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1Analysis of colonoscopic perforations at a local clinic and a tertiary hospital显示文摘AIM:To define the clinical characteristics,and to assess the management of colonoscopic complications at a local clinic.METHODS:A retrospective review of the medical records was performed for the patients with iatrogenic colon perforations after endoscopy at a local clinic between April 2006 and December 2010.Data obtained from a tertiary hospital in the same region were also analyzed.The underlying conditions,clinical presentations,perforation locations,treatment types(operative or conservative) and outcome data for patients at the local clinic and the tertiary hospital were compared.RESULTS:A total of 10 826 colonoscopies,and 2625 therapeutic procedures were performed at a local clinic and 32 148 colonoscopies,and 7787 therapeutic procedures were performed at the tertiary hospital.The clinic had no perforations during diagnostic colonoscopy and 8(0.3%) perforations were determined to be related to therapeutic procedures.The perforation rates in each therapeutic procedure were 0.06%(1/1609) in polypectomy,0.2%(2/885) in endoscopic mucosal resection(EMR),and 3.8%(5/131) in endoscopic submucosal dissection(ESD).Perforation rates for ESD were significantly higher than those for polypectomy or EMR(P < 0.01).All of these patients were treated conservatively.On the other hand,three(0.01%) perforation cases were observed among the 24 361 diagnostic procedures performed,and these cases were treated with surgery in a tertiary hospital.Six perforations occurred with therapeutic endoscopy(perforation rate,0.08%;1 per 1298 procedures).Perforation rates for specific procedure types were 0.02%(1 per 5500) for polypectomy,0.17%(1 per 561) for EMR,2.3%(1 per 43) for ESD in the tertiary hospital.There were no differences in the perforation rates for each therapeutic procedure between the clinic and the tertiary hospital.The incidence of iatrogenic perforation requiring surgical treatment was quite low in both the clinic and the tertiary hospital.No procedure-related mortalities occurred.Performing closure with endoscopic clipping reduced the C-reactive protein(CRP) titers.The mean maximum CRP titer was 2.9 ± 1.6 mg/dL with clipping and 9.7 ± 6.2 mg/dL without clipping,respectively(P < 0.05).An operation is indicated in the presence of a large perforation,and in the setting of generalized peritonitis or ongoing sepsis.Although we did not experience such case in the clinic,patients with large perforations should be immediately transferred to a tertiary hospital.Good relationships between local clinics and nearby tertiary hospitals should therefore be maintained.CONCLUSION:It was therefore found to be possible to perform endoscopic treatment at a local clinic when sufficient back up was available at a nearby tertiary hospital.Toshihiko Sagawa Satoru Kakizaki Haruhisa Iizuka Yasuhiro Onozato Naondo Sohara Shinichi Okamura Masatomo Mori 2012World Journal of Gastroenterology2012,18,35:5
2芦丁对绿豆幼苗营养生长的影响及其与IAA的相互作用(英文)显示文摘观察了植物体内的天然黄酮芦丁和吲哚乙酸(IAA)对绿豆幼苗营养生长的影响并测定胚轴中的芦丁和IAA含量.光照条件下芦丁(60μg/mL以下)处理对绿豆幼苗生长有一定促进作用,表现为胚轴和主根伸长加快、侧根数目增多、鲜重或干重增加;而光照条件下更高浓度芦丁(80μg/mL以上)处理及黑暗条件下芦丁(20~100μg/mL)处理对绿豆幼苗生长有抑制作用.当培养基中的芦丁浓度为60~80 μg/mL时,光照下的幼苗比暗处理的幼苗在胚轴中积累更多的芦丁;而芦丁浓度为40μg/mL以下和接近100μg/mL时幼苗在光照下累积的芦丁较暗处理的幼苗更少.0.1μg/mL以上的IAA促进芦丁的累积而进一步抑制幼苗胚轴和主根的伸长.当培养基中含有40 μg/mL的芦丁和0.5μg/mL的IAA时,胚轴中累积的芦丁达到高峰.芦丁降低黄化幼苗内源性IAA在胚轴中的累积,并抑制幼苗对IAA的吸收.梁红 Yoneo Sagawa Qing Xiao LI 2005植物生理与分子生物学学报2005,31,4:4
