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8篇 您的检索式:作者名="SAIT L"
    题名 作者 年代 出处 被引量
1Mesenchymal stem cell therapy in patients with small bowel transplantation:Single center experience显示文摘AIM:To study the effects of mesenchymal stem cell(MSC) therapy on the prevention of acute rejection and graft vs host disease following small bowel transplantation.METHODS: In our transplantation center, 6 isolated intestinal transplants have been performed with MSC therapy since 2009. The primary reasons for transplants were short gut syndrome caused by surgical intestine resection for superior mesenteric artery thrombosis(n = 4), Crohn's disease(n = 1) and intestinal aganglionosis(n = 1). Two of the patients were children. At the time of reperfusion, the first dose of MSCs cultured from the patient's bone marrow was passedinto the transplanted intestinal artery at a dose of 1000000 cells/kg. The second and third doses of MSCs were given directly into the mesenteric artery through the arterial anastomosis using an angiography catheter on day 15 and 30 post-transplant.RESULTS: The median follow-up for these patients was 10.6 mo(min: 2 mo-max: 30 mo). Three of the patients developed severe acute rejection. One of these patients did not respond to bolus steroid therapy. Although the other two patients did respond to antirejection treatment, they developed severe fungal and bacterial infections. All of these patients died in the 2nd and 3rd months post-transplant due to sepsis. The remaining patients who did not have acute rejection had good quality of life with no complications observed during the follow-up period. In addition, their intestinal grafts were functioning properly in the 13th, 25th and 30th month post-transplant. The patients who survived did not encounter any problems related to MSC transplantation.CONCLUSION: Although this is a small case series and not a randomized study, it is our opinion that small bowel transplantation is an effective treatment for intestinal failure, and MSC therapy may help to prevent acute rejection and graft vs host disease following intestinal transplantation.Sait Murat Do?an Sel?uk K?l?n? Eyüp Kebap?? Cem Tu?men Mustafa ?lmez Cezmi Karaca Alp Gürkan Ma?allah Baran Yusuf Kurtulmu? 2014World Journal of Gastroenterology2014,20,25:3
2A validated stability-indicating normal phase LC method for clopidogrel bisulfate and its impurities in bulk drug and pharmaceutical dosage form显示文摘Durga Rao D Kalyanaraman L Sait S S Venkata Rao P 2010J Pharm Biomed Anal2010,52,:1
3A validated stability- indicating normal phase LC method for clopidogrel bisulfate and its impurities in bulk drug and pharmaceutical dosage form显示文摘Durga Rao D Kalyanaraman L Sait SS 2010Journal of Pha~eutical and Biomedical Analysis2010,52,1:1
4Structure and chromosomal localization of the human salivary mucin gene,MUC7显示文摘Bobek L A Liu J Sait S N 1996Genomics1996,31,3:1
5A defned intestinal colonization microbiota for gnotobiotic pigs 显示文摘LAYCOCK G SAIT L INMAN C 2012Veterinary Immunology and Immunopathology2012,149,34:1
6Unbiased estimation of the liver volume by the Cavalieri principle using magnetic resonance images显示文摘Bünyamin Sahin Mehmet Emirzeoglu Ahmet Uzun Lütfi Incesu Yüksel Bek Sait Bilgic Süleyman Kaplan 2002European Journal of Radiology2002,,2:1
7Thermal behavior of polyamide-6-based intumescent formulations显示文摘Sait C Bourbigot S Bras M L 1997Polym Degrad Stab1997,,58:1
8A study of heart rate and heart rate variability in human subjects exposed to oc- cupational levels of 50 Hz circularly polarised magnetic fields显示文摘Sait M L Wood A W Sadafi H A 1999Medical Engineering and Physics1999,21,5:1
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