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| 1 | Is the pain in chronic pancreatitis of neuropathic origin? Support from EEG studies during experimental pain显示文摘AIM: To prove the hypothesis that patients with chronic pancreatitis would show increased theta activity during painful visceral stimulation. METHODS: Eight patients and 12 healthy controls underwent an experiment where the esophagus was electrically stimulated at the pain threshold using a nasal endoscope. The electroencephalogram (EEG) was recorded from 64 surface electrodes and 'topographic matching pursuit' was used to extract the EEG information in the early brain activation after stimulation. RESULTS: A major difference between controls and patients were seen in delta and theta bands, whereas there were only minor differences in other frequency bands. In the theta band, the patients showed higher activity than controls persisting throughout the 450 ms of analysis with synchronous brain activation betweenthe channels. The main theta components oscillated with 4.4 Hz in the patients and 5.5 Hz in the controls. The energy in the delta (0.5-3.5 Hz) band was higher in the controls, whereas the patients only showed scattered activity in this band. CONCLUSION: The differences in the theta band indicate that neuropathic pain mechanisms are involved in chronic pancreatitis. This has important implications for the understanding and treatment of pain in these patients, which should be directed against drugs with effects on neuropathic pain disorders. | AsbjФrn M Drewes Maciej Gratkowski Saber AK Sami Georg Dimcevski Peter Funch-Jensen Lars Arendt-Nielsen | 2008 | World Journal of Gastroenterology2008，14，25： | 4 |
| 2 | Immunization against Egyptian Schistosoma mansoni infection by multivalent DNA vaccine显示文摘由几抗原组成的多价的疫苗的发展是对不同寄生虫紧张和寄生虫生命周期阶段创造宽广范围的保护的一条新奇途径。我们以前证实了血吸虫 Sm21.7 和 Sm Fimbrin (SmFim ) 蛋白质能在老鼠导致保护。因此,这研究试图构造多价的 DNA 疫苗的 Sm21.7-SmFim/pBudCE4.1 并且评估它的有免疫力的功效。二血吸虫 mansoni 基因, Sm21.7 和 SmFim 的开的读物框架,被插入到为独立人士设计的真核细胞的表示原生质标志 pBudCE4.1 在哺乳动物的房间的二基因的表示。评估在里面在老鼠的多价的 Sm21.7-SmFim/pBudCE4.1 DNA 疫苗和它的免疫学的效果的 vitro 表示, recombinant 原生质标志 Sm21.7-SmFim/pBudCE4.1 习惯于 mRNA 的 transfect 293T 房间,和表示,蛋白质用反向的抄写聚合酶链反应和蛋白质印迹分析被检验。然后 Sm21.7-SmFim/pBudCE4.1 到的能力免于 S。mansoni 挑战感染在老鼠的种痘以后根据蠕虫负担和鸡蛋减小率被分析。种牛痘的老鼠出现了保护(56%) 的重要水平,和在数字和尺寸的减少,和在细胞的侧面的变化, granulomas。分别地,在肝和肠的鸡蛋减小是 41.53% 和 55.63% 相对仅仅收到了空向量的老鼠同样坚定。除了在蠕虫生存能力的减小,蠕虫肥沃和鸡蛋孵化能力被观察在使免疫的组跟随挑战感染。结果证明 Sm21.7-SmFim/pBudCE4.1 能表示 Sm2 1.7 和 SmFim mRNA 和蛋白质。连接酶的免疫吸着剂试金和蛋白质印迹分析显示使免疫的老鼠对 Sm21.7-SmFim/pBudCE4.1 产生了特定的免疫球蛋白 G。这些结果与多价的 S 建议那种痘。mansoni DNA 疫苗(SmFim-Sm21.7/pBudCE4.1 ) 不仅在蠕虫和卵负担导致重要减小,而且显著地减少卵 granulomas 的尺寸。在摘要,多价的疫苗与保护的重要水平刺激了特定的免疫并且反病理学的效果。 | Mahmoud H Romeih Hanem M Hassan Tarek S Abou Shousha Mohamed A Saber | 2008 | Acta Biochimica et Biophysica Sinica2008，40，4： | 3 |
| 3 | Magnetic properties of a transverse spin-(1/2) Isingfilm显示文摘 | Saber M Ainane A Dujardin F etal | 1999 | PhysRev B1999，59，10： | 2 |