3碳化过程中大水灰比水泥浆体孔结构的变化(英文)显示文摘使用特殊的增黏剂与聚羧酸减水剂,制备了掺加石灰石粉、高炉矿渣、硅灰等混合材的普通波特兰水泥浆体和和低热硅酸盐水泥浆体(水粉比为1.0)。这些水泥浆体在20℃的水中养护4年后基本完全水化。这些硬化水泥浆体在5%(质量分数)CO2、相对湿度66%和温度20℃条件下进行碳化,对比研究碳化前后水泥浆体孔结构的变化。结果显示:碳化浆体内孔直径大于10nm的孔体积明显减少;碳化浆体的孔径分布向大孔径范围偏移;掺加混合材的硬化水泥浆体结构明显趋于松散;与不掺加任何混合材的水泥浆体相比,掺加混合材的水泥浆体的孔径更大。ASAGA Kiyoshi ITO Syunsuke SUZUKI Yuji SAGAWA Takahumi 2010硅酸盐学报2010,38,9:3
4Effect of the Tensor Force on Charge-Exchange Spin-Dependent Multipole Excitations显示文摘费用交换纺纱偶极子(SD ) 和纺纱四极(平方) 90Zr 的力量功能在前後一致的 HF+RPA 有或没有 Skyrme 相互作用的张肌术语被计算途径。在 SD 和平方转变, RPA 关联戏剧性地与张肌术语胫骨联系了,这被发现力量( Yls ) l = l [?] 1 并且( Yls ) l = 1 个模式向上并且向下,分别地并且也转移力量( Yls ) l = l + 1 个模式向上。联合在之间(Yl = l [?] 1s ) l 并且(Yl = l + 1s ) l 模式从张肌关联产生是显著的。RPA 张肌关联生产 SD 和平方模式的力量,它在一个宽得多的精力范围是分布式的,并且(Yls ) l = l [?] 1 个模式统治力量功能的高精力部分。这些精力移动和不同模式的联合效果能是由在一种可分离的形式表示有限范围张肌力量的理解的品质上。[从作者抽象]白春林 张焕乔 张锡珍 许甫荣 H. Sagawa G. Colo 2010Chinese Physics Letters2010,27,10:2
5Phase II study of S-1, docetaxel and cisplatin combination chemotherapy in patients with unresectable metastatic gastric cancer显示文摘Yasushi Sato Tetsuji Takayama Tamotsu Sagawa Yasuo Takahashi Hiroyuki Ohnuma Syunichi Okubo Naoaki Shintani Shingo Tanaka Masaya Kida Yasuhiro Sato Hidetoshi Ohta Koji Miyanishi Tsutomu Sato Rishu Takimoto Masayoshi Kobune Koji Yamaguchi Koichi Hirata Yos 2010Cancer Chemotherapy and Pharmacology2010,,4:2
6Effects of Tensor Force on Multipole Response in Finite Nuclei显示文摘Cao Ligang G. Colo H. Sagawa P. F. Bortignon L. Sciacchitano 2009近代物理研究所和兰州重离子加速器实验室年报:英文版2009,,1:2
7Augmentation of leption synthesis and secretion through activation of protein kinases A and C in culured human trophoblastic cells显示文摘Yuyas Sagawa N Ogawa Y 1998J Clin Endocrinol Metab1998,83,10:1
8Role of leptin in pregnancy 显示文摘Sagawa N Yura S Itoh H 2002Placenta2002,,:1
9Angiotensin receptor blockers suppress antigen-specific T cell responses and ameliorate collagen-induced arthritis in mice显示文摘Sagawa K Nagatani K Komagata Y 2005Arthritis Rheum2005,52,6:1
10Hypemuclei inthe deformed Skyrme-Hartree-Fock approach显示文摘Zhou X R Schulze H J Sagawa H 2007PhysicalReview C2007,76,03:1
11Pbarmackinelics and bioavailability of the isoflavone hiochanin A in rats显示文摘Moon YJ Sagawa K Frederick K 2006AAPS J2006,8,3:1
12Noneadipose tissue production of leptin:Leptin as a novel placenta-derived hormone in humans显示文摘Masuzaki H Ogawa Y Sagawa N 1997Nature Med1997,3,9:1
13Role of leptin in pregnancy - a review 显示文摘Sagawa N Yura S Itoh H 2002Placenta2002,23,:1
14Augmented placental production of leptin in preeclampsia: possible involvement of placental hypoxia 显示文摘Mise H Sagawa N Matsumoto T 1998J Clin Endocrinol Metab1998,83,9:1
15Cytokine production by T cells infiltrating in the eye of uveitis patients显示文摘Sakaguchi M Sugita S Sagawa K 1998Jpn J Ophthalmol1998,42,:1
16Segmentectomy for roentgenographically occult bronchogenic squamous cell car- cinoma显示文摘Sagawa M Koike T Sato M 2001Ann Thorac Surg2001,71,4:1
17查看详情显示文摘MARGUERON J SAGAWA H HAGINO K 0,,:1
18Miniaturized Hairpin Resonator Filters and Their Application to Receiver Front-End MIC's显示文摘Morikazu Sagawa Kenichi Takahashi Mitsuo Makimoto 1989IEEE Trans Microwave Theory Tech1989,37,12:1
19Argon plasma coagulation forsuccessful treatment of early gastric cancer with intramucosal invasion 显示文摘Sagawa T Takayama T Oku T 2003Gut2003,52,3:1
20Differential effects of two ROCK inhibitors, Fasudil and Y- 27532, on optic nerve regeneration in adult cats 显示文摘Ichikawa M Yoshida J Saito K Sagawa H Tokita Y Watanabe M 2008Brain Res2008,1201,1:1
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