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| 1 | Long-term outcomes of interventions for radiation-induced xerostomia:A review显示文摘Xerostomia, or dry mouth, is a significant problem affecting quality of life in patients treated with radiation therapy for head and neck cancer. Strategies for reduction of xerostomia burden vary widely, with options including: sialagogue medications, saliva substitutes, acupuncture, vitamins, hyperbaric oxygen,submandibular gland transfer, and acupuncture or associated treatments. In this review, we sought to evaluate long-term outcomes of patients treated with various interventions for radiation-induced xerostomia. A literature search was performed using the terms 'xerostomia' and 'radiation' or 'radiotherapy'; all prospective clinical trials were evaluated, and only studies that reported 1 year follow up were included. The search results yielded 2193 studies, 1977 of which were in English. Of those, 304 were clinical trials or clinical studies. After abstract review, 23 trials were included in the review evaluating the following treatment modalities: pilocarpine(three); cevimeline(one); amifostine(eleven);submandibular gland transfer(five); acupuncture like transcutaneous electrical nerve stimulation(ALTENS)(one); hyperbaric oxygen(one); and acupuncture(one). Pilocarpine, cevimeline, and amifostine have been shown in some studies to improve xerostomia outcomes, at the cost of toxicity. ALTENS has similar efficacy with fewer side effects. Submandibular gland transfer is effective but requires an elective surgery, and thus may not always be appropriate or practical.The use of intensity-modulated radiation therapy, in addition to dose deescalation in select patients, may result in fewer patients with late xerostomia,reducing the need for additional interventions. | Sung Jun Ma Charlotte I Rivers Lucas M Serra Anurag K Singh | 2019 | World Journal of Clinical Oncology2019，10，1： | 4 |
| 2 | Orthopaedic care provided by the 14th combat support hospital in support of humanitarian and disaster relief after hurricane Maria in Puerto Rico显示文摘On September 20,2017 Hurricane Maria,a category 4 hurricane,made landfall on the eastern coast of Puerto Rico.This was preceded by Hurricane Irma,a category 5 hurricane,which passed just off the coast 13 d prior.The destruction from both Hurricane Irma and Maria precipitated a coordinated federal response which included the Federal Emergency Management Agency(FEMA)and the United States military.The United States Army dispatched the 14^th Combat Support Hospital(CSH)to Humacao,a city on the eastern side of the island where Maria made landfall.The mission of the 14^th CSH was to provide medical humanitarian aid and conduct disaster relief operations in support of the government of Puerto Rico and FEMA.During the 14^th CSH deployment to Puerto Rico,1157 patients were evaluated and treated.Fifty-seven operative cases were performed to include 23 orthopaedic cases.The mean age of the orthopaedic patients treated was 45.7 years(range 13-76 years).The most common operation was irrigation and debridement of open contaminated and/or infected wounds.Patients presented a mean 10.8 d from their initial injury(range 1-40 d).Fractures and infections were the most common diagnoses with the greatest delay in treatment from the initial date of injury.The deployment of the 14^th CSH to Puerto Rico was unique in its use of air transport,language and local customs encountered,as well as deployment to a location outside the continental United States.These factors coupled with the need for rapid deployment of the 14^th CSH provided valuable experience which will undoubtedly enable future success in similar endeavors. | Nathan Lanham Kyle Bockelman Fernando Lopez Marc M Serra Bradford Scanlan | 2020 | World Journal of Orthopedics2020，11，2： | 2 |
