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| 1 | Arteriovenous fistulas and digital hypoperfusion ischemic syndrome in patients on hemodialysis显示文摘AIM: To determine survival parameters as well as characteristics of patients with this syndrome. METHODS: The investigation was conducted over a period of eight years, as a prospective, non-randomized, clinical study which included 204 patients, treated by chronic hemodialysis. Most patients received hemodialysis 12 h per week. As vascular access for hemodialysis all subjects had an arteriovenous fistulae. Based on surveys the respondents were divided into groups of patients with and without digital hypoperfusion ischemic syndrome. Gender, demographic and anthropometric characteristics, together with comorbidity and certain habits, were recorded. During this period 34.8% patients died.RESULTS: Patients with digital hypoperfusion ischemic syndrome were older than those without ischemia(P = 0.01). Hemodialysis treatment lasted significantly longer in the patients with digital hypoperfusion ischemic syndrome(P = 0.02). The incidence of cardiovascular disease(P < 0.001) and diabetes mellitus(P = 0.01), as well as blood flow through the arteriovenous fistula(P = 0.036), were higher in patients with digital hypoperfusion ischemic syndrome. Statistically significant differences also existed in relation to oxygen saturation(P = 0.04). Predictive parameters of survival for patients with digital hypoperfusion ischemic syndrome were: adequacy of hemodialysis(B =-3.604, P < 0.001), hypertension(B =-0.920, P = 0.018), smoking(B =-0.901, P = 0.049), diabetes mellitus(B = 1.227, P = 0.005), erythropoietin therapy(B = 1.274, P = 0.002) and hemodiafiltration(B =-1.242, P = 0.033). KaplanMeier survival analysis indicated that subjects with and without digital hypoperfusion ischemic syndrome differed regarding the length of survival(P < 0.001), i.e., patients with confirmed digital hypoperfusion ischemic syndrome died earlier.CONCLUSION: Survival was significantly longer in the patients without digital hypoperfusion ischemic syndrome. | Radojica V Stolic Goran Z Trajkovic Dijana J Miric Bojana Kisic Zorana Djordje Goran Lj Azanjac Marijana S Stanojevic Dragica Z Stolic | 2013 | World Journal of Nephrology2013，2，2： | 8 |
| 2 | Evaluation of reference evapotranspiration equations under humid conditions 显示文摘 | TRAJKOVIC S KOLAKOVIC S | 2009 | Water Resources Management2009，23，14： | 1 |
| 3 | Analysis of Changes in Meteorological Variables Using Mann-Kendall and Sen' s Slope Estimator Statistical Tests in Serbia显示文摘 | GOCIC M TRAJKOVIC S | 2013 | Global and Planetary Change2013，100，： | 1 |
| 4 | Estimating reference evapotranspiration using limited weather data显示文摘 | TRAJKOVIC S KOLAKOVIC S | 2009 | Journal of Irrigation Drainage Engineering2009，135，4： | 1 |
| 5 | Possible virulence factors of Staphylococcus sciuri显示文摘 | STEPANOVIC S VUKOVICC D TRAJKOVIC V | 2001 | Fems Microbiology Letters2001，199，1： | 1 |
| 6 | Tissue-protective effects of fullere nol C60 (OH)24 and amifostine in irradiated rats 显示文摘 | Trajkovic S Dobric S Jacevic V Dragojevic-Simic V Milovanovie Z Dordevic A | 2007 | Colloids Surf B Biointerfaces2007，58，： | 1 |
| 7 | Forecasting of reference evapot ranspiration by artificial neural networks显示文摘 | Trajkovic S Todorovic B Stankovic M | 2003 | Journal of Irrigation and Drainage Engineering2003，129，6： | 1 |
| 8 | Forecasting of reference evapotranspiration by artificial neural networks 显示文摘 | Trajkovic S Todorovic B Stankovic M | 2003 | Journal of Irrigation and Drainage Engineering2003，129，6： | 1 |
| 9 | Mixture design evaluation of drug release from matrix tablets containing carbomer and HPMC显示文摘 | Petrovic A Cvetkoviae N Trajkovic S | 2006 | J Control Release2006，116，2： | 1 |
| 10 | Gene polymorphisms of 22 cytokines in Macedonian children with atopic dermatitis显示文摘 | Stavric K Peova S Trajkov D | 2012 | Iran J Allergy Asthma Immunol2012，11，1： | 1 |
| 11 | Spatio-temporal patterns of precipitation in Ser- bia 显示文摘 | Gocic M Trajkovic S | 2013 | Theoretical and Applied Climatology2013，117，34： | 1 |
| 12 | FP-GA Controlled Pneumatic Variable Valve Actua-tion显示文摘 | Trajkovic S Milosavljevic A Tunestal P | 2006 | SAE Paper2006，，： | 1 |
| 13 | Astrocyte - in- duced regulatory T cells mitigate CNS autoimmunity 显示文摘 | Trajkovic V Vuckovic Q Stosic - Grujiclc S | 2004 | Glia2004，47，2： | 1 |
| 14 | Testing hourly reference evapotranspiration approaches using lysimeter measurements in a semiarid climate 显示文摘 | Trajkovic S | 2010 | Hydrology Research2010，41，1： | 1 |
