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| 1 | Immunoexpression of cyclooxygenase-2 in primary gastric carcinomas and lymph node metastases显示文摘AIM: To evaluate immunoexpression of cyclooxygenase-2 (COX-2) in primary gastric carcinomas and respective lymph node metastases. METHODS: Immunohistochemistry to analyze COX-2 expression was performed on tissue microarray slices obtained from 36 specimens of gastrectomy and satellite lymph nodes from patients with gastric carcinoma. RESULTS: Immunostaining was seen in most cases, and COX-2 expression was higher in lymph node me-tastases than in corresponding primary gastric tumors of intestinal, diffuse and mixed carcinomas, with a statistically signif icant difference in the diffuse histotype (P = 0.0108). CONCLUSION: COX-2 immunoexpression occurs frequently in primary gastric carcinomas, but higher expression of this enzyme is observed in lymph node metastases of the diffuse histotype. | Paulo RC Almeida Francisco VA Ferreira Cássio C Santos Francisco D Rocha-Filho Raul RP Feitosa Esther AA Falco Belise K Cavada Roberto CP Lima-Júnior Ronaldo A Ribeiro | 2012 | World Journal of Gastroenterology2012，18，8： | 14 |
| 2 | Research advances on the multiple uses of Moringa oleifera: a sustainable alternative for socially neglected population显示文摘Moringa oleifera Lam(Moringaceae) is a plant with high nutritional and medicinal value. Native to India, it is now widely distributed throughout tropical and subtropical regions of the world. Its different parts are sources of proteins, vitamins and minerals and present different pharmacological and biotechnological potential. Moreover, M. oleifera seeds are widely used in water and effluent treatment, for their coagulation, flocculation and sedimentation properties, their ability of improving water quality, by reducing organic matter and microbial load, with special applicability in intensive animal production systems, such as aquaculture. In addition, due to its high nutritional value and several medicinal properties, this tree may act as a nutritional and medical alternative for socially neglected populations. In this context, this review gathers information on M. oleifera, emphasizing its chemical constituents, nutritional, pharmacological and antimicrobial properties, applications in the treatment of water effluents, and ecological and social aspects. | Raimunda Samia Nogueira Brilhante Jamille Alencar Sales Vandbergue Santos Pereira Débora de Souza Collares Maia Castelo-Branco Rossana de Aguiar Cordeiro Célia Maria de Souza Sampaio Manoel de Araújo Neto Paiva Joao Bosco Feitosa dos Santos JoséJúlio CostaSidrim Marcos Fábio Gadelha Rocha | 2017 | Asian Pacific Journal of Tropical Medicine2017，10，7： | 10 |
| 3 | Relationship between Th17 immune response and cancer显示文摘Cancer is the second leading cause of death worldwide and epidemiological projections predict growing cancer mortality rates in the next decades.Cancer has a close relationship with the immune system and,although Th17 cells are known to play roles in the immune response against microorganisms and in autoimmunity,studies have emphasized their roles in cancer pathogenesis.The Th17 immune response profile is involved in several types of cancer including urogenital,respiratory,gastrointestinal,and skin cancers.This type of immune response exerts pro and antitumor functions through several mechanisms,depending on the context of each tumor,including the protumor angiogenesis and exhaustion of T cells and the antitumor recruitment of T cells and neutrophils to the tumor microenvironment.Among other factors,the paradoxical behavior of Th17 cells in this setting has been attributed to its plasticity potential,which makes possible their conversion into other types of T cells such as Th17/Treg and Th17/Th1 cells.Interleukin(IL)-17 stands out among Th17-related cytokines since it modulates pathways and interacts with other cell profiles in the tumor microenvironment,which allow Th17 cells to prevail in tumors.Moreover,the IL-17 is able to mediate pro and antitumor processes that influence the development and progression of various cancers,being