bullous pemphigoid due to drugs显示文摘 | Ruocco V Sacerdoti G | 1991 | Int J Dermatol1991，30，5： | 1 |
| 14 | T helper 9 cells induced by plasmacytoid dendritic cells regulate interleukin-17 in multiple sclerosis显示文摘 | Ruocco G Rossi S Motta C | 2015 | Clin Sci2015，129，4： | 1 |
| 15 | 查看详情显示文摘 | Ghofraniha N Conti C Ruocco G Trillo S | | 0，，： | 1 |
| 16 | The role of natriuretic peptides for the diagnosis of left ventricular dysfunction 显示文摘 | Palazzuoli A Beltrami M Ruocco G | 2013 | ScientificWorldJournal2013，2013，78： | 1 |
| 17 | Regulatory T-cells in pregnancy: historical perspective, state of the art, and burning questions显示文摘 | Ruocco MG Chaouat G Florez L | 2014 | Front Immunoi2014，5，： | 1 |
| 18 | Combined microwavesand convection heating:A conjugate approach 显示文摘 | Marra F Bonis MVD Ruocco G | 2010 | FoodEng2010，97，： | 1 |
| 19 | Dopamine phenotype and behaviour in animal models:in relation to attention deficit hyperactivity disorder 显示文摘 | VIGGIANO D RUOCCO L A SADILE A G | 2003 | Neuroscience and Biobehavioral Reviews2003，27，7： | 1 |
| 20 | Saddles in the energy landscape probed by supercooled liquids显示文摘 | Angelani L Leonardo R Ruocco G | | 0，，： | 1 |
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