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| 1 | Hepatitis D and hepatocellular carcinoma显示文摘Hepatitis D virus(HDV) is a defective circular shape single stranded HDV RNA virus with two types of viral proteins,small and large hepatitis D antigens,surrounded by hepatitis B surface antigen.Superinfection with HDV in chronic hepatitis B is associated with a more threatening form of liver disease leading to rapid progression to cirrhosis.In spite of some controversy in the epidemiological studies,HDV infection does increase the risk of hepatocellular carcinoma(HCC) compared to hepatitis B virus(HBV) monoinfection.Hepatic decompensation,rather than development of HCC,is the first usual clinical endpoint during the course of HDV infection.Oxidative stress as a result of severe necroinflammation may progress to HCC.The large hepatitis D antigen is a regulator of various cellular functions and an activator of signal transducer and activator of transcription(STAT)3 and the nuclear factor kappa B pathway.Another proposed epigenetic mechanism by which HCC may form is the aberrant silencing of tumor suppressor genes by DNA Methyltransferases.HDV antigens have also been associated with increased histone H3 acetylation of the clusterin promoter.This enhances the expression of clusterin in infected cells,increasing cell survival potential.Any contribution of HBV DNA integration with chromosomes of infected hepatocytes is not clear at this stage.The targeted inhibition of STAT3 and cyclophilin,and augmentation of peroxisome proliferatoractivated receptor γ have a potential therapeutic role in HCC. | Zaigham Abbas Minaam Abbas Sarim Abbas Lubna Shazi | 2015 | World Journal of Hepatology2015，7，5： | 5 |
| 2 | Agent selection and protective effects during single droplet drying of bacteria显示文摘 | Sarim K Meng W W Darryl M | 2015 | Food Chem2015，166，： | 1 |
| 3 | Chemistry of uranium, thorium, and radium isotopes in the Ganga-Brahmaputra river system: Weathering processes and fluxes to the Bay of the Bengal显示文摘 | SARIM M M KRISHNASWAMI K SOMAYAJULU B L K | 1990 | Geochim Cosmochim Aeta1990，54，： | 1 |
| 4 | A female advantage in the recognition of emotional facial expressions:test of an evolutionary hypothesis 显示文摘 | HAMPSON E SARIM ANDERS V | 2006 | Evolution and Human Behavior2006，27，6： | 1 |
| 5 | Fine-scale spatial variability of physical and biological soil properties in Kingston,Rhode Island显示文摘 | Jose A Amador Yong Wang Mary C Sarim Josef H Gorres | 2000 | Geoderma2000，98，： | 1 |
| 6 | 建筑结构抗下击暴流研究综述显示文摘介绍国内外对建筑结构抗下击暴流研究的主要科研成果,从现场实测、解析模型、数值模拟、风洞试验和结构的风振响应分析5个方面展开论述,关注与人民生产生活息息相关的各类建筑结构,系统总结现阶段国内外对结构抗下击暴流的研究进展和存在的问题。对建筑结构抗下击暴流的研究方向进行了展望。 | 田利 毕文哲 SIDDIQUI Sarim Saleem 刘凯悦 | 2021 | 山东大学学报(工学版)2021，51，5： | 1 |
| 7 | Oxidation behavior of WC-Co显示文摘 | BASU S N SARIM V K | 1996 | Materials Science and Engineering A1996，209，12： | 1 |
| 8 | Chronic nonspecific lung disease and alcohol consumption显示文摘 | SariM Luci-Palai S Horton RJ | 1977 | Environ Res1977，14，1： | 1 |
| 9 | Fine-scale spatial variability of physical and biological soil properties in Kingston,Rhode Island显示文摘 | Jose A Amador Yong Wang Mary C Sarim JosefH Gorres | 2000 | Geoderma2000，98，： | 1 |
| 10 | A new approach for measuring the validity of the fuzzy c - means algorithm 显示文摘 | George E Tsekouras Haralambos Sarim veis | 2004 | Advances in Engineering Software2004，，35： | 1 |
| 11 | Estimating the prevalence of anaemia:a comparison of three methods显示文摘 | SARIM DE PEE S MARTINI E | 2001 | Bull WHO2001，79，： | 1 |
| 12 | Effect of particle size distribution on magnetic behavior of nanoparticles with uniaxial anisotropy显示文摘The effect of particle size distribution on the field and temperature dependence of the hysteresis loop features like coercivity(H_C), remanence(M_R), and blocking temperature(T_B) is simulated for an ensemble of single domain ferromagnetic nanoparticles with uniaxial anisotropy. Our simulations are based on the two-state model for T < T_B and the metropolis Monte-Carlo method for T > T_B. It is found that the increase in the grain size significantly enhances H_C and T_B. The presence of interparticle exchange interaction in the system suppresses H_C but causes MRto significantly increase.Our results show that the parameters associated with the particle size distribution(D_(d,δ)) such as the mean particle size d and standard-deviation δ play key roles in the magnetic behavior of the system. | S Rizwan Ali Farah Naz Humaira Akber M Naeem S Imran Ali S Abdul Basit M Sarim Sadaf Qaseem | 2018 | Chinese Physics B2018，27，9： | 0 |
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