| 15 | Forecasting of reference evapotranspiration by artificial neural networks显示文摘 | S Trajkovic B Todorovic M Stankovic | 2003 | Journal of Irrigation and Drainage Engineering2003，129，6： | 1 |
| 16 | Forecasting of reference evapotranspiration by artificial neural networks显示文摘 | Trajkovic S Todorovic B Stankovic M | 2003 | J Irrig Drain Eng2003，129，6： | 1 |
| 17 | Hargreaves versus Penman-Monteith under Humid eonditions 显示文摘 | TRAJKOVIC S | 2007 | Journal of Irrigation and Drainage Engineering2007，133，1： | 1 |
| 18 | Forecasting of reference evapotranspiration by artificial neural networks 显示文摘 | Trajkovic S Todorovic B Stankovic M | 2003 | Journal of Irrigation and Drainage Engineering2003，129，6： | 1 |
| 19 | Influence of 1-methylcyclopropene (1-MCP)on postharvest storage quality in green bell pepper fruit显示文摘 | Ilic Z S Trajkovic R Perzelan Y | 2012 | Food and Bioprocess Technology2012，5，： | 1 |
| 20 | Validation of the chronic liver disease questionnaire in Serbian patients显示文摘AIM:To translate into Serbian and to investigate the validity of the cross-culturally adapted the chronic liver disease questionnaire(CLDQ).METHODS:The questionnaire was validated in 103 consecutive CLD patients treated between October 2009 and October 2010 at the Clinic for Gastroenterology,Clinical Centre of Serbia,Belgrade(Serbia).Exclusion criteria were:age < 18 years,psychiatric disorders,acute complications of CLD(acute liver failure,variceal bleeding,and spontaneous bacterial peritonitis),hepatic encephalopathy(grade > 2)and liver transplantation.Evaluation of the CLDQ was done based on the following parameters:(1)acceptance is shown by the proportion of missing items;(2)internal reliabilities were assessed for multiple item scales by using Cronbach alpha coefficient;and(3)in order to assess whether the allocation of items in the domain corresponds to their distribution in the original questionnaire(construction validity),an exploratory factor analysis was conducted.Discriminatory validity was determined by comparing the corresponding CLDQ score/sub-score in patients with different severity of the diseases.RESULTS:The Serbian version of CLDQ questionnaire completed 98% patients.Proportion of missing items was 0.06%.The total time needed to fill the questionnaire was ranged from 8 to 15 min.Assistance in completing the questionnaire required 4.8% patients,while 2.9% needed help in reading,and 1.9% involved writing assistance.The mean age of the selected patients was 53.8 ± 12.9 years and 54.4% were men.Average CLDQ score was 4.62 ± 1.11.Cronbach's alpha for the whole scale was 0.93.Reliability for all domains was above 0.70,except for the domain 'Activity'(0.49).The exploratory factor analysis model revealed 6 factors with eigenvalue of greater than 1,explaining 69.7% of cumulative variance.The majority of the items(66%)in the Serbian version of the CLDQ presented the highest loading weight in the domain assigned by the CLDQ developers:'Fatigue'(5/5),'Emotional function'(6/8),'Worry'(5/5),'Abdominal symptoms'(0/3),'Activity'(0/3),'Systemic symptoms'(3/5).The scales 'Fatigue' and 'Worry' fully corresponded to the original.The factor analysis also revealed that the factors 'Activity' and 'Abdominal symptoms' could not be replicated,and two new domains 'Sleep' and 'Nutrition' were established.Analysis of the CLDQ score/sub-score distribution according to disease severity demonstrated that patients without cirrhosis had lower total CLDQ score(4.86 ± 1.05)than those with cirrhosis Child's C(4.31 ± 0.97).Statistically significant difference was detected for the domains 'Abdominal symptoms' [F(3)= 5.818,P = 0.001] and 'Fatigue' [F(3)= 3.39,P = 0.021].Post hoc analysis revealed that patients with liver cirrhosis Child's C had significantly lower sub-score 'Abdominal symptoms' than patients without cirrhosis or liver cirrhosis Child's A or B.For domain 'Fatigue',patients with cirrhosis Child's C had significantly lower score,than non-cirrhotic patients.CONCLUSION:The Serbian version of CLDQ is well accepted and represents a valid and reliable instrument in Serbian sample of CLD patients. | Dusan Dj Popovic Nada V Kovacevic Darija B Kisic Tepavcevic Goran Z Trajkovic Tamara M Alempijevic Milan M Spuran Miodrag N Krstic Rada S Jesic Zobair M Younossi Tatjana D Pekmezovic | 2013 | World Journal of Gastroenterology2013，19，30： | 1 |
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