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| 1 | Performance-enhanced and cost-effective triboelectric nanogenerator based on stretchable electrode for wearable SpO2 monitoring显示文摘Recently,stretchable and wearable health monitoring equipment has greatly improved human’s daily life,which sets higher demands for portable power source in stretchability,sustainability,and biocompatibility.In this work,we proposed a stretchable triboelectric nanogenerator(TENG)based on stretchable poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate)(PEDOT:PSS)/porous carbon hybrid for oxyhemoglobin saturation(SpO2)monitoring.To combine advantages of carbon material for its high conductivity and organic electrode for its high stretchability,we spin-coated a solution of PEDOT:PSS/porous carbon onto a plasma-treated pre-stretched Ecoflex film to fabricate a stretchable electrode with rough surface.Due to its roughness and high potential difference with the dielectric material,the stretchable-electrode-based TENG exhibited better performance compared to the pristine TENG based on carbon or PEDOT:PSS material.The output voltage and current reached up to 51.5 V and 13.2μA as the carbon concentration increased.More importantly,the performance further increased under large strain(100%)which is suitable for wearable systems.Finally,the device demonstrated its application potential for powering a flexible blood oxygen monitor.This simple and cost-effective method can enhance the stretchability and stability of organic/inorganic electrode-based TENG,which paves the development of high-performance stretchable TENG. | Huamin Chen Wei Yang Cheng Zhang Mingqiang Wu Wenjie Li Yuxiao Zou Longfeng Lv Hualiang Yu Huizhen Ke Ruping Liu Yun Xu Jun Wang Zhou Li | 2022 | Nano Research2022，15，3： | 2 |
| 2 | Expression of acetylated histone 3 in the spinal cord and the effect of morphine on inflammatory pain in rats显示文摘In this study, a rat model of inflammatory pain was produced by injecting complete Freund's adjuvant into the hind paw, and the expression of acetylated histone 3 in the spinal cord dorsal horn was examined using immunohistochemical staining. One day following injection, there was a dramatic decrease in acetylated histone 3 expression in spinal cord dorsal horn neurons. However, on day 7, expression recovered in adjuvant-injected rats. While acetylated histone 3 labeling was present in dorsal horn neurons, it was more abundant in astrocytes and microglial cells. The recovery of acetylated histone 3 expression was associated with a shift in expression of the protein from neurons to glial cells. Morphine injection significantly upregulated the expression of acetylated histone 3 in spinal cord dorsal horn neurons and glial cells 1 day after injection, especially in astrocytes, preventing the transient downregulation. Our results indicate that inflammatory pain induces a transient downregulation of acetylated histone 3 in the spinal cord dorsal horn at an early stage following adjuvant injection, and that this effect can be reversed by morphine. Thus, the downregulation of acetylated histone 3 may be involved in the development of inflammatory pain. | Hua Li Changqi Li Ruping Dai Xudan Shi Junmei Xu Jianyi Zhang Xinfu Zhou Zhiyuan Li Xuegang Luo | 2012 | Neural Regeneration Research2012，7，7： | 1 |
| 3 | Analysis on Attenuation Efficiency of Lightning Current by Lightning Interceptor显示文摘Lightning interception technology is one of the three core technical systems of regional lightning protection theory.Among them,the omni-directional multi-pulse lightning interceptor(hereinafter referred to as lightning interceptor,the same below)has the ability to attenuate lightning current≥40%and significantly reduce the intensity of the spatial electromagnetic field around the lightning point.In order to explore the attenuation mechanism and effect of lightning interceptor to lightning current,this paper analyzed a lightning stroke process at 16:00 on August 19,2022,and tried to explain the attenuation effect of lightning interceptor to lightning current with the physical parameters of lightning stroke. | Hui YANG Zhongqiu SHI Renhong GUO Yixian QIU Qiaobin WEI Ruping ZHOU Yu HUANG | 2023 | Meteorological and Environmental Research2023，14，1： | 1 |
| 4 | BRCA1 involved in regulation of Bcl-2 expression and apoptosis susceptibility to ionizing radiation显示文摘BRCA1 has been proposed to be tightly linked to the resistance of tumor cells to ionizing radiation. The pathway leading to this phenomenon is not yet clear. In this work, we investigated the role of BRCA1 in the apoptosis regulation in response to carbon ion irradiation. We utilized three different cancer cell lines with various states for BRCA1 and p53 to identify the relationship between endogenous BRCA1 and the apoptosis-related genes, and determine whether p53 function would affect the role of BRCA1 in apoptosis regulation. By Western blot analysis, we found that Bax expressions were not significantly changed after irradiation in all of three cell lines. However, Bcl-2 expression showed an up-regulation by endogenous BRCA1 regardless of p53 status. Moreover, the changes in Bcl-2 protein were due to the increase in the transcriptional levels of Bcl-2 mRNA, based on real-time PCR assay. At the same time, BRCA1-deficient cells showed a greater apoptosis susceptibility to irradiation when compared with BRCA1-proficient cells. The results suggest that BRCA1 might exert p53-independent regulative activities for Bcl-2, which seems account for the low apoptosis susceptibility in BRCA1-proficient carcinomas. | WANG YanLing WANG Bing ZHANG Hong LI Ning TANAKA Kaoru ZHOU Xin CHEN RuPing ZHANG Xin | 2011 | Science China(Physics,Mechanics & Astronomy)2011，54，5： | 0 |
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