associated with variable clinical outcomes.The understanding of the relationship between the Th17 immune response and cancer as well as the singularities of carcinogenic processes in each type of tumor is crucial for the identification of new therapeutic targets. | Hanna Santos Marques Breno Bittencourt de Brito Filipe Antônio França da Silva Maria Luísa Cordeiro Santos Júlio César Braga de Souza Thiago Macêdo Lopes Correia Luana Weber Lopes Nayara Silva de Macêdo Neres Rafael Santos Dantas Miranda Dórea Anna Carolina Saúde Dantas Lorena Lôbo Brito Morbeck Iasmin Souza Lima Amanda Alves de Almeida Maiara Raulina de Jesus Dias Fabrício Freire de Melo | 2021 | World Journal of Clinical Oncology2021，12，10： | 5 |
| 4 | Angiostatic activity of human plasminogen fragments is highly dependent on glycosylation 显示文摘 | Santos I C Silbiger V N Higuchi D A | 2010 | Cancer Sci2010，101，2： | 1 |
| 5 | The analysis of fluorescent whitening agents using reversed-phase HPLC and mass spectrometry显示文摘 | Santos M D L Nerin C Domeno C | 2004 | LCGC Asia Pacific2004，7，3： | 1 |
| 6 | Limiting Carleman weights and anisotropic inverse problems显示文摘 | Dos Santos Ferreira D Kenig C E Salo M | | 0，，： | 1 |
| 7 | Mechanical properties of HSLA bainitic steel subjected to controlled rolling with accelerated cooling显示文摘 | RODRIGUES P C M PERELOMA E V SANTOS D B | 2000 | Materials Science and Engineering: A2000，283，： | 1 |
| 8 | Perceptions of Justice After Recovery Efforts in Internet Purchasing : The Impact on Consumer Trust and Loyalty toward Retailing Sites and Online Shopping in General 显示文摘 | SANTOS C FERNANDES D | 2011 | BAR-brazilian Administration Review2011，8，3： | 1 |
| 9 | Immunohisto-chemical evidence of PTEN in oral squamous cell carcinoma and its correlation with the histological malignancy grading system显示文摘 | Squarize C H Castilho R M Santos P D Jr | 2002 | J Oral Pathol Med2002，31，： | 1 |
| 10 | Diabetes and mitochondrial oxidative stress: a study using heart mitochondria from the diabetic Goto-Kakizaki rat 显示文摘 | Santos D L Palmeira C M Seica R | 2003 | Mol Cell Biochem2003，246，12： | 1 |
| 11 | 查看详情显示文摘 | Santos C N Menses D D S Echegut P Neuville D R Hernandes A C Ibanez A | | 0，，： | 1 |
| 12 | The coerule- us/subcoeruleus complex in rapid eye movement sleep behaviour disor- ders in Parkinson~ disease显示文摘 | Garcia-Lorenzo D Longo-Dos Santos C Ewenczyk C | 2013 | Brain2013，136，7： | 1 |
| 13 | Formation of ultra- fine ferrite mierostructure in warm rolled and annealed C-Mn steel显示文摘 | Santos D B Bruzszek R K Rodrigues P C M | 2003 | Materials Science and Engineering: A2003，346，12： | 1 |
| 14 | Genetic markers in ribosomal DNA for the identification of members of the genus Anisakis (Nematoda : Ascaridoidea) defined by polymerase chain reaction-based restriction fragment length polymorphism 显示文摘 | D'Amelio S Mathiopoulos K D Santos C P | 2000 | Int J Parasitol2000，30，2： | 1 |
| 15 | Impact of climate and hydrology on juvenile fish recruitment towards estuarine nursery grounds in the context of climate change显示文摘 | Vinagre C Santos F D Cabral H N | 2009 | Estuarine Coastal and Shelf Science2009，85，3： | 1 |
| 16 | Layer by Layer TiO2 Thin Films and Photodegradation of Congo Red显示文摘 | Sansiviero M T C Santos D S Job A E | 2011 | J Photochem Photobiol A:Chem2011，220，1： | 1 |
| 17 | Human Papaillomavirus Deoxyribonucleic Acid in Cervical Carcinoma from Primary and Metastatic Sites显示文摘 | Lancaster W D Castellano C Santos C | 1986 | Am J Obstet Gynecol1986，154，12： | 1 |
| 18 | Trade Liberalization, the Exchange Rate and Job Flows in Brazil显示文摘 | Ribeiro EP Corseuil C Santos D | 2004 | Journal of Economic Policy Reform2004，7，4： | 1 |
| 19 | Chemical transformation of abietic acid to new chiral derivatives显示文摘 | Santos C D Zukerman-Schpector J Imamura P M | 2003 | Journal of the BrazilianChemicalSociety2003，14，： | 1 |
| 20 | Evaluation of the effects of two Lactobacillus buchneri strains and sodium benzoate on the characteristics of corn silage in a hot-climate environment显示文摘 | Silva N C D Santos J P D Avila C L S | 2014 | Grassland Science2014，60，3： | 1 |
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