| 4 | Consensus problems in networks of agents with switching topology and time delays 显示文摘 | Saber O R Murray R M | 2004 | IEEE Trans on Autoatic Control2004，49，9： | 1 |
| 5 | Epilepsy and pregnancy : lamotrigine as main drug used 显示文摘 | Sabers A Dam M A - Rogvi - Hansen B | 2004 | Acta Neurol Stand2004，109，： | 1 |
| 6 | AES and XPS Study on the Tarnishing of Silver in Alkaline Sulphide Solutions显示文摘 | SABER T M H WARRAKY A A El | 1988 | Journal of Materials Science1988，23，4： | 1 |
| 7 | Consensus problems in networks ofagents with switching topology and time- delays显示文摘 | R Olfati -Saber R M Murray | 2004 | IEEE Trans- actions on Automatic Control2004，49，9： | 1 |
| 8 | Performance of nanofihration membrane in a vibrating module (VSEP-NF) for arsenic removal 显示文摘 | Saber Ahmed Rasul M G | 2010 | Desalination2010，252，13： | 1 |
| 9 | Cognitive function and antieonvulsant therapy : effect of monotherapy in epilepsy显示文摘 | SABERS A MOLLER A DAM M | 1995 | Acta Neurol Scand1995，92，1： | 1 |
| 10 | Consensus problems in networks of agents with switching topology and time-delays 显示文摘 | OLFATI SABER R MURRAY R M | 2004 | IEEE Transactions on Automatic Control2004，49，9： | 1 |
| 11 | New Static Var Compensator Control Strategy and Coordina- tion with Under-load Tap Changer显示文摘 | Flexible AC Transmission Sys- in England by TJ lnternation ABDEL-RAHMAN M H YOUSSEF F M H SABER A A | 2006 | IEEE Transactions on Power Delivery2006，21，3： | 1 |
| 12 | Hierarchical Watermarking for Secure Image Authentication with Localization显示文摘 | Celik M U Sharma G Saber E | 2002 | IEEE Trans on Image Processing2002，11，6： | 1 |
| 13 | Sodium current and potassium transient outward current genes in Brugada syndrome: screening and bioinformatics显示文摘 | Holst AG Saber S Houshmand M | 2012 | Can J Cardiol2012，28，2： | 1 |
| 14 | Hierarchical watermarking for secure image authentication with localization显示文摘 | Celik M U Sharma G Saber E | 2002 | IEEE Transactions on Image Processing2002，11，6： | 1 |
| 15 | Hierarchical watermarking for secure image authentication with localization显示文摘 | Celik M U Sharma G Saber E | 2002 | IEEE Transactions on Image Processing2002，11，6： | 1 |
| 16 | The critical properties of the BaxSr1-xTiO3 solid solution显示文摘 | SABER M AINANE A ESSAOUDI I | 2009 | Physica B2009，404，1： | 1 |
| 17 | Hierarchical watermarking for secure image authentication with localization显示文摘 | Celik M U Sharma G Saber E | 2002 | IEEE Tmns on Image Processing2002，11，6： | 1 |
| 18 | Single-incision laparoscopic sleeve gaslrectomy (SILS): a novel technique 显示文摘 | Saber A Elgamal M llawi E Rao A | 2008 | Obes Surg2008，1800，： | 1 |
| 19 | Consensus seeking in multi-agent systems under dynamically changing interaction topologies显示文摘 | SABER O MURRAY R M | 2005 | IEEE Transactions on Automation and Control2005，50，5： | 1 |
| 20 | Consensus problems in networks of agents with switching topology and time-delays 显示文摘 | Saber R O Murray R M | 2004 | IEEE Transactions on Automatic Control2004，49，9： | 1 |
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