| 3 | Predictors of morbidity and mortality after the first episode of upper gastrointestinal bleeding in liver cirrhosis显示文摘 | Juan A.del Olmo Andrés Pe?a Miguel A Serra Abdallah H Wassel Adolfo Benages José M Rodrigo | 2000 | Journal of Hepatology2000，，1： | 2 |
| 4 | Contrast-enhanced ultras- ound for blunt abdominal trauma显示文摘 | Valentino M Serra C Pavlica P | 2007 | Semin Ultrasound CT MR2007，28，2： | 1 |
| 5 | Coloring of titanium through laser oxidation: Comparative study with anodizing 显示文摘 | Perez Del P Ferndndez-Pradas J M Serra P | 2004 | Surface and Coatings Technology2004，187，1： | 1 |
| 6 | Glucocorticoid receptor deficiency increases vulnerability of the nigrostriatal dopaminergic system: critical role of glial nitric oxide显示文摘 | MORALE M C SERRA P A DELOGU M R | 2004 | FASEB J2004，18，1： | 1 |
| 7 | Lung MRI as a possible alternative to CT scan for patients with primary immune deficiencies and increased radiosensitivity显示文摘 | Serra G Milito C Mitrevski M | 2011 | Chest2011，140，： | 1 |
| 8 | A global movement toward an ecosystem approach to management of marine resources显示文摘 | Sherman K Sissenwine M Christensen V Duda A Hempel G Ibe C Levin S Liuch-Belda D Matishov G McGlade J O'Toole M Switzinger S Serra R Skjoldat H-R Tang Q Thulin J Vandeweerd V Zwanenburg K | | 0，，： | 1 |
| 9 | Ap- plicability of muhisyringe chromatography coupled to cold- vapor atomic fluorescence spectrometry for mercury speci- ation analysis 显示文摘 | Guzman-Mar J L Hinojosa-Reyes L Serra A M | 2011 | Analytica Chimica Acta2011，708，12： | 1 |
| 10 | Os- RMC, a negative regulator of salt stress response in rice, is regu- lated by two AP2/ERF transcription factors显示文摘 | SERRA T S FIGUEIREDO D D CORDEIRO A M | 2013 | Plant Molecular Biology2013，82，45： | 1 |
| 11 | Molecular characterization of CEVd strains that induce different phenotypes in Gynura aurantiaca- structure-patho- genicity relationships 显示文摘 | Chaffai M Serra P Gandia M | 2007 | Archives of Virology2007，152，： | 1 |
| 12 | Analysis of pressure buildup data from a well in a multiwell system显示文摘 | Onur M Serra KV Reynolds AC | 1991 | SPE Formation Evalua- tion1991，6，1： | 1 |
| 13 | Predictive factors and tong-term chnicfl conse- quences of persistent leti bundle branch block following trmmcatheter aortic valve implantation with a balloo-expandable valve显示文摘 | Urena M Mok M Serra V et at | 2012 | J Am con Cardiol2012，60，18： | 1 |
| 14 | Adaptation of the Hall-Findlay technique for simultaneous contralateral reduction in delayed breast reconstruction with extended latissimus dorsi flap 显示文摘 | SERRA M P SINHA M | 2009 | J Plast Reconstr Aesthet Surg2009，21，： | 1 |
| 15 | Resistance to pepper mild mottle tobamovirus conferred by the 54-kDa gene sequence in transgenic plants does not require expression of the wild-type 54-kDa protein显示文摘 | GARCIA-LUQUE I SERRA M T | 1996 | Virology1996，219，： | 1 |
| 16 | Paraquat intoxication 显示文摘 | SERRA A DOMINGOS F PRATA M M | 2003 | Acta Med Port2003，16，1： | 1 |
| 17 | Blunt abdominal trauma: emergency contrast-enhanced sonography for detection of solid or- gan injuries显示文摘 | Valentino M Serra C Zironi G | 2006 | Am J Roentgenol2006，186，5： | 1 |
| 18 | Optimum Design of Thin-Walled Closed Cross Sections: A Numerical Approach显示文摘 | M Serra | 2005 | Computers & Structures2005，83，4： | 1 |
| 19 | Assessment of the aroma profiles of low–alcohol beers using HS–SPME–GC–MS显示文摘 | Riu–Aumatell M MiróP Serra–Cayuela A | 2014 | Food Research International2014，57，19： | 1 |
| 20 | Degrada- tion of phenol by Rhodococcus erythropolis UPV-1 immobilized on Biolite in a packed-bed reactor 显示文摘 | Prieto M B Hidalgo A Serra J L | 2002 | J Biotechnol2002，97，1： | 1 |
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