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| 1 | Evaluation of mannitol effect in patients with acute hepatic failure and acute-on-chronic liver failure using conventional MRI,diffusion tensor imaging and in-vivo proton MR spectroscopy显示文摘AIM:To evaluate the effect of an intravenous bolus of mannitol in altering brain metabolites, brain water content, brain parenchyma volume, cerebrospinal fluid (CSF) volume and clinical signs in controls and in patients with acute liver failure (ALF) and acute-on-chronic liver failure (ACLF), by comparing changes in conventional magnetic resonance imaging (MRI), in vivo proton magnetic resonance spectroscopy (PMRS) and diffusion tensor imaging (DTI) before and after its infusion.METHODS: Five patients each with ALF and ACLF in grade 3 or 4 hepatic encephalopathy and with clinical signs of raised intracranial pressure were studied along with five healthy volunteers. After baseline MRI, an intravenous bolus of 20% mannitol solution was given over 10 min in controls as well as in patients with ALF and ACLF. Repeat MRI for the same position was acquired 30 min after completing the mannitol injection. RESULTS: No statistically significant difference was observed between controls and patients with ALF and ACLF in metabolite ratios, DTI metrics and brain volume or CSF volume following 45 min of mannitol infusion. There was no change in clinical status at the end of post-mannitol imaging. CONCLUSION: The osmotic effect of mannitol did not result in significant reduction of brain water content, alteration in metabolite ratios or any change in the clinical status of these patients during or within 45 min of mannitol infusion. | Vivek A Saraswat Sona Saksena Kavindra Nath Pranav Mandal Jitesh Singh M Albert Thomas Ramkishore S Rathore Rakesh K Gupta | 2008 | World Journal of Gastroenterology2008，14，26： | 2 |
| 2 | Long-term outcome of patients with drug-refractory atrial flutter and fibrillation after single- and dual- site atrial pacing for arrhythmia prevention显示文摘 | Delfaut P Saksena S Prakash A | 1998 | J Am Coll Cardiol1998，32，： | 1 |
| 3 | Dual site atrial pacing for the acute and chronic prevention of atrial fibrillation:A prospective study显示文摘 | Saksena S Hill M | 1995 | Am Coll Cardiol1995，25，： | 1 |
| 4 | Impartance and effects of attered workplace ergonomics in modem radiology suites 显示文摘 | Harisinghani M G Blake M A Saksena M | 2004 | Radiographics2004，24，2： | 1 |
| 5 | Prevention of recurrent atrial fibrillation with chronic dual site right atrial pacing显示文摘 | Prakash a Hill M | 1996 | J Am Coll Cardiol1996，28，： | 1 |
| 6 | Improved suppression of recurrent atrial fibrilliation with dual site right atrial pacing and antiarrhythmic drug therapy显示文摘 | Saksena S Prakash A Ziegler P | 2002 | J Am Coll Cardiol2002，40，6： | 1 |
| 7 | Effect of solution pH and ionic strength on the separation of albumin from immuno- globulins (IgG) by selective filtration显示文摘 | Saksena S Zydney A L | 1994 | Biotechnol Bioeng1994，43，： | 1 |
| 8 | Recurrent haemarthrosis following total knee replacement 显示文摘 | Saksena J Platts A D Dowd G S | 2009 | The Knee2009，17，1： | 1 |
| 9 | Improved suppression of recurrent atrial fibrillation with dual-site right atrial pacing and antiarrhythmic drug therapy 显示文摘 | Saksena S Prakash A Ziegler P | 2002 | J Am Coil Cardiol2002，40，： | 1 |
| 10 | Acute effects of dual-site right atrial pacing in patients with spontaneous and inducible atrial flutter and fibrillation显示文摘 | Prakash A Saksena S Hill M | 1997 | J Am Coll Cardiol1997，29，5： | 1 |
| 11 | A comparative e- valuation of intranasal dexmedetomidine, midazolam and ketamine for their sedative and analgesic properties : a triple blind random- ized study显示文摘 | Surendar M N Pandey R K Saksena A K | 2014 | J Clin Pediatr Dent2014，38，3： | 1 |
| 12 | An enhancement multizone model and its application to optimum placement of CBW sensors 显示文摘 | ARVELO J BRANDT A ROGER R P SAKSENA A | 2002 | ASHRAE Trans2002，108，2： | 1 |
| 13 | Concise asymmetric routes to 2,2,4-trisubstituted tetrahydrofurans via chiral titanium imide enolates: key intermediates towards synthesis of highly active azole antifungals SCH 51048 and SCH 56592显示文摘 | Saksena A K Girijavallabhan V M Wang H Y | 1996 | Tetrahedron Lett1996，37，32： | 1 |
| 14 | New generation of implantable pacemaker defibrillators for ventricular and atrial tachyarrhythmias显示文摘 | Saksena S Prakash A Madan N | 2006 | Arch Mal Coeur Vaiss2006，89，1： | 1 |
| 15 | Multisite electrode pacing for prevention of atrial fibrillation显示文摘 | Saksena S Delfaut P Prakash A | 1996 | Cardiovasc Electrophysiol1996，9，8： | 1 |
| 16 | Long-term outcome in patients with drug-refractory atrial flutter and fibrillation after single-anddual-site right atrial pacing for arrhythmia prevention显示文摘 | Delfaut P Saksena S Prakash A | 1998 | JACC1998，32，： | 1 |
| 17 | Diffusion tensor imaging in late posttraumatie epilepsy显示文摘 | Gupta RK Saksena S Agarwal A | 2005 | Epilepsia2005，46，9： | 1 |
| 18 | Long-term outcome of patients with drug-refractory atrial flutter and fibrillation after single-and dual-site right atrial pacing for arrhythmia prevention显示文摘 | Delfaut P Saksena S Prakash A | 1998 | J Am Coll Cardiol1998，32，7： | 1 |
| 19 | International consensus on nomenclature and classification of atrial fibrillation: A collaborative project of the Working Group on Arrhythmias and the Working Group of Cardiac Pacing of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology显示文摘 | Levy S Canon A J Saksena S | 2003 | J Cardiovasc Electrophysiol2003，14，4： | 1 |
| 20 | A novel pentasaccharide from immunostimulant oligosaccharide fraction of buffalo milk显示文摘 | Saksena R Deepak D Khare A | 1999 | Biochimica et Biophysica Acta(BBA)-General Subjects1999，1428，2： | 1 |
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