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| 1 | Control of Arabidopsis meristem developraent by thioredoxin dependent regulation of intercellular transport显示文摘 | BENITEZ-ALFONSO Y CILLIA M SAN ROMAN A | 2009 | Proceedings of the National Academy of Sciences2009，106，9： | 1 |
| 2 | Polymeric matrices based on graft copolymers of PCL onto acrylic backbones for releasing antitumoral drugs 显示文摘 | ABRAHAM GA GALLARDO A SAN ROMAN J | 2003 | J Biomed Mater Res A2003，64，4： | 1 |
| 3 | Erythroplasia of Queyrat with urethral involvement: treatment with carbon dioxide laser vapor- ization显示文摘 | Del Losada JP Ferre A San Roman B | 2005 | Dermatol Surg2005，31，111： | 1 |
| 4 | Contemplating the bright future of stem cell therapy for cardiovascular disease显示文摘 | Sanchez PL San Roman JA Villa A | 2006 | Nat Clin Pract Cardiovasc Med2006，3，1： | 1 |
| 5 | Natural history and serial morphology of aortic intramural hematoma: fl novel variant of aortic dissection显示文摘 | Vilacosta I San Roman J A Ferreiros J | 1997 | Am Heart J1997，134，3： | 1 |
| 6 | Risk averse scheduling by a PEV aggregator under uncertainty 显示文摘 | Momber I Siddiqui A Gomez San Roman T | 2015 | IEEE Transactions on Power Systems2015，30，2： | 1 |
| 7 | Erythroplasia of Queyrat with urethral involvement: treatment with carbon dioxide laser vaporization显示文摘 | Del Losada JP Ferre A San Roman B | 2005 | Drmatd Surg2005，31，11： | 1 |
| 8 | Acute aortic syndrome显示文摘 | VILACOSTA I SAN ROMAN J A | 2001 | Heart2001，85，： | 1 |
| 9 | Frequency and implications of resetting and entrainment with right atrial stimulation in atrial flutter显示文摘 | Arenal A Almendral J San Roman D | | 0，，： | 1 |
| 10 | Characterization of the Arabidopsis clb6 mutant illustrates the importance of posttranscrip- tional regulation of the methyl-D-erythritol 4-phosphate pathway显示文摘 | Guevara-Garcia A San Roman C Arroyo A | 2005 | Plant Cell2005，17，： | 1 |
| 11 | The effect of natural UV-B radiation on a perennial Salicornia salt-marsh in Bahía San Sebastián, Tierra del Fuego, Argentina: a 3-year field study显示文摘 | O A Bianciotto L B Pinedo N A San Roman | 2003 | J Photochem Photobiol B-Biol2003，70，： | 1 |
| 12 | Impairment of intracellular calcium homoeostasis in the exocrine pancreas after caerulein-indueed acute pancreatitis in the rat 显示文摘 | Bragado M J San roman JI Gonzales A | 1997 | Clinical Scierwe1997，91，6： | 1 |
| 13 | Acute coronary syndronle in infective endoearditi 显示文摘 | MANRAHO M C VILACOSTAL I SAN ROMAN J A | 2007 | Rev EspCardiol2007，60，1： | 1 |
| 14 | Falloposcopic classification and treatment of fallopian tube lumen disease 显示文摘 | KERIN J F WILLIAMS D B SAN ROMAN G A | 1992 | Fertil1992，57，6： | 1 |
| 15 | Role of Transthoracic and Transesophageal Echocardiography in Right-Sided Endocarditis: One Echocardiographic Modality Does Not Fit All显示文摘 | José Alberto San Román Isidre Vilacosta Javier López Ana Revilla Roman Arnold Teresa Sevilla María J. Rollán | 2012 | Journal of the American Society of Echocardiography2012，，8： | 1 |
| 16 | Controlling the turbo- charger whistling noise in diesel engines 显示文摘 | Calvo J A Diaz V San Roman J L | 2006 | International Journal of Vehicle Noise and Vibration2006，2，1： | 1 |
| 17 | Procedure for determining manu- facturing defects in a diesel engine in a workshop 显示文摘 | Calv J A Diaz V San Roman L | 2010 | Applied Acoustics2010，71，2： | 1 |
| 18 | Contemplating the bright future of stem cell therapy for cardiovascular disease显示文摘 | Sanchez PL San Roman JA Villa A | 2006 | Cardiovase Med2006，3，： | 1 |
| 19 | Prospective application of a bleeding and ischemic risks-adjusted antithrombotic protocol in elderly patients revascularized with everolimus-eluting stents:EPIC05-Sierra75 study显示文摘OBJECTIVES Elderly patients show a higher incidence of ischemic and bleeding events after percutaneous transluminal coron-ary intervention(PCI).We sought to investigate outcomes in elderly patients treated with antithrombotic strategy guided by bleeding and ischemic risks after revascularization with last generation everolimus-eluting stent(EES).METHODS Prospective multicenter registry including patients over 75 years revascularized with EES and antithrombotic ther-apy guided by clinical presentation,PCI complexity and PRECISE DAPT score.Co-primary safety endpoints were:(1)composite of cardiac death,myocardial infarction and stent thrombosis and;(2)bleeding(BARC 2-5).Primary efficacy endpoint was target lesion revascularization.A matched group of patients revascularized with current drug-eluting stents and no such tailored antith-rombotic therapy was used as control.RESULTS Finally,1064 patients were included in SIERRA-75 cohort,80.8±4.2 years,36.6%women,71%acute coronary syn-dromes(ACS)and 53.6%complex PCI.Co-primary safety endpoint of major adverse cardiovascular events was met in 6.2%,co-primary safety endpoint of bleeding in 7.8%and primary efficacy endpoint of TKLR in 1.5%.The multivariable adjusted model showed no significant association of the prescribed short/long dual antiplatelet therapy(DAPT)durations with any endpoint suggesting a well tailored therapy.No stent thrombosis reported in the subgroup with 1-3 months DAPT duration.As compared to control group,bleeding BARC 2-5 was significantly lower in SIERRA-75 group(7.4%vs.10.2%,P=0.04)as well as the net safety-efficacy endpoint(14.3%vs.18.5%,P=0.02).CONCLUSIONS In elderly population,the application of this risks-adjusted antithrombotic protocol after revascularization with last generation EES seems to be associated with an improved prognosis in terms of ischemic and bleeding outcomes. | Jose M de la Torre Hernandez Ramon Lopez Palop Jesus M Jimenez Mazuecos Pilar Carrillo Sáez Alejandro Gutierez-Barrios Eduardo Pinar Belen Cid Luis Fernandez Tamara Garcia Camarero Cristóbal Urbano-Carrillo Juan F Oteo Dominguez Victor A Jimenez Diaz Antonio EGomez Menchero Eladio Galindo Fernández Juan GCórdoba Soriano Raymundo Ocaranza Eduardo ArroyoÚcar Koldobika Garcia San Roman Silvio Leal Ginés Martínez Cáceres Jose A Linares Vicente Georgina Fuertes Ferre Xavier Carrillo Juan CRama Merchán Catia Costa Juan Sanchis Renato Fernandes Alberto Rodrigues Jose M Vegas Valle Hélder Pereira Armando Perez de Prado | 2022 | Journal of Geriatric Cardiology2022，19，5： | 0 |
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