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| 1 | New means to monitor the effect of glucocorticoid therapy in children显示文摘AIM:To study the individual effects of glucocorticoid (GC) therapy on the state ofimmune activation in patient serum.METHODS:We developed a novel assay in which the effect of corticosteroid-treated patient serum on healthy donor peripheral blood mononuclear cells (target cells) was studied,with a panel of markers for effector [interferon (IFN)γ and interleukin (IL)-5] and regulatory T cells (FOXP3 and glucocorticoid-induced tumor necrosis factor receptor,GITR).The study group comprised 19 children with inflammatory bowel disease.The individual effect of patient serum on target cells was analyzed prior to GC therapy and 2 wk later.RESULTS:The effect of GC therapy mediated by patient serum was seen as a decrease in the target cells expression of regulatory T-cell-related markers GITR (median suppression 24%,range of suppression 1%-63%,in 2 cases increase of 6% and 77%,P < 0.01 for mitogen-activated target cells) and FOXP3 (median suppression 33%,range of suppression 0%-79%,in one case an increase of 173%,P < 0.05 for resting cells),and secretion of IFNγ [from a mean of 87 700 pg/mL (SD 33 900 pg/mL) to 60 900 pg/mL (SD 44 200 pg/mL) in mitogen-activated target cells,13 of the cases showed a decrease,P < 0.01].The total or weight-related prednisolone dose did not correlate with the patient-seruminduced changes in the target cell markers.CONCLUSION:GC response could be monitored at an individual level by studying the effect of patient serum on signaling pathways of target immune cells. | Hanne Rintamki Harri M Salo Outi Vaarala Kaija-Leena Kolho | 2010 | World Journal of Gastroenterology2010，16，9： | 4 |
| 2 | 甲醇燃料的船用发动机对空气排放的测量显示文摘Emissions of exhaust gases and particulate matter from a dual fuel marine engine using methanol as fuel with marine gasoil as pilot fuel have been examined for a ferry during operation.The emission factor for nitrogen oxides is lower than what is typically found for marine gasoil but does not reach the tier III limit.The emissions of particulate matter are significantly lower than for fuel oils and similar to what is found for LNG engines.The main part of the particles can be found in the ultrafine range with the peak being at around 18 nm.About 93%of the particles are evaporated and absorbed when using a thermodenuder,and thus a large majority of the particles are volatile.Methanol is a potential future marine fuel that will reduce emissions of air pollutants and can be made as a biofuel to meet emission targets for greenhouse gases. | Erik Fridell Håkan Salberg Kent Salo | 2021 | Journal of Marine Science and Application2021，20，1： | 4 |
| 3 | Mortality in ulcerative colitis and Crohn’s disease. A population-based study in Finland显示文摘 | Pia Manninen Anna-Liisa Karvonen Heini Huhtala Martin Rasmussen Maarit Salo Leena Mustaniemi Ismo Pirttiniemi Pekka Collin | 2011 | Journal of Crohn’s and Colitis2011，，5： | 3 |
| 4 | Seasonal comparison of moss bag technique against vertical snow samples for monitoring atmospheric pollution显示文摘This is the first study seasonally applying Sphagnum papillosum moss bags and vertical snow samples for monitoring atmospheric pollution.Moss bags,exposed in January,were collected together with snow samples by early March 2012 near the Harjavalta Industrial Park in southwest Finland.Magnetic,chemical,scanning electron microscopy-energy dispersive X-ray spectroscopy(SEM-EDX),K-means clustering,and Tomlinson pollution load index(PLI)data showed parallel spatial trends of pollution dispersal for both materials.Results strengthen previous findings that concentrate and slag handling activities were important(dust)emission sources while the impact from Cu–Ni smelter's pipe remained secondary at closer distances.Statistically significant correlations existed between the variables of snow and moss bags.As a summary,both methods work well for sampling and are efficient pollutant accumulators.Moss bags can be used also in winter conditions and they provide more homogeneous and better controlled sampling method than snow samples. | Hanna Salo Anna-Kaisa Berisha Joni M?kinen | 2016 | Journal of Environmental Sciences2016，28，3： | 3 |
