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41篇 您的检索式:作者名="Ryschich"
    题名 作者 年代 出处 被引量
1Disturbance of hepatic and intestinal microcirculation in experimental liver cirrhosis显示文摘AIM: To analyze hepatic, mesenteric and mucosal microcirculation and leukocyte-endothelium interaction (LEI) in a rat model with liver cirrhosis.METHODS: Hepatic cirrhosis was induced in Wistar rats by gavage with carbon tetrachloride, and intravital videomicroscopy was performed in liver, mesentery and small intestine mucosa. Special emphasis is given on microcirculatory and morphometric changes during cirrhotic portal hypertension.RESULTS: LEI was influenced significantly in the cirrhotic liver but not in the gut. Blood flow measurement showed significant differences among liver, main mesenteric vessels and the mucosa. The results of our study indicate that liver cirrhosis leads to alterations in hepatic and mesenteric blood flow but not in mucosal blood flow.CONCLUSION: The enhanced inflammatory response in hepatic microvessels may be caused by a decrease of antithrombin Ⅲ levels and could be responsible for disturbances of organ pathology.Sasa-Marcel Maksan Eduard Ryschich Zilfi (U|¨)lger Martha Maria Gebhard Jan Schmidt 2005World Journal of Gastroenterology2005,11,6:11
2Increased apoptosis and decreased density of medial smooth muscle cells in human abdominal aortic aneurysms显示文摘Objective To determine the increase of apoptosis and the decrease of smooth muscle cells (SMCs) density in human abdominal aortic aneurysms (AAA). Methods In situ terminal transferase-mediated dUTP nick end labeling (TUNEL) was employed to detect apoptosis of SMCs in patients with AAA (n=25) and normal abdominal aortae (n=10). Positive cells were identified by specific cell marker in combination with immunohistochemistry. Meanwhile SMC counting was performed by anti-α-actin immunohistostaining to compare the SMC density. Results TUNEL staining revealed that there was significantly increased apoptosis in AAAs (average 8.6%) compared with normal abdominal aortae (average 0.95%, P <0.01). Double staining showed that most of these cells were SMCs. Counting of α-actin positive SMCs revealed that medial SMC density of AAAs (37.5±7.6 SMCs /HPF) was reduced by 79.1% in comparison with that of normal abdominal aortae (179.2±16.1 SMCs /HPF,P <0.01). Conclusions Significantly increased SMCs of AAA bear apoptotic markers initiating cell death. Elevated apoptosis may result in a decreased density of SMCs in AAA,which may profoundly influence the development of AAA.张健 Jan Schmidt Eduard Ryschich Hardy Schumacher Jens R Allenberg 2003Chinese Medical Journal2003,,10:6
3Molecular fingerprinting and autocrine growth regulation of endothelial cells in a murine model of hepatocellular carcinoma 显示文摘Ryschich E Lizdenis P Ittrich C 2006Cancer Res2006,66,1:1
4Pancreatic capillary blood flow in an improved model of necrotizing pancreatitis in the rat显示文摘Schmidt J Ebeling D Ryschich E 2002J Surg Res2002,106,2:1
5Intravenous Contrast Medium Aggravates the Impairment of Pancreatic Microcirculation in Necrotizing Pancreatitis in the Rat显示文摘Jan Schmidt Hubert G. Hotz Thomas Foitzik Eduard Ryschich Heinz J. Buhr Andrew L Warshaw Christian Herfarth Ernst Klar 1995Annals of Surgery1995,,3:1
6Induction of an antitumoral immune response by wild-type adeno-associated virus type 2 in an in vivo model of pancreatic carcinoma显示文摘Eisold S Schmidt J Ryschich E 2007Pancreas2007,35,1:1
7Transformation of the microvascular system during multistage tumorigenesis 显示文摘Ryschich E Schmidt J Hammerling G J 2002Int J Cancer2002,97,6:1
8Transformation of the microvascular system during multistage tumorigenesis显示文摘RYSCHICH E SCHMIDT J HAMMERLING G J 2002Int J Cancer2002,97,6:1
9Chronic alcohol intake increases the severity of pancreatitis induced by acute alcohol administra- tion, hyperlipidemia and pancreatic duct obstruction in rats 显示文摘Grauvogel J Daemmrich TD Ryschich E 2010Pancre- atology2010,10,5:1
10Transferrin receptor is a marker of malignant phenotype in human pancreatic cancer and in neuroendocrine carcinoma of the pancreas显示文摘Ryschich E Huszty G Knaebel HP 2004European Journal of Cancer2004,40,9:1
11Induction of an antitumoral immune response by wild-type adeno-associated virus type 2 in an in vivo model of pancreatic carcinoma显示文摘Eisold S Schmidt J Ryschich E 0,,:1
12Pancreatic capillary blood flow in an improved model of nercotizing pancreatitis in the rat显示文摘Schmidt J Ebeling D Ryschich E 2002J Surg Res2002,106,1:1
13Inducible nitric oxide synthase is present in human abdominal aortic aneurysm and promotes oxidative vascular injury显示文摘Zhang J Schmidt J Ryschich E 2003J Vasc Surg2003,38,:1
14Different radiogenic effects on microcirculation in healthy pancreas and in pancreatic carcinoma of the rat显示文摘Ryschich E Schmidt J Loeffler T 2003Ann Surg2003,237,4:1
15Endothelial plasticity governs the site‐specific leukocyte recruitment in hepatocellular cancer显示文摘Olga Salnikova Kai Breuhahn Natalie Hartmann Jan Schmidt Eduard Ryschich 2013Int J Cancer2013,,10:1
16Isovolemic hemodilution with dextran prevents contrast medium induced impairment of pancreatic microcirculation in necrotizing pancreatitis of the rat显示文摘Hotz HG Schmidt J Ryschich EW 1995Am J Surg1995,169,1:1
17Promotion of tumor cell migration hy extracellular matrix proteins in human pancreatic cancer显示文摘Ryschich E Khamidjanov A Kerkadze V 2009Pancreas2009,38,80:1
18Characterization and reduction of ischemia/reperfusion injury after experimental pancreas transplantation 显示文摘Mayer H Schmidt J Thies J Ryschich E 1999J Gastrointest Surg1999,3,2:1
19Intracapillary leucocyte accumulation as a novel antihaemorrhagic mechanism in acute pancreatitis in mice显示文摘Ryschich E Kerkadze V Deduchovas O 2009Gut2009,58,11:1
20Telomerase - specific T - cells kill pancreatic tumor cells in vitro and in vivo 显示文摘Schmidt J Ryschich E Sievers E 2006Cancer2006,106,4:1
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