| 5 | Impact of Aromatic Concentration in Marine Fuels on Particle Emissions显示文摘The fuel sulfur content in marine fuels has been regulated in Sulfur Emission Control Areas(SECAs) since January 2015. However, other fuel characteristics are also believed to have an impact on particle emissions, particularly on the number of particles emitted. This study investigates the impact of the content of aromatics in fuel. To achieve fuel blends with concentrations of aromatics similar to those found in marine fuel oils, i.e. 20%–30% by volume(%vol.), normal diesel oil(4%–5% vol. aromatics) is doped with a mixture of aromatics. Emission measurements are conducted in test-bed engine facilities and particle emissions over a wide size range are analyzed. Results show a decreased number of particles emitted(or not change) with an increase in the aromatic concentration in fuel. This is because there is a reduction in the cetane number of the fuel with an increased aromatic content, which effects the combustion process and results in decreased particle formation. However, when ignition improver is used to increase the cetane number, particle emissions remain at a lower level than for normal diesel oil; thereby emphasizing the presence of other factors in the formation of particles. | Maria Zetterdahl Kent Salo Erik Fridell Jonas Sjoblom | 2017 | Journal of Marine Science and Application2017，16，3： | 3 |
| 6 | Levels of pyrroloquinoline quinone in various foods显示文摘 | Kumazawa T Salo K Seno H | 1995 | Biochem J1995，307，： | 2 |
| 7 | Optimum Lymphadenectomy for Esophageal Cancer显示文摘 | Nabil P. Rizk Hemant Ishwaran Thomas W. Rice Long-Qi Chen Paul H. Schipper Kenneth A. Kesler Simon Law Toni E. M. R. Lerut Carolyn E. Reed Jarmo A. Salo Walter J. Scott Wayne L. Hofstetter Thomas J. Watson Mark S. Allen Valerie W. Rusch Eugene H. Blacksto | 2010 | Annals of Surgery2010，，1： | 2 |
| 8 | Laminin-5 is a marker of invading cancer cells in some human carcinomas and is coexpressed with there ceptor for urokinase plasminogen activator in bud-ding cancer cells in colon adenocarcinomas显示文摘 | Pyke C Salo S Ralfkiaer E | 1995 | Cancer Res1995，55，： | 1 |
| 9 | Expression of basement membrane type 1V collagen and type 1V collagenases (MMP-2 and MMP-9 ) in human fetal teeth显示文摘 | Heikinheimo K Salo T | 1995 | J Dent Res1995，74，5： | 1 |
| 10 | Limiting Carleman weights and anisotropic inverse problems显示文摘 | Dos Santos Ferreira D Kenig C E Salo M | | 0，，： | 1 |
| 11 | Den- tofacial changes after orthodontic intervention with eruption guidance appliance in the early mixed dentition显示文摘 | Keski-Nisula K Keski-Nisula L Salo H | 2008 | Angle Orthod2008，78，2： | 1 |
| 12 | Matrix metalloproteinase -8 (MMP-8) in pulpal and periapical inflammation and periapieal root -canal exudates 显示文摘 | Wahlgren J Salo T Teronen O | 2002 | International Endodontic2002，35，11： | 1 |
| 13 | Desulfurization of hot coal gas in fluidized bed with regenerable zinc titanate sorbents显示文摘 | Mojtahedi W Salo K Abbasian J | 1994 | Fuel Processing Technology1994，37，1： | 1 |
| 14 | A lock-docking oligo(dT) primer for 5′and 3′RACE PCR显示文摘 | Borson N D Salo W L Drewes R L | 1992 | PCR Methods Appl1992，2，： | 1 |
| 15 | Incipient angiogenesis in Barrett's epithelium and lymphangiogenesis in Barrett' s adenocarcinoma 显示文摘 | Ramo JO Bergman M Salo JA | 2002 | J Clin Oncol2002，20，13： | 1 |
| 16 | Effect of phenytoin and nifedipine on collagen gene expression in human gingival fibro- blasts 显示文摘 | Salo T Oikarinen KS Oikarinen AI | 1990 | J Oral Pathol Med1990，19，9： | 1 |
| 17 | Expression of αvβ6 integrin in oral leukoplakia显示文摘 | Hamidi S Salo T Kainulainen T | 2000 | Br J Cancer2000，82，8： | 1 |
| 18 | Postoperative surveillance in patients with colorectal cancer who have under- gone curative resection: a prospective, multicenter, randomized, controlled trial显示文摘 | Rodriguez-Moranta F Salo J Arcusa A | 2006 | J Clin Oncol2006，24，3： | 1 |
| 19 | Diverse spermatogenic defects in humans caused by Y chromosome deletions encompassing a novel RNA- binding protein gene 显示文摘 | REIJO R LEE T Y SALO P | 1995 | Nature Genetics1995，10，4： | 1 |
| 20 | Nitrogen balance as an indicator of nitrogen leaching in Finland 显示文摘 | Salo T Turtola E | 2006 | Agric Ecosyst Environ2006，113，124： | 